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Aliases for CCDC82 Gene

Aliases for CCDC82 Gene

  • Coiled-Coil Domain Containing 82 2 3 5
  • Coiled-Coil Domain-Containing Protein 82 3
  • HSPC048 3

External Ids for CCDC82 Gene

Previous GeneCards Identifiers for CCDC82 Gene

  • GC11M095726
  • GC11M096085
  • GC11M092152

Summaries for CCDC82 Gene

GeneCards Summary for CCDC82 Gene

CCDC82 (Coiled-Coil Domain Containing 82) is a Protein Coding gene.

Additional gene information for CCDC82 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCDC82 Gene

Genomics for CCDC82 Gene

GeneHancer (GH) Regulatory Elements for CCDC82 Gene

Promoters and enhancers for CCDC82 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH11J096388 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 733.4 +0.1 105 2.5 HDGF PKNOX1 SMAD1 MLX ARID4B SIN3A DMAP1 ZNF2 YY1 POLR2B CCDC82 JRKL FAM76B MAML2
GH11J096506 Promoter 1 EPDnew 650.1 -117.0 -116983 0.1 SMARCE1 TAF9B MTA2 ZNF740 RNF2 GTF2E2 NCOA1 MNT ZEB2 ZNF395 ENSG00000256684 LOC105369443 JRKL-AS1 CCDC82 JRKL
GH11J096391 Enhancer 0.3 Ensembl 650.7 -1.7 -1745 0.2 EHMT2 CCDC82 JRKL GC11M096475 RNA5SP346
GH11J096318 Enhancer 0.8 dbSUPER 47.5 +70.9 70870 0.7 HDAC1 ARNT NFRKB TCF12 GATA2 EGR1 ZBTB2 ZBTB11 ZEB2 ZNF592 CCDC82 MAML2 GC11M096338 GC11P096202
GH11J096305 Enhancer 1.6 FANTOM5 Ensembl ENCODE dbSUPER 18.4 +79.3 79254 10.5 PKNOX1 ATF1 FEZF1 ZNF2 TCF12 FOS MAFF SMARCA4 STAT3 HMBOX1 CCDC82 MAML2 GC11M096338 GC11P096202
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around CCDC82 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the CCDC82 gene promoter:

Genomic Locations for CCDC82 Gene

Genomic Locations for CCDC82 Gene
chr11:96,352,765-96,389,956
(GRCh38/hg38)
Size:
37,192 bases
Orientation:
Minus strand
chr11:96,085,929-96,123,087
(GRCh37/hg19)

Genomic View for CCDC82 Gene

Genes around CCDC82 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CCDC82 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CCDC82 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CCDC82 Gene

Proteins for CCDC82 Gene

  • Protein details for CCDC82 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8N4S0-CCD82_HUMAN
    Recommended name:
    Coiled-coil domain-containing protein 82
    Protein Accession:
    Q8N4S0
    Secondary Accessions:
    • B3KPU7
    • Q8WV71
    • Q9H2Q5
    • Q9H5E3

    Protein attributes for CCDC82 Gene

    Size:
    544 amino acids
    Molecular mass:
    64002 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAB15683.1; Type=Frameshift; Positions=527; Evidence={ECO:0000305};

    Alternative splice isoforms for CCDC82 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for CCDC82 Gene

Post-translational modifications for CCDC82 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for CCDC82 Gene

Domains & Families for CCDC82 Gene

Gene Families for CCDC82 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for CCDC82 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for CCDC82 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CCDC82: view

No data available for UniProtKB/Swiss-Prot for CCDC82 Gene

Function for CCDC82 Gene

Phenotypes From GWAS Catalog for CCDC82 Gene

genes like me logo Genes that share phenotypes with CCDC82: view

Animal Model Products

miRNA for CCDC82 Gene

miRTarBase miRNAs that target CCDC82

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for CCDC82 Gene

Localization for CCDC82 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for CCDC82 gene
Compartment Confidence
nucleus 4
cytosol 2

Subcellular locations from the

Human Protein Atlas (HPA)
  • Cytosol (2)
  • Nucleus (2)
See all subcellular structures

