Aliases for CCDC97 Gene

Aliases for CCDC97 Gene

  • Coiled-Coil Domain Containing 97 2 3 5
  • Coiled-Coil Domain-Containing Protein 97 3 4

External Ids for CCDC97 Gene

Previous GeneCards Identifiers for CCDC97 Gene

  • GC19P046508
  • GC19P041816
  • GC19P038249

Summaries for CCDC97 Gene

GeneCards Summary for CCDC97 Gene

CCDC97 (Coiled-Coil Domain Containing 97) is a Protein Coding gene. Diseases associated with CCDC97 include Megacystis-Microcolon-Intestinal Hypoperistalsis Syndrome.

Additional gene information for CCDC97 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for CCDC97 Gene

Genomics for CCDC97 Gene

GeneHancer (GH) Regulatory Elements for CCDC97 Gene

Promoters and enhancers for CCDC97 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around CCDC97 on UCSC Golden Path with GeneCards custom track

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for CCDC97

Top Transcription factor binding sites by QIAGEN in the CCDC97 gene promoter:
  • c-Myc
  • E2F
  • E2F-1
  • E2F-2
  • E2F-3a
  • E2F-4
  • E2F-5
  • FOXO4
  • Max
  • ZIC2

Genomic Locations for CCDC97 Gene

Genomic Locations for CCDC97 Gene
chr19:41,310,172-41,324,883
(GRCh38/hg38)
Size:
14,712 bases
Orientation:
Plus strand
chr19:41,816,094-41,830,788
(GRCh37/hg19)
Size:
14,695 bases
Orientation:
Plus strand

Genomic View for CCDC97 Gene

Genes around CCDC97 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CCDC97 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CCDC97 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CCDC97 Gene

Proteins for CCDC97 Gene

  • Protein details for CCDC97 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96F63-CCD97_HUMAN
    Recommended name:
    Coiled-coil domain-containing protein 97
    Protein Accession:
    Q96F63
    Secondary Accessions:
    • Q658N6
    • Q96IF3

    Protein attributes for CCDC97 Gene

    Size:
    343 amino acids
    Molecular mass:
    38947 Da
    Quaternary structure:
    No Data Available

neXtProt entry for CCDC97 Gene

Post-translational modifications for CCDC97 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CCDC97 Gene

No data available for DME Specific Peptides for CCDC97 Gene

Domains & Families for CCDC97 Gene

Gene Families for CCDC97 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for CCDC97 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for CCDC97 Gene

GenScript: Design optimal peptide antigens:
  • Coiled-coil domain-containing protein 97 (CCD97_HUMAN)
genes like me logo Genes that share domains with CCDC97: view

No data available for Graphical View of Domain Structure and UniProtKB/Swiss-Prot for CCDC97 Gene

Function for CCDC97 Gene

Phenotypes From GWAS Catalog for CCDC97 Gene

genes like me logo Genes that share phenotypes with CCDC97: view

Animal Model Products

CRISPR Products

miRNA for CCDC97 Gene

miRTarBase miRNAs that target CCDC97

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for CCDC97 Gene

Localization for CCDC97 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for CCDC97 gene
Compartment Confidence
nucleus 3
cytosol 3
plasma membrane 2

Subcellular locations from the

Human Protein Atlas (HPA)
  • Nucleoplasm (3)
  • Cytosol (2)
  • Plasma membrane (2)
See all subcellular structures

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for CCDC97 Gene

Pathways & Interactions for CCDC97 Gene

PathCards logo

SuperPathways for CCDC97 Gene

No Data Available

Gene Ontology (GO) - Biological Process for CCDC97 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for CCDC97 Gene

Drugs & Compounds for CCDC97 Gene

No Compound Related Data Available

Transcripts for CCDC97 Gene

mRNA/cDNA for CCDC97 Gene

2 REFSEQ mRNAs :
6 NCBI additional mRNA sequence :
3 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for CCDC97 Gene

