Aliases for CCDC166 Gene

Aliases for CCDC166 Gene

  • Coiled-Coil Domain Containing 166 2 3 5
  • Coiled-Coil Domain-Containing Protein 166 3 4
  • CCDC166 5

External Ids for CCDC166 Gene

Previous GeneCards Identifiers for CCDC166 Gene

  • GC08M144789

Summaries for CCDC166 Gene

GeneCards Summary for CCDC166 Gene

CCDC166 (Coiled-Coil Domain Containing 166) is a Protein Coding gene. An important paralog of this gene is BBOF1.

Additional gene information for CCDC166 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for CCDC166 Gene

Genomics for CCDC166 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for CCDC166 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around CCDC166 on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for CCDC166

Genomic Locations for CCDC166 Gene

Genomic Locations for CCDC166 Gene
chr8:143,706,694-143,708,109
(GRCh38/hg38)
Size:
1,416 bases
Orientation:
Minus strand
chr8:144,788,864-144,790,279
(GRCh37/hg19)
Size:
1,416 bases
Orientation:
Minus strand

Genomic View for CCDC166 Gene

Genes around CCDC166 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CCDC166 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CCDC166 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CCDC166 Gene

Proteins for CCDC166 Gene

  • Protein details for CCDC166 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P0CW27-CC166_HUMAN
    Recommended name:
    Coiled-coil domain-containing protein 166
    Protein Accession:
    P0CW27

    Protein attributes for CCDC166 Gene

    Size:
    439 amino acids
    Molecular mass:
    48709 Da
    Quaternary structure:
    No Data Available

neXtProt entry for CCDC166 Gene

Post-translational modifications for CCDC166 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CCDC166 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for CCDC166 Gene

Domains & Families for CCDC166 Gene

Gene Families for CCDC166 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for CCDC166 Gene

InterPro:
ProtoNet:
genes like me logo Genes that share domains with CCDC166: view

No data available for Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for CCDC166 Gene

Function for CCDC166 Gene

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for CCDC166

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for CCDC166 Gene

Localization for CCDC166 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for CCDC166 gene
Compartment Confidence
peroxisome 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for CCDC166 Gene

Pathways & Interactions for CCDC166 Gene

PathCards logo

SuperPathways for CCDC166 Gene

No Data Available

Interacting Proteins for CCDC166 Gene

Gene Ontology (GO) - Biological Process for CCDC166 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for CCDC166 Gene

Drugs & Compounds for CCDC166 Gene

No Compound Related Data Available

Transcripts for CCDC166 Gene

mRNA/cDNA for CCDC166 Gene

1 REFSEQ mRNAs :
1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for CCDC166

Alternative Splicing Database (ASD) splice patterns (SP) for CCDC166 Gene

No ASD Table

Relevant External Links for CCDC166 Gene

GeneLoc Exon Structure for
CCDC166

Expression for CCDC166 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for CCDC166 Gene

mRNA differential expression in normal tissues according to GTEx for CCDC166 Gene

This gene is overexpressed in Testis (x39.9).

Protein differential expression in normal tissues from HIPED for CCDC166 Gene

This gene is overexpressed in Nasal epithelium (66.8).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for CCDC166 Gene



Protein tissue co-expression partners for CCDC166 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for CCDC166

SOURCE GeneReport for Unigene cluster for CCDC166 Gene:

Hs.730002
genes like me logo Genes that share expression patterns with CCDC166: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for CCDC166 Gene

Orthologs for CCDC166 Gene

This gene was present in the common ancestor of chordates.

Orthologs for CCDC166 Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia CCDC166 30
  • 99.12 (n)
Dog
(Canis familiaris)
Mammalia CCDC166 30
  • 79.44 (n)
Cow
(Bos Taurus)
Mammalia CCDC166 30 31
  • 76.37 (n)
OneToOne
Mouse
(Mus musculus)
Mammalia Ccdc166 30 17 31
  • 71.16 (n)
OneToOne
Rat
(Rattus norvegicus)
Mammalia Ccdc166 30
  • 70.28 (n)
Oppossum
(Monodelphis domestica)
Mammalia CCDC166 31
  • 52 (a)
OneToOne
Chicken
(Gallus gallus)
Aves LOC100859066 30
  • 53.22 (n)
Lizard
(Anolis carolinensis)
Reptilia CCDC166 31
  • 49 (a)
OneToOne
Tropical Clawed Frog
(Silurana tropicalis)
Amphibia LOC101731877 30
  • 55.96 (n)
Zebrafish
(Danio rerio)
Actinopterygii LOC100538228 30
  • 42.88 (n)
Species where no ortholog for CCDC166 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Platypus (Ornithorhynchus anatinus)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)

Evolution for CCDC166 Gene

ENSEMBL:
Gene Tree for CCDC166 (if available)
TreeFam:
Gene Tree for CCDC166 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for CCDC166: view image

Paralogs for CCDC166 Gene

Paralogs for CCDC166 Gene

genes like me logo Genes that share paralogs with CCDC166: view

Variants for CCDC166 Gene

Additional dbSNP identifiers (rs#s) for CCDC166 Gene

Structural Variations from Database of Genomic Variants (DGV) for CCDC166 Gene

Variant ID Type Subtype PubMed ID
nsv466007 CNV loss 19166990
nsv519816 CNV loss 19592680
nsv612893 CNV loss 21841781

Variation tolerance for CCDC166 Gene

Gene Damage Index Score: 5.38; 71.03% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for CCDC166 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
CCDC166

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for CCDC166 Gene

Disorders for CCDC166 Gene

No disorders were found for CCDC166 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CCDC166 Gene

Publications for CCDC166 Gene

  1. DNA sequence and analysis of human chromosome 8. (PMID: 16421571) Nusbaum C … Lander ES (Nature 2006) 4

Products for CCDC166 Gene

Sources for CCDC166 Gene