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for CCDC82 Gene

Pathways & Interactions for CCDC82 Gene

SuperPathways for CCDC82 Gene

No Data Available

Interacting Proteins for CCDC82 Gene

Gene Ontology (GO) - Biological Process for CCDC82 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for CCDC82 Gene

Drugs & Compounds for CCDC82 Gene

No Compound Related Data Available

Transcripts for CCDC82 Gene

Unigene Clusters for CCDC82 Gene

Coiled-coil domain containing 82:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for CCDC82 Gene

No ASD Table

Relevant External Links for CCDC82 Gene

GeneLoc Exon Structure for
CCDC82
ECgene alternative splicing isoforms for
CCDC82

Expression for CCDC82 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for CCDC82 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for CCDC82 Gene

This gene is overexpressed in Kidney (53.9).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for CCDC82 Gene



Protein tissue co-expression partners for CCDC82 Gene

NURSA nuclear receptor signaling pathways regulating expression of CCDC82 Gene:

CCDC82

SOURCE GeneReport for Unigene cluster for CCDC82 Gene:

Hs.525088

Evidence on tissue expression from TISSUES for CCDC82 Gene

  • Nervous system(2.8)
  • Pancreas(2.3)
genes like me logo Genes that share expression patterns with CCDC82: view

No data available for mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for CCDC82 Gene

Orthologs for CCDC82 Gene

This gene was present in the common ancestor of chordates.

Orthologs for CCDC82 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia CCDC82 34 33
  • 99.45 (n)
OneToOne
dog
(Canis familiaris)
Mammalia CCDC82 34 33
  • 89.21 (n)
OneToOne
cow
(Bos Taurus)
Mammalia CCDC82 34 33
  • 86.09 (n)
OneToOne
mouse
(Mus musculus)
Mammalia Ccdc82 16 34 33
  • 80.62 (n)
rat
(Rattus norvegicus)
Mammalia Ccdc82 33
  • 79.96 (n)
oppossum
(Monodelphis domestica)
Mammalia CCDC82 34
  • 71 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia CCDC82 34
  • 48 (a)
OneToOne
chicken
(Gallus gallus)
Aves CCDC82 34 33
  • 57.96 (n)
OneToOne
lizard
(Anolis carolinensis)
Reptilia CCDC82 34
  • 39 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia ccdc82 33
  • 54.92 (n)
zebrafish
(Danio rerio)
Actinopterygii ccdc82 34
  • 32 (a)
OneToOne
Species where no ortholog for CCDC82 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CCDC82 Gene

ENSEMBL:
Gene Tree for CCDC82 (if available)
TreeFam:
Gene Tree for CCDC82 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for CCDC82: view image

Paralogs for CCDC82 Gene

No data available for Paralogs for CCDC82 Gene

Variants for CCDC82 Gene

Sequence variations from dbSNP and Humsavar for CCDC82 Gene

SNP ID Clin Chr 11 pos Variation AA Info Type
rs1000079965 -- 96,365,614(-) C/T genic_downstream_transcript_variant, intron_variant
rs1000084043 -- 96,373,671(-) G/C genic_downstream_transcript_variant, intron_variant
rs1000124578 -- 96,368,711(-) A/G/T genic_downstream_transcript_variant, intron_variant
rs1000439490 -- 96,363,052(-) C/T genic_downstream_transcript_variant, intron_variant
rs1000491223 -- 96,356,227(-) A/C/G 3_prime_UTR_variant, genic_downstream_transcript_variant, intron_variant

Variation tolerance for CCDC82 Gene

Residual Variation Intolerance Score: 74.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 9.02; 87.46% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for CCDC82 Gene

Human Gene Mutation Database (HGMD)
CCDC82
SNPedia medical, phenotypic, and genealogical associations of SNPs for
CCDC82

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for CCDC82 Gene

Disorders for CCDC82 Gene

Additional Disease Information for CCDC82

No disorders were found for CCDC82 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CCDC82 Gene

Publications for CCDC82 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 2 3 58
  4. Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning. (PMID: 10931946) Hu RM … Chen JL (Proceedings of the National Academy of Sciences of the United States of America 2000) 3 4 58
  5. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 58

Products for CCDC82 Gene

Sources for CCDC82 Gene

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