Aliases for CCDC36 Gene
External Ids for CCDC36 Gene
Previous GeneCards Identifiers for CCDC36 Gene
GeneCards Summary for CCDC36 Gene
CCDC36 (Coiled-Coil Domain Containing 36) is a Protein Coding gene.
UniProtKB/Swiss-Prot for CCDC36 Gene
Required for DNA double-strand breaks (DSBs) formation in unsynapsed regions during meiotic recombination. Probably acts by forming a complex with MEI4 and REC114, which activates DSBs formation in unsynapsed regions, an essential step to ensure completion of synapsis. Not required for HORMAD1 functions in pairing-independent synaptonemal complex formation, ATR recruitment to unsynapsed axes, meiotic silencing of unsynapsed chromatin (MSUC) or meiotic surveillance.