Aliases for CCDC9B Gene

Aliases for CCDC9B Gene

  • Coiled-Coil Domain Containing 9B 2 3 5
  • Coiled-Coil Domain-Containing Protein 9B 3 4
  • C15orf52 3 4
  • Chromosome 15 Open Reading Frame 52 2
  • Uncharacterized Protein C15orf52 3
  • FLJ43339 2
  • CCDC9B 5

External Ids for CCDC9B Gene

Previous HGNC Symbols for CCDC9B Gene

  • C15orf52

Previous GeneCards Identifiers for CCDC9B Gene

  • GC15M040333
  • GC15M040344

Summaries for CCDC9B Gene

GeneCards Summary for CCDC9B Gene

CCDC9B (Coiled-Coil Domain Containing 9B) is a Protein Coding gene. An important paralog of this gene is CCDC9.

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for CCDC9B Gene

Genomics for CCDC9B Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for CCDC9B Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around CCDC9B on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for CCDC9B

Genomic Locations for CCDC9B Gene

Latest Assembly
chr15:40,331,452-40,340,967
(GRCh38/hg38)
Size:
9,516 bases
Orientation:
Minus strand

Previous Assembly
chr15:40,623,653-40,633,168
(GRCh37/hg19 by Entrez Gene)
Size:
9,516 bases
Orientation:
Minus strand

chr15:40,623,653-40,633,168
(GRCh37/hg19 by Ensembl)
Size:
9,516 bases
Orientation:
Minus strand

Genomic View for CCDC9B Gene

Genes around CCDC9B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CCDC9B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CCDC9B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CCDC9B Gene

Proteins for CCDC9B Gene

  • Protein details for CCDC9B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6ZUT6-CCD9B_HUMAN
    Recommended name:
    Coiled-coil domain-containing protein 9B
    Protein Accession:
    Q6ZUT6
    Secondary Accessions:
    • B9EIQ8
    • Q68DG9
    • Q6ZTM3
    • Q6ZU22

    Protein attributes for CCDC9B Gene

    Size:
    534 amino acids
    Molecular mass:
    57325 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=CAH18251.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for CCDC9B Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for CCDC9B Gene

Post-translational modifications for CCDC9B Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CCDC9B Gene

No data available for DME Specific Peptides for CCDC9B Gene

Domains & Families for CCDC9B Gene

Gene Families for CCDC9B Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for CCDC9B Gene

InterPro:
genes like me logo Genes that share domains with CCDC9B: view

No data available for Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for CCDC9B Gene

Function for CCDC9B Gene

Phenotypes From GWAS Catalog for CCDC9B Gene

Gene Ontology (GO) - Molecular Function for CCDC9B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003723 RNA binding HDA 22658674
genes like me logo Genes that share ontologies with CCDC9B: view
genes like me logo Genes that share phenotypes with CCDC9B: view

miRNA for CCDC9B Gene

miRTarBase miRNAs that target CCDC9B

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for CCDC9B Gene

Localization for CCDC9B Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for CCDC9B gene
Compartment Confidence
nucleus 3
cytosol 2
extracellular 1
golgi apparatus 1
lysosome 0

Subcellular locations from the

Human Protein Atlas (HPA)
  • Cytosol (2)
  • Nucleoplasm (2)
See all subcellular structures

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for CCDC9B Gene

Pathways & Interactions for CCDC9B Gene

PathCards logo

SuperPathways for CCDC9B Gene

No Data Available

Interacting Proteins for CCDC9B Gene

Gene Ontology (GO) - Biological Process for CCDC9B Gene

None

No data available for Pathways by source and SIGNOR curated interactions for CCDC9B Gene

Drugs & Compounds for CCDC9B Gene

No Compound Related Data Available

Transcripts for CCDC9B Gene

mRNA/cDNA for CCDC9B Gene

1 REFSEQ mRNAs :
13 NCBI additional mRNA sequence :
7 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for CCDC9B Gene

No ASD Table

Relevant External Links for CCDC9B Gene

GeneLoc Exon Structure for
CCDC9B

Expression for CCDC9B Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for CCDC9B

Evidence on tissue expression from TISSUES for CCDC9B Gene

  • Liver(4)
No Expression Related Data Available

Primer products for research

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for CCDC9B Gene

Orthologs for CCDC9B Gene

This gene was present in the common ancestor of chordates.

Orthologs for CCDC9B Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia C15H15orf52 29
  • 97.88 (n)
C15orf52 30
  • 97 (a)
OneToOne
Dog
(Canis familiaris)
Mammalia C30H15orf52 29
  • 81.45 (n)
C15orf52 30
  • 71 (a)
OneToOne
Cow
(Bos Taurus)
Mammalia C10H15orf52 29
  • 81.18 (n)
C15orf52 30
  • 68 (a)
OneToOne
Mouse
(Mus musculus)
Mammalia A430105I19Rik 29 30
  • 74.72 (n)
OneToOne
Ccdc9b 16
Platypus
(Ornithorhynchus anatinus)
Mammalia C15orf52 30
  • 47 (a)
OneToOne
Oppossum
(Monodelphis domestica)
Mammalia C15orf52 30
  • 37 (a)
OneToOne
Chicken
(Gallus gallus)
Aves C5H15ORF52 29
  • 58.25 (n)
Lizard
(Anolis carolinensis)
Reptilia C15orf52 30
  • 29 (a)
OneToOne
Zebrafish
(Danio rerio)
Actinopterygii C17H15orf52 30
  • 22 (a)
OneToOne
Species where no ortholog for CCDC9B was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rat (Rattus norvegicus)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Tropical Clawed Frog (Silurana tropicalis)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)

Evolution for CCDC9B Gene

ENSEMBL:
Gene Tree for CCDC9B (if available)
TreeFam:
Gene Tree for CCDC9B (if available)
Alliance of Genome Resources:
Additional Orthologs for CCDC9B

Paralogs for CCDC9B Gene

Paralogs for CCDC9B Gene

genes like me logo Genes that share paralogs with CCDC9B: view

Variants for CCDC9B Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for CCDC9B Gene

SNP ID Clinical significance and condition Chr 15 pos Variation AA Info Type
VAR_035620 A colorectal cancer sample p.Gly189Glu

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for CCDC9B Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for CCDC9B Gene

Variant ID Type Subtype PubMed ID
esv34145 CNV loss 18971310
nsv1160287 CNV duplication 26073780
nsv510660 CNV deletion 20534489
nsv827305 CNV gain 20364138

Variation tolerance for CCDC9B Gene

Residual Variation Intolerance Score: 94.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.68; 65.95% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for CCDC9B Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
CCDC9B
Leiden Open Variation Database (LOVD)
CCDC9B

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CCDC9B Gene

Disorders for CCDC9B Gene

Additional Disease Information for CCDC9B

No disorders were found for CCDC9B Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CCDC9B Gene

Publications for CCDC9B Gene

  1. Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers. (PMID: 27684187) Rosenbluh J … Hahn WC (Cell systems 2016) 3
  2. ATPase-Modulated Stress Granules Contain a Diverse Proteome and Substructure. (PMID: 26777405) Jain S … Parker R (Cell 2016) 3
  3. A human interactome in three quantitative dimensions organized by stoichiometries and abundances. (PMID: 26496610) Hein MY … Mann M (Cell 2015) 3
  4. The central role of EED in the orchestration of polycomb group complexes. (PMID: 24457600) Cao Q … Chinnaiyan AM (Nature communications 2014) 3
  5. An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. (PMID: 24275569) Bian Y … Zou H (Journal of proteomics 2014) 4

Products for CCDC9B Gene

Sources for CCDC9B Gene