Aliases for CCDC159 Gene
Aliases for CCDC159 Gene
External Ids for CCDC159 Gene
- HGNC: 26996
- Entrez Gene: 126075
- Ensembl: ENSG00000183401
- UniProtKB: P0C7I6
Previous GeneCards Identifiers for CCDC159 Gene
- GC19P011321
- GC19P011455
- GC19P011033
Summaries for CCDC159 Gene
GeneCards Summary for CCDC159 Gene
CCDC159 (Coiled-Coil Domain Containing 159) is a Protein Coding gene.
Additional gene information for CCDC159 Gene
No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCDC159 Gene
Genomics for CCDC159 Gene
GeneHancer (GH) Regulatory Elements for CCDC159 Gene
Promoters and enhancers for CCDC159 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)
GeneHancers around CCDC159 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Locations for CCDC159 Gene
Genomic Locations for CCDC159 Gene
- chr19:11,344,684-11,354,944
- (GRCh38/hg38)
- Size:
- 10,261 bases
- Orientation:
- Plus strand
- chr19:11,455,360-11,465,620
- (GRCh37/hg19)
- Size:
- 10,261 bases
- Orientation:
- Plus strand
Genomic View for CCDC159 Gene
Genes around CCDC159 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 19p13.2 by Entrez Gene
- 19p13.2 by HGNC
- 19p13.2 by Ensembl
CCDC159 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for CCDC159 Gene
Proteins for CCDC159 Gene
-
Protein details for CCDC159 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P0C7I6-CC159_HUMAN
- Recommended name:
- Coiled-coil domain-containing protein 159
- Protein Accession:
- P0C7I6
- B4DEG3
- B4DWR8
- B4E133
- B7ZAM4
Protein attributes for CCDC159 Gene
- Size:
- 297 amino acids
- Molecular mass:
- 33695 Da
- Quaternary structure:
- No Data Available
- SequenceCaution:
-
- Sequence=BAG63130.1; Type=Miscellaneous discrepancy; Note=Intron retention.; Evidence={ECO:0000305}; Sequence=BC038439; Type=Miscellaneous discrepancy; Note=Cloning artifact.; Evidence={ECO:0000305};
Post-translational modifications for CCDC159 Gene
Other Protein References for CCDC159 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for CCDC159
- Novus Biologicals Antibodies for CCDC159
- Invitrogen Antibodies for CCDC159 (AFLGC-CCDC159)
- Search GeneTex for Antibodies for CCDC159
-
Boster Bio Antibodies for CCDC159
Protein Products
-
OriGene Purified Proteins for CCDC159
- Search Origene for MassSpec and Protein Over-expression Lysates for CCDC159
- Origene Custom Protein Services for CCDC159
- Search GeneTex for Proteins for CCDC159
Assay Products
No data available for DME Specific Peptides for CCDC159 Gene
Domains & Families for CCDC159 Gene
Gene Families for CCDC159 Gene
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Protein Domains for CCDC159 Gene
- ProtoNet:
Suggested Antigen Peptide Sequences for CCDC159 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
No data available for UniProtKB/Swiss-Prot for CCDC159 Gene
Function for CCDC159 Gene
Phenotypes From GWAS Catalog for CCDC159 Gene
Phenotypes for CCDC159 Gene
- MGI mutant phenotypes for CCDC159:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for CCDC159:
Animal Models for CCDC159 Gene
- MGI Knock Outs for CCDC159:
-
- Ccdc159 Ccdc159<tm1a(KOMP)Wtsi>
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for CCDC159
-
CRISPR Products
-
OriGene CRISPR knockouts for CCDC159
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for CCDC159
- genomics-online: gRNA clones - Search results for 62 available CCDC159 gene related products
- Overview of 62 available CCDC159 gene related products
- Applied Biological Materials CRISPR for CCDC159
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for CCDC159
- GenScript: Design CRISPR guide RNA sequences for CCDC159
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for CCDC159
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- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for CCDC159
- genomics-online: shRNA clones - Search results for 62 available CCDC159 gene related products
- Overview of 62 available CCDC159 gene related products
Clone Products
- Sino Biological Human cDNA Clone for CCDC159
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for CCDC159
- Applied Biological Materials Clones for CCDC159
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for CCDC159
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , miRNA , Transcription Factor Targets and HOMER Transcription for CCDC159 Gene
Localization for CCDC159 Gene
| Compartment | Confidence |
|---|---|
| nucleus | 4 |
| cytosol | 3 |
| extracellular | 2 |
| mitochondrion | 1 |
- Cytosol (2)
- Nuclear bodies (2)
- Nucleoplasm (2)
No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for CCDC159 Gene
Pathways & Interactions for CCDC159 Gene
No Data Available
Interacting Proteins for CCDC159 Gene
No data available for Pathways by source and SIGNOR curated interactions for CCDC159 Gene
Transcripts for CCDC159 Gene
mRNA/cDNA for CCDC159 Gene
- (14) REFSEQ mRNAs :
- (1) Additional mRNA sequences :
- (142) Selected AceView cDNA sequences:
- (20) Ensembl transcripts including schematic representations, and UCSC links where relevant :
-
- ENST00000589186 555 bps (uc060tqs.1)
- ENST00000587100 768 bps (uc060tqt.1)
- ENST00000588790 1408 bps (uc010xlt.3)
- ENST00000590919 396 bps (uc060tqv.1)
- ENST00000588821 981 bps (uc060tqx.1)
Unigene Clusters for CCDC159 Gene
CRISPR Products
-
OriGene CRISPR knockouts for CCDC159
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for CCDC159
- genomics-online: gRNA clones - Search results for 62 available CCDC159 gene related products
- Overview of 62 available CCDC159 gene related products
- Applied Biological Materials CRISPR for CCDC159
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for CCDC159
- GenScript: Design CRISPR guide RNA sequences for CCDC159
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for CCDC159
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- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for CCDC159
- genomics-online: shRNA clones - Search results for 62 available CCDC159 gene related products
- Overview of 62 available CCDC159 gene related products
Clone Products
- Sino Biological Human cDNA Clone for CCDC159
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for CCDC159
- Applied Biological Materials Clones for CCDC159
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3a | · | 3b | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | · | 6c | · | 6d | ^ | 7a | · | 7b | · | 7c | · | 7d | ^ | 8a | · | 8b | ^ | 9a | · | 9b | ^ | 10 | ^ | 11 | ^ | 12 |
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| SP6: | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||
| SP7: | - | ||||||||||||||||||||||||||||||||||||||||||||
| SP8: | - | - | |||||||||||||||||||||||||||||||||||||||||||
| SP9: |
Expression for CCDC159 Gene
NURSA nuclear receptor signaling pathways regulating expression of CCDC159 Gene:
CCDC159SOURCE GeneReport for Unigene cluster for CCDC159 Gene:
Hs.631636Primer Products
-
OriGene qPCR primer pairs for CCDC159
- genomics-online: primer clones - Search results for 62 available CCDC159 gene related products
- Overview of 62 available CCDC159 gene related products
Gene Expression Assay Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for CCDC159 Gene
Orthologs for CCDC159 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | CCDC159 34 33 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | CCDC159 34 33 |
|
OneToOne | |
| cow (Bos Taurus) |
Mammalia | CCDC159 34 33 |
|
OneToOne | |
| mouse (Mus musculus) |
Mammalia | Ccdc159 16 34 33 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Ccdc159 33 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | CCDC159 34 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | CCDC159 34 |
|
OneToOne | |