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Aliases for CCDC179 Gene

Aliases for CCDC179 Gene

  • Coiled-Coil Domain Containing 179 2 3 5
  • Coiled-Coil Domain-Containing Protein 179 3

External Ids for CCDC179 Gene

Summaries for CCDC179 Gene

GeneCards Summary for CCDC179 Gene

CCDC179 (Coiled-Coil Domain Containing 179) is a Protein Coding gene.

Additional gene information for CCDC179 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCDC179 Gene

Genomics for CCDC179 Gene

GeneHancer (GH) Regulatory Elements for CCDC179 Gene

Promoters and enhancers for CCDC179 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH11J022875 Enhancer 0.7 ENCODE 0.4 -15.6 -15584 0.2 CTCF FOXA2 TEAD4 RAD21 RFX5 TEAD3 GATA3 SMC3 ZNF143 RCOR1 SVIP CCDC179 ENSG00000246225 GC11P023099
GH11J023080 Enhancer 0.6 ENCODE 0.1 -219.0 -219014 0.2 RB1 TRIM22 EBF1 BATF ZNF592 ZNF217 IKZF1 ZNF24 FOS ATF7 GC11P023099 CCDC179
GH11J023078 Enhancer 0.6 ENCODE 0.1 -218.3 -218272 1.3 JUN TRIM22 EBF1 BMI1 MEF2B BATF ZNF217 JUND IKZF1 NBN GC11P023099 CCDC179
GH11J023079 Enhancer 0.5 ENCODE 0.1 -219.2 -219244 0.2 ZNF217 RB1 TRIM22 EBF1 IKZF2 ZNF592 GC11P023099 CCDC179
GH11J022935 Enhancer 0.2 FANTOM5 0.2 -75.0 -75012 0.4 LOC105376592 CCDC179 ENSG00000246225 GC11P023099
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around CCDC179 on UCSC Golden Path with GeneCards custom track

Genomic Locations for CCDC179 Gene

Genomic Locations for CCDC179 Gene
chr11:22,846,922-22,860,486
(GRCh38/hg38)
Size:
13,565 bases
Orientation:
Minus strand
chr11:22,868,468-22,881,972
(GRCh37/hg19)

Genomic View for CCDC179 Gene

Genes around CCDC179 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CCDC179 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CCDC179 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CCDC179 Gene

Proteins for CCDC179 Gene

  • Protein details for CCDC179 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    H3BU77-CC179_HUMAN
    Recommended name:
    Coiled-coil domain-containing protein 179
    Protein Accession:
    H3BU77

    Protein attributes for CCDC179 Gene

    Size:
    68 amino acids
    Molecular mass:
    8104 Da
    Quaternary structure:
    No Data Available

neXtProt entry for CCDC179 Gene

Post-translational modifications for CCDC179 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CCDC179 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for CCDC179 Gene

Domains & Families for CCDC179 Gene

Gene Families for CCDC179 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for CCDC179 Gene

ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CCDC179: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for CCDC179 Gene

Function for CCDC179 Gene

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for CCDC179

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for CCDC179 Gene

Localization for CCDC179 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for CCDC179 Gene

Pathways & Interactions for CCDC179 Gene

SuperPathways for CCDC179 Gene

No Data Available

Interacting Proteins for CCDC179 Gene

Gene Ontology (GO) - Biological Process for CCDC179 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for CCDC179 Gene

Drugs & Compounds for CCDC179 Gene

No Compound Related Data Available

Transcripts for CCDC179 Gene

mRNA/cDNA for CCDC179 Gene

(0) Additional mRNA sequences :
-
(3) REFSEQ mRNAs :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for CCDC179 Gene

Coiled-coil domain containing 179:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for CCDC179

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for CCDC179 Gene

No ASD Table

Relevant External Links for CCDC179 Gene

GeneLoc Exon Structure for
CCDC179
ECgene alternative splicing isoforms for
CCDC179

Expression for CCDC179 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for CCDC179 Gene

mRNA differential expression in normal tissues according to GTEx for CCDC179 Gene

This gene is overexpressed in Testis (x51.9).

NURSA nuclear receptor signaling pathways regulating expression of CCDC179 Gene:

CCDC179

SOURCE GeneReport for Unigene cluster for CCDC179 Gene:

Hs.555029
genes like me logo Genes that share expression patterns with CCDC179: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for CCDC179 Gene

Orthologs for CCDC179 Gene

This gene was present in the common ancestor of mammals.

Orthologs for CCDC179 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC100610029 33
  • 94.87 (n)
dog
(Canis familiaris)
Mammalia CCDC179 34
  • 64 (a)
OneToOne
mouse
(Mus musculus)
Mammalia 1700015G11Rik 34
  • 63 (a)
OneToOne
Species where no ortholog for CCDC179 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for CCDC179 Gene

ENSEMBL:
Gene Tree for CCDC179 (if available)
TreeFam:
Gene Tree for CCDC179 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for CCDC179: view image

Paralogs for CCDC179 Gene

No data available for Paralogs for CCDC179 Gene

Variants for CCDC179 Gene

Sequence variations from dbSNP and Humsavar for CCDC179 Gene

SNP ID Clin Chr 11 pos Variation AA Info Type
rs1000005473 -- 22,849,978(-) C/T genic_downstream_transcript_variant, intron_variant
rs1000413575 -- 22,858,461(-) C/G intron_variant
rs1000427996 -- 22,856,120(-) A/G 3_prime_UTR_variant, intron_variant
rs1000456996 -- 22,862,948(-) C/T upstream_transcript_variant
rs1000695709 -- 22,861,054(-) T/C upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for CCDC179 Gene

Variant ID Type Subtype PubMed ID
dgv336e212 CNV loss 25503493
esv3625623 CNV gain 21293372
esv3625625 CNV gain 21293372
nsv1040326 CNV loss 25217958
nsv1046773 CNV loss 25217958
nsv1049802 CNV gain 25217958
nsv522782 CNV loss 19592680
nsv523451 CNV loss 19592680
nsv524283 CNV loss 19592680

Variation tolerance for CCDC179 Gene

Gene Damage Index Score: 11.61; 93.09% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for CCDC179 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
CCDC179

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CCDC179 Gene

Disorders for CCDC179 Gene

Additional Disease Information for CCDC179

No disorders were found for CCDC179 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CCDC179 Gene

Publications for CCDC179 Gene

  1. Human chromosome 11 DNA sequence and analysis including novel gene identification. (PMID: 16554811) Taylor TD … Sakaki Y (Nature 2006) 4 58

Products for CCDC179 Gene

Sources for CCDC179 Gene

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