No ASD Table

Relevant External Links for CCDC97 Gene

GeneLoc Exon Structure for
CCDC97

Expression for CCDC97 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for CCDC97 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for CCDC97 Gene

This gene is overexpressed in Blymphocyte (19.5) and Testis (11.2).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for CCDC97 Gene



Protein tissue co-expression partners for CCDC97 Gene

- Elite partner

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for CCDC97

SOURCE GeneReport for Unigene cluster for CCDC97 Gene:

Hs.437497

Evidence on tissue expression from TISSUES for CCDC97 Gene

  • Stomach(4.2)
genes like me logo Genes that share expression patterns with CCDC97: view

No data available for mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for CCDC97 Gene

Orthologs for CCDC97 Gene

This gene was present in the common ancestor of animals.

Orthologs for CCDC97 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia CCDC97 31
  • 89 (a)
OneToOne
dog
(Canis familiaris)
Mammalia CCDC97 31 30
  • 87.29 (n)
OneToOne
cow
(Bos Taurus)
Mammalia CCDC97 31 30
  • 85.92 (n)
OneToOne
rat
(Rattus norvegicus)
Mammalia Ccdc97 30
  • 79.94 (n)
mouse
(Mus musculus)
Mammalia Ccdc97 17 31 30
  • 79.74 (n)
platypus
(Ornithorhynchus anatinus)
Mammalia CCDC97 31
  • 64 (a)
OneToOne
chicken
(Gallus gallus)
Aves LOC101748852 30
  • 57.58 (n)
lizard
(Anolis carolinensis)
Reptilia CCDC97 31
  • 56 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia ccdc97 30
  • 60.08 (n)
zebrafish
(Danio rerio)
Actinopterygii LOC793800 30
  • 54.58 (n)
CCDC97 31
  • 40 (a)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta CG7810 31
  • 26 (a)
OneToOne
worm
(Caenorhabditis elegans)
Secernentea R10D12.13 31
  • 27 (a)
OneToOne
Species where no ortholog for CCDC97 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for CCDC97 Gene

ENSEMBL:
Gene Tree for CCDC97 (if available)
TreeFam:
Gene Tree for CCDC97 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for CCDC97: view image

Paralogs for CCDC97 Gene

No data available for Paralogs for CCDC97 Gene

Variants for CCDC97 Gene

Additional dbSNP identifiers (rs#s) for CCDC97 Gene

Variation tolerance for CCDC97 Gene

Residual Variation Intolerance Score: 55.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.15; 23.31% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for CCDC97 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
CCDC97

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Structural Variations from Database of Genomic Variants (DGV) for CCDC97 Gene

Disorders for CCDC97 Gene

MalaCards: The human disease database

(1) MalaCards diseases for CCDC97 Gene - From: DISEASES

Disorder Aliases PubMed IDs
megacystis-microcolon-intestinal hypoperistalsis syndrome
  • visceral myopathy
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for CCDC97

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
genes like me logo Genes that share disorders with CCDC97: view

No data available for UniProtKB/Swiss-Prot and Genatlas for CCDC97 Gene

Publications for CCDC97 Gene

  1. Genetic susceptibility to distinct bladder cancer subphenotypes. (PMID: 19692168) Guey LT … EPICURO/Spanish Bladder Cancer Study investigators (European urology 2010) 3 41 54
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 2 3 54
  3. Nuclear actin interactome analysis links actin to KAT14 histone acetyl transferase and mRNA splicing. (PMID: 30890647) Viita T … Vartiainen MK (Journal of cell science 2019) 3 54
  4. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 54
  5. WDR76 Co-Localizes with Heterochromatin Related Proteins and Rapidly Responds to DNA Damage. (PMID: 27248496) Gilmore JM … Washburn MP (PloS one 2016) 3 54

Products for CCDC97 Gene

Sources for CCDC97 Gene