Aliases for CCDC197 Gene

Aliases for CCDC197 Gene

  • Coiled-Coil Domain Containing 197 2 3 5
  • Long Intergenic Non-Protein Coding RNA 521 2 3
  • Coiled-Coil Domain-Containing Protein 197 3 4
  • Uncharacterized Protein CCDC197 3 4
  • LINC00521 3 4
  • C14orf48 3 4
  • Chromosome 14 Open Reading Frame 48 2
  • C14_5713 3
  • CCDC197 5

External Ids for CCDC197 Gene

Previous HGNC Symbols for CCDC197 Gene

  • LINC00521
  • C14orf48

Summaries for CCDC197 Gene

GeneCards Summary for CCDC197 Gene

CCDC197 (Coiled-Coil Domain Containing 197) is a Protein Coding gene.

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for CCDC197 Gene

Genomics for CCDC197 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for CCDC197 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH14J093986 Enhancer 0.8 Ensembl ENCODE dbSUPER 256.6 +0.1 126 1.5 TCF7L2 NFIA HNRNPL EGR2 ZFHX2 CCDC197 NONHSAG015768.2 LOC107984663 lnc-ASB2-1 OTUB2
GH14J094025 Promoter/Enhancer 2 EPDnew Ensembl ENCODE CraniofacialAtlas 16.1 +40.7 40717 4.3 ZBTB10 SP1 MNT MBD2 ZNF217 ZBTB7B ZIC2 HOMEZ ZNF610 THAP11 OTUB2 HSALNG0103342 BTBD7 DDX24 CCDC197 ASB2 IFI27L2 IFI27L1 IFI27 lnc-IFI27L2-3
GH14J094019 Enhancer 1 Ensembl ENCODE 23.8 +34.4 34444 4.7 CEBPA ZNF217 ELF1 CTCF ZIC2 SAP130 CTBP1 RARA KLF9 BCL6 CCDC197 BTBD7 DDX24 IFI27L1 ASB2 SERPINA2 OTUB2 RF00017-1666
GH14J093953 Promoter/Enhancer 1.8 FANTOM5 Ensembl ENCODE dbSUPER 12 -27.2 -27225 13.2 ZBTB10 BCL11A SP1 MXD4 FEZF1 CEBPA NR2C1 ZNF217 POLR2A BHLHE40 BTBD7 SERPINA1 CCDC197 IFI27L2 IFI27 RPSAP4 FAM181A-AS1 ASB2 DDX24 lnc-CCDC197-2
GH14J093927 Promoter/Enhancer 1.1 EPDnew Ensembl CraniofacialAtlas 11.4 -60.2 -60198 1.7 CEBPA CEBPG HLF RFX1 RBFOX2 FAM181A-AS1 FAM181A ASB2 CCDC197
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around CCDC197 on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for CCDC197

Genomic Locations for CCDC197 Gene

Latest Assembly
chr14:93,987,225-94,011,695
(GRCh38/hg38)
Size:
24,471 bases
Orientation:
Plus strand

Previous Assembly
chr14:94,463,616-94,478,041
(GRCh37/hg19 by Entrez Gene)
Size:
14,426 bases
Orientation:
Plus strand

chr14:94,463,616-94,478,040
(GRCh37/hg19 by Ensembl)
Size:
14,425 bases
Orientation:
Plus strand

Genomic View for CCDC197 Gene

Genes around CCDC197 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CCDC197 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CCDC197 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CCDC197 Gene

Proteins for CCDC197 Gene

  • Protein details for CCDC197 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NCU1-CC197_HUMAN
    Recommended name:
    Uncharacterized protein CCDC197
    Protein Accession:
    Q8NCU1
    Secondary Accessions:
    • A0A1B0GVF2
    • Q8N7S1

    Protein attributes for CCDC197 Gene

    Size:
    143 amino acids
    Molecular mass:
    16081 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAC05156.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};

    Alternative splice isoforms for CCDC197 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for CCDC197 Gene

Post-translational modifications for CCDC197 Gene

No Post-translational modifications

Other Protein References for CCDC197 Gene

No data available for DME Specific Peptides for CCDC197 Gene

Domains & Families for CCDC197 Gene

Gene Families for CCDC197 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for CCDC197 Gene

ProtoNet:
genes like me logo Genes that share domains with CCDC197: view

No data available for Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for CCDC197 Gene

Function for CCDC197 Gene

Phenotypes From GWAS Catalog for CCDC197 Gene

Gene Ontology (GO) - Molecular Function for CCDC197 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with CCDC197: view
genes like me logo Genes that share phenotypes with CCDC197: view

miRNA for CCDC197 Gene

miRTarBase miRNAs that target CCDC197

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for CCDC197 Gene

Localization for CCDC197 Gene

Gene Ontology (GO) - Cellular Components for CCDC197 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with CCDC197: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for CCDC197 Gene

Pathways & Interactions for CCDC197 Gene

PathCards logo

SuperPathways for CCDC197 Gene

No Data Available

Gene Ontology (GO) - Biological Process for CCDC197 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for CCDC197 Gene

Drugs & Compounds for CCDC197 Gene

No Compound Related Data Available

Transcripts for CCDC197 Gene

mRNA/cDNA for CCDC197 Gene

2 REFSEQ mRNAs :
7 NCBI additional mRNA sequence :
6 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for CCDC197 Gene

No ASD Table

Relevant External Links for CCDC197 Gene

GeneLoc Exon Structure for
CCDC197

Expression for CCDC197 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for CCDC197

No Expression Related Data Available

Primer products for research

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for CCDC197 Gene

Orthologs for CCDC197 Gene

Evolution for CCDC197 Gene

ENSEMBL:
Gene Tree for CCDC197 (if available)
TreeFam:
Gene Tree for CCDC197 (if available)

No data available for Orthologs for CCDC197 Gene

Paralogs for CCDC197 Gene

No data available for Paralogs for CCDC197 Gene

Variants for CCDC197 Gene

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for CCDC197 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for CCDC197 Gene

Variant ID Type Subtype PubMed ID
nsv1052048 CNV gain 25217958
nsv1405 CNV insertion 18451855
nsv565594 CNV gain 21841781
nsv565617 CNV loss 21841781
nsv565620 CNV loss 21841781

Additional Variant Information for CCDC197 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
CCDC197

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for CCDC197 Gene

Disorders for CCDC197 Gene

Additional Disease Information for CCDC197

No disorders were found for CCDC197 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CCDC197 Gene

Publications for CCDC197 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4
  3. A reference map of the human binary protein interactome. (PMID: 32296183) Luck K … Calderwood MA (Nature 2020) 3
  4. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T … Vidal M (Cell 2014) 3
  5. Towards a proteome-scale map of the human protein-protein interaction network. (PMID: 16189514) Rual JF … Vidal M (Nature 2005) 3

Products for CCDC197 Gene

Sources for CCDC197 Gene