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Aliases for CCDC97 Gene

Aliases for CCDC97 Gene

  • Coiled-Coil Domain Containing 97 2 3 5
  • Coiled-Coil Domain-Containing Protein 97 3

External Ids for CCDC97 Gene

Previous GeneCards Identifiers for CCDC97 Gene

  • GC19P046508
  • GC19P041816
  • GC19P038249

Summaries for CCDC97 Gene

GeneCards Summary for CCDC97 Gene

CCDC97 (Coiled-Coil Domain Containing 97) is a Protein Coding gene.

Additional gene information for CCDC97 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCDC97 Gene

Genomics for CCDC97 Gene

GeneHancer (GH) Regulatory Elements for CCDC97 Gene

Promoters and enhancers for CCDC97 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH19J041294 Promoter/Enhancer 2.9 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 745.9 -6.9 -6892 16.8 CLOCK MLX ZFP64 FEZF1 DMAP1 YBX1 IRF4 YY1 ZNF213 E2F8 CCDC97 ZNF526 HNRNPUL1 SNRPA ZNF574 ENSG00000269843 COQ8B TGFB1 AXL ITPKC
GH19J040713 Promoter/Enhancer 2.9 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 86.1 -591.8 -591841 9.2 CLOCK FEZF1 DMAP1 IRF4 YY1 ZNF213 E2F8 ZNF416 ZNF143 ZNF548 ITPKC NUMBL COQ8B SNRPA HNRNPUL1 ENSG00000269843 CCDC97 ZNF780B FBL AKT2
GH19J041882 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 87.2 +576.5 576470 9.2 MLX FEZF1 DMAP1 YBX1 IRF4 YY1 ZNF213 E2F8 ZNF143 ZNF548 ARHGEF1 ZNF526 CCDC97 HNRNPUL1 ZNF574 RPS19 RABAC1 ENSG00000271299 CEACAMP1 CYP2G2P
GH19J040747 Promoter/Enhancer 2.6 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 66.7 -557.4 -557428 9.8 CLOCK MLX ZFP64 FEZF1 DMAP1 YBX1 YY1 ZNF213 E2F8 ZNF416 SNRPA C19orf54 HNRNPUL1 ENSG00000269843 CCDC97 COQ8B ZNF780A AKT2 FBL ZNF780B
GH19J040596 Promoter/Enhancer 2.6 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 64.6 -708.5 -708493 10 CLOCK MLX FEZF1 DMAP1 YY1 ZNF213 E2F8 ZNF416 ZNF143 ZNF548 LTBP4 HNRNPUL1 SNRPA ENSG00000269843 ZNF780B CCDC97 ZNF780A AKT2 FBL COQ8B
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around CCDC97 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the CCDC97 gene promoter:

Genomic Locations for CCDC97 Gene

Genomic Locations for CCDC97 Gene
chr19:41,310,189-41,324,883
(GRCh38/hg38)
Size:
14,695 bases
Orientation:
Plus strand
chr19:41,816,094-41,830,788
(GRCh37/hg19)

Genomic View for CCDC97 Gene

Genes around CCDC97 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CCDC97 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CCDC97 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CCDC97 Gene

Proteins for CCDC97 Gene

  • Protein details for CCDC97 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96F63-CCD97_HUMAN
    Recommended name:
    Coiled-coil domain-containing protein 97
    Protein Accession:
    Q96F63
    Secondary Accessions:
    • Q658N6
    • Q96IF3

    Protein attributes for CCDC97 Gene

    Size:
    343 amino acids
    Molecular mass:
    38947 Da
    Quaternary structure:
    No Data Available

neXtProt entry for CCDC97 Gene

Post-translational modifications for CCDC97 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CCDC97 Gene

No data available for DME Specific Peptides for CCDC97 Gene

Domains & Families for CCDC97 Gene

Gene Families for CCDC97 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for CCDC97 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for CCDC97 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CCDC97: view

No data available for UniProtKB/Swiss-Prot for CCDC97 Gene

Function for CCDC97 Gene

Phenotypes From GWAS Catalog for CCDC97 Gene

genes like me logo Genes that share phenotypes with CCDC97: view

Animal Model Products

miRNA for CCDC97 Gene

miRTarBase miRNAs that target CCDC97

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for CCDC97 Gene

Localization for CCDC97 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for CCDC97 gene
Compartment Confidence
nucleus 5
cytosol 3
plasma membrane 2

