Free for academic non-profit institutions. Other users need a Commercial license

Aliases for CCDC188 Gene

Aliases for CCDC188 Gene

  • Coiled-Coil Domain Containing 188 2 3 5

External Ids for CCDC188 Gene

Summaries for CCDC188 Gene

GeneCards Summary for CCDC188 Gene

CCDC188 (Coiled-Coil Domain Containing 188) is a Protein Coding gene.

Additional gene information for CCDC188 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCDC188 Gene

Genomics for CCDC188 Gene

GeneHancer (GH) Regulatory Elements for CCDC188 Gene

Promoters and enhancers for CCDC188 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH22I020494 Promoter/Enhancer 2.6 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 11.3 -344.6 -344584 2.7 CLOCK FEZF1 YBX1 YY1 SLC30A9 ZNF213 E2F8 ZNF416 ZNF143 ZNF548 MED15 KLHL22 LOC101928824 LZTR1 DGCR8 RPL7AP70 TRMT2A RPL8P5 LOC100420177 THAP7
GH22I019958 Promoter/Enhancer 2.2 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 11.3 +189.8 189784 6.4 HDGF HNRNPUL1 PKNOX1 FOXA2 MLX ARNT ARID4B NEUROD1 SIN3A DMAP1 COMT GC22M019961 LINC01311 LOC100420177 UFD1 RPL7AP70 KLHL22 ENSG00000273343 ZNF74 MED15
GH22I020114 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 9.7 +34.0 34013 4.6 CLOCK MLX ZFP64 FEZF1 DMAP1 SLC30A9 E2F8 ZNF143 ZNF263 SP3 TRMT2A RANBP1 MED15 RPL7AP70 LZTR1 ZDHHC8 UFD1 DGCR8 SCARF2 THAP7
GH22I020153 Enhancer 1.2 FANTOM5 Ensembl ENCODE 14.4 -3.5 -3540 2.1 CTCF MXI1 USF1 RB1 SAP130 ETV1 ARID4B MAX DMAP1 RAD21 CCDC188 ZDHHC8 GC22P020198
GH22I020130 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 7.1 +19.5 19458 2.9 HDGF ATF1 SIN3A DMAP1 ZNF48 GLIS2 ATF7 ZNF263 SP3 SP5 ZDHHC8 TRMT2A CCDC188 ARVCF
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around CCDC188 on UCSC Golden Path with GeneCards custom track

Genomic Locations for CCDC188 Gene

Genomic Locations for CCDC188 Gene
chr22:20,148,417-20,151,259
(GRCh38/hg38)
Size:
2,843 bases
Orientation:
Minus strand
chr22:20,135,950-20,138,399
(GRCh37/hg19)

Genomic View for CCDC188 Gene

Genes around CCDC188 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CCDC188 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CCDC188 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CCDC188 Gene

Proteins for CCDC188 Gene

  • Protein details for CCDC188 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    H7C350-CC188_HUMAN
    Recommended name:
    Coiled-coil domain-containing protein 188
    Protein Accession:
    H7C350

    Protein attributes for CCDC188 Gene

    Size:
    402 amino acids
    Molecular mass:
    43548 Da
    Quaternary structure:
    No Data Available

neXtProt entry for CCDC188 Gene

Post-translational modifications for CCDC188 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CCDC188 Gene

No data available for DME Specific Peptides for CCDC188 Gene

Domains & Families for CCDC188 Gene

Gene Families for CCDC188 Gene

Human Protein Atlas (HPA):
  • Predicted membrane proteins

Protein Domains for CCDC188 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CCDC188: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for CCDC188 Gene

Function for CCDC188 Gene

Phenotypes From GWAS Catalog for CCDC188 Gene

genes like me logo Genes that share phenotypes with CCDC188: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for CCDC188 Gene

Localization for CCDC188 Gene

Subcellular locations from UniProtKB/Swiss-Prot for CCDC188 Gene

Membrane; Single-pass membrane protein.

Subcellular locations from the

Human Protein Atlas (HPA)
  • Nuclear bodies (2)
  • Nucleoplasm (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for CCDC188 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with CCDC188: view

No data available for Subcellular locations from COMPARTMENTS for CCDC188 Gene

Pathways & Interactions for CCDC188 Gene

SuperPathways for CCDC188 Gene

No Data Available

Interacting Proteins for CCDC188 Gene

Gene Ontology (GO) - Biological Process for CCDC188 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for CCDC188 Gene

Drugs & Compounds for CCDC188 Gene

No Compound Related Data Available

Transcripts for CCDC188 Gene

mRNA/cDNA for CCDC188 Gene

(7) REFSEQ mRNAs :
(2) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for CCDC188 Gene

No ASD Table

Relevant External Links for CCDC188 Gene

GeneLoc Exon Structure for
CCDC188
ECgene alternative splicing isoforms for
CCDC188

Expression for CCDC188 Gene

NURSA nuclear receptor signaling pathways regulating expression of CCDC188 Gene:

CCDC188
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for CCDC188 Gene

Orthologs for CCDC188 Gene

This gene was present in the common ancestor of mammals.

Orthologs for CCDC188 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC747175 33
  • 99.31 (n)
-- 34
  • 98 (a)
OneToOne
cow
(Bos Taurus)
Mammalia LOC100848428 33
  • 86.57 (n)
-- 34
  • 66 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia RGD1563782 33
  • 85.68 (n)
dog
(Canis familiaris)
Mammalia LOC100687283 33
  • 84.49 (n)
-- 34
  • 64 (a)
OneToOne
mouse
(Mus musculus)
Mammalia LOC102638083 33
  • 84.04 (n)
Gm7873 34
  • 66 (a)
OneToOne
Ccdc188 16
oppossum
(Monodelphis domestica)
Mammalia -- 34
  • 38 (a)
OneToOne
Species where no ortholog for CCDC188 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for CCDC188 Gene

ENSEMBL:
Gene Tree for CCDC188 (if available)
TreeFam:
Gene Tree for CCDC188 (if available)

Paralogs for CCDC188 Gene

Pseudogenes.org Pseudogenes for CCDC188 Gene

genes like me logo Genes that share paralogs with CCDC188: view

No data available for Paralogs for CCDC188 Gene

Variants for CCDC188 Gene

Sequence variations from dbSNP and Humsavar for CCDC188 Gene

SNP ID Clin Chr 22 pos Variation AA Info Type
rs1000621538 -- 20,150,048(-) C/T coding_sequence_variant, genic_upstream_transcript_variant, intron_variant, synonymous_variant, upstream_transcript_variant
rs1001229463 -- 20,151,356(-) C/T 5_prime_UTR_variant, genic_upstream_transcript_variant, upstream_transcript_variant
rs1002373228 -- 20,147,823(-) G/A downstream_transcript_variant
rs1003223890 -- 20,153,674(-) C/T upstream_transcript_variant
rs1003273565 -- 20,148,522(-) T/G 3_prime_UTR_variant, coding_sequence_variant, downstream_transcript_variant, genic_downstream_transcript_variant, missense_variant, synonymous_variant

Additional Variant Information for CCDC188 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
CCDC188

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for CCDC188 Gene

Disorders for CCDC188 Gene

Additional Disease Information for CCDC188

No disorders were found for CCDC188 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CCDC188 Gene

Publications for CCDC188 Gene

  1. The DNA sequence of human chromosome 22. (PMID: 10591208) Dunham I … O'Brien KP (Nature 1999) 4 58

Products for CCDC188 Gene

Sources for CCDC188 Gene

Content
Loading form....