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Hepatitis delta virus (HDV) is a pathogenic human virus whose RNA genome and replication cycle resemble those of plant viroids. Delta-interacting protein A (DIPA), a cellular gene product, has been found to have homology to hepatitis delta virus antigen (HDAg). DIPA interacts with the viral antigen, HDAg, and can affect HDV replication in vitro. [provided by RefSeq, Jul 2008]
CCDC85B (Coiled-Coil Domain Containing 85B) is a Protein Coding gene. Diseases associated with CCDC85B include Hepatitis and Separation Anxiety Disorder. An important paralog of this gene is CCDC85C.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005515 | protein binding | IPI | 16189514 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005634 | nucleus | IEA,IDA | 17014843 |
GO:0005737 | cytoplasm | IEA | -- |
GO:0005813 | centrosome | IDA | 17014843 |
GO:0005815 | microtubule organizing center | IEA | -- |
GO:0005856 | cytoskeleton | IEA | -- |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0016032 | viral process | IEA | -- |
GO:0030154 | cell differentiation | IEA | -- |
GO:0030308 | negative regulation of cell growth | IDA | 17873903 |
GO:0040008 | regulation of growth | IEA | -- |
GO:0045599 | negative regulation of fat cell differentiation | IEA,ISS | -- |
This gene was present in the common ancestor of animals.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | CCDC85B 30 31 |
|
OneToOne | |
Cow (Bos Taurus) |
Mammalia | CCDC85B 31 |
|
OneToOne | |
Dog (Canis familiaris) |
Mammalia | CCDC85B 30 31 |
|
OneToOne | |
Rat (Rattus norvegicus) |
Mammalia | Ccdc85b 30 |
|
||
Mouse (Mus musculus) |
Mammalia | Ccdc85b 30 17 31 |
|
OneToOne | |
Oppossum (Monodelphis domestica) |
Mammalia | CCDC85B 31 |
|
OneToOne | |
Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | ccdc85b 30 |
|
||
Zebrafish (Danio rerio) |
Actinopterygii | ccdc85b 30 31 |
|
OneToOne | |
Fruit Fly (Drosophila melanogaster) |
Insecta | CG17265 31 |
|
OneToMany | |
Worm (Caenorhabditis elegans) |
Secernentea | F29G9.2 31 |
|
OneToMany | |
Sea Squirt (Ciona savignyi) |
Ascidiacea | CSA.4851 31 |
|
OneToMany |
Variant ID | Type | Subtype | PubMed ID |
---|---|---|---|
esv2759834 | CNV | gain | 17122850 |
nsv1159905 | CNV | duplication | 26073780 |
nsv555215 | CNV | loss | 21841781 |
nsv832191 | CNV | loss | 17160897 |
nsv951019 | CNV | deletion | 24416366 |
Disorder | Aliases | PubMed IDs |
---|---|---|
hepatitis |
|
|
separation anxiety disorder |
|
|
relapsing fever |
|
|
hydrocephalus |
|
|