Subcellular locations from the

Human Protein Atlas (HPA)
  • Nucleoplasm (3)
  • Cytosol (2)
  • Plasma membrane (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for CCDC97 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005686 U2 snRNP IBA --
genes like me logo Genes that share ontologies with CCDC97: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for CCDC97 Gene

Pathways & Interactions for CCDC97 Gene

SuperPathways for CCDC97 Gene

No Data Available

Gene Ontology (GO) - Biological Process for CCDC97 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for CCDC97 Gene

Drugs & Compounds for CCDC97 Gene

No Compound Related Data Available

Transcripts for CCDC97 Gene

mRNA/cDNA for CCDC97 Gene

Unigene Clusters for CCDC97 Gene

Coiled-coil domain containing 97:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for CCDC97 Gene

No ASD Table

Relevant External Links for CCDC97 Gene

GeneLoc Exon Structure for
CCDC97
ECgene alternative splicing isoforms for
CCDC97

Expression for CCDC97 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for CCDC97 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for CCDC97 Gene

This gene is overexpressed in Blymphocyte (19.5) and Testis (11.2).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for CCDC97 Gene



Protein tissue co-expression partners for CCDC97 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of CCDC97 Gene:

CCDC97

SOURCE GeneReport for Unigene cluster for CCDC97 Gene:

Hs.437497

Evidence on tissue expression from TISSUES for CCDC97 Gene

  • Stomach(4.2)
genes like me logo Genes that share expression patterns with CCDC97: view

No data available for mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for CCDC97 Gene

Orthologs for CCDC97 Gene

This gene was present in the common ancestor of animals.

Orthologs for CCDC97 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia CCDC97 34
  • 89 (a)
OneToOne
dog
(Canis familiaris)
Mammalia CCDC97 34 33
  • 87.29 (n)
OneToOne
cow
(Bos Taurus)
Mammalia CCDC97 34 33
  • 85.92 (n)
OneToOne
rat
(Rattus norvegicus)
Mammalia Ccdc97 33
  • 79.94 (n)
mouse
(Mus musculus)
Mammalia Ccdc97 16 34 33
  • 79.74 (n)
platypus
(Ornithorhynchus anatinus)
Mammalia CCDC97 34
  • 64 (a)
OneToOne
chicken
(Gallus gallus)
Aves LOC101748852 33
  • 57.58 (n)
lizard
(Anolis carolinensis)
Reptilia CCDC97 34
  • 56 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia ccdc97 33
  • 60.08 (n)
zebrafish
(Danio rerio)
Actinopterygii LOC793800 33
  • 54.58 (n)
CCDC97 34
  • 40 (a)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta CG7810 34
  • 26 (a)
OneToOne
worm
(Caenorhabditis elegans)
Secernentea R10D12.13 34
  • 27 (a)
OneToOne
Species where no ortholog for CCDC97 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for CCDC97 Gene

ENSEMBL:
Gene Tree for CCDC97 (if available)
TreeFam:
Gene Tree for CCDC97 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for CCDC97: view image

Paralogs for CCDC97 Gene

No data available for Paralogs for CCDC97 Gene

Variants for CCDC97 Gene

Sequence variations from dbSNP and Humsavar for CCDC97 Gene

SNP ID Clin Chr 19 pos Variation AA Info Type
rs1000226840 -- 41,323,608(+) A/C 3_prime_UTR_variant, genic_downstream_transcript_variant
rs1000263906 -- 41,320,887(+) C/G/T 3_prime_UTR_variant, intron_variant
rs1000317775 -- 41,309,546(+) G/A upstream_transcript_variant
rs1000491727 -- 41,315,920(+) C/A/T intron_variant
rs1000558823 -- 41,317,272(+) A/G intron_variant

Variation tolerance for CCDC97 Gene

Residual Variation Intolerance Score: 55.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.15; 23.31% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for CCDC97 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
CCDC97

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for CCDC97 Gene

Disorders for CCDC97 Gene

Additional Disease Information for CCDC97

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology

No disorders were found for CCDC97 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CCDC97 Gene

Publications for CCDC97 Gene

  1. Genetic susceptibility to distinct bladder cancer subphenotypes. (PMID: 19692168) Guey LT … EPICURO/Spanish Bladder Cancer Study investigators (European urology 2010) 3 44 58
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 2 3 58
  3. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 58
  4. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin EL … Gygi SP (Cell 2015) 3 58
  5. Panorama of ancient metazoan macromolecular complexes. (PMID: 26344197) Wan C … Emili A (Nature 2015) 3 58

Products for CCDC97 Gene

Sources for CCDC97 Gene

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