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CCDC62 (Coiled-Coil Domain Containing 62) is a Protein Coding gene. Diseases associated with CCDC62 include Postencephalitic Parkinson Disease and Spermatogenic Failure 9. Gene Ontology (GO) annotations related to this gene include nuclear receptor transcription coactivator activity and estrogen receptor binding.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005515 | protein binding | IPI | 19126643 |
GO:0030331 | estrogen receptor binding | IPI | 18563714 |
GO:0030374 | nuclear receptor transcription coactivator activity | IPI | 18563714 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005634 | nucleus | IDA | 19126643 |
GO:0005654 | nucleoplasm | IDA | -- |
GO:0005737 | cytoplasm | IEA | -- |
GO:0005886 | plasma membrane | IDA | -- |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0001835 | blastocyst hatching | IEA | -- |
GO:0045944 | positive regulation of transcription by RNA polymerase II | IPI | 18563714 |
GO:0071392 | cellular response to estradiol stimulus | IDA | 18563714 |
This gene was present in the common ancestor of chordates.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | CCDC62 30 31 |
|
OneToOne | |
Cow (Bos Taurus) |
Mammalia | CCDC62 30 31 |
|
OneToOne | |
Dog (Canis familiaris) |
Mammalia | CCDC62 30 31 |
|
OneToOne | |
Rat (Rattus norvegicus) |
Mammalia | Ccdc62 30 |
|
||
Mouse (Mus musculus) |
Mammalia | Ccdc62 30 17 31 |
|
OneToOne | |
Platypus (Ornithorhynchus anatinus) |
Mammalia | -- 31 |
|
OneToMany | |
-- 31 |
|
OneToMany | |||
-- 31 |
|
OneToMany | |||
Oppossum (Monodelphis domestica) |
Mammalia | CCDC62 31 |
|
OneToOne | |
Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | ccdc62 30 |
|
||
Zebrafish (Danio rerio) |
Actinopterygii | hip1ra 30 31 |
|
OneToOne | |
Sea Squirt (Ciona savignyi) |
Ascidiacea | -- 31 |
|
OneToOne |
SNP ID | Clinical significance and condition | Chr 12 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
rs61735889 | Benign: not provided | 122,801,238(+) |
G/A NM_201435.5(CCDC62):c.1092G>A (p.Gln364=) |
NON_CODING_TRANSCRIPT_VARIANT,SYNONYMOUS | |
rs78361567 | Benign: not provided | 122,798,161(+) |
A/T NM_201435.5(CCDC62):c.938A>T (p.Tyr313Phe) |
MISSENSE_VARIANT,NON_CODING_TRANSCRIPT | |
VAR_035498 | A colorectal cancer sample |
p.Gln31Glu |
|||
rs17855031 | - |
p.Thr394Lys |
|||
rs58131754 | - |
p.Thr141Met |
Variant ID | Type | Subtype | PubMed ID |
---|---|---|---|
nsv1145636 | CNV | deletion | 24896259 |
Disorder | Aliases | PubMed IDs |
---|---|---|
postencephalitic parkinson disease |
|
|
spermatogenic failure 9 |
|
|
parkinson disease, late-onset |
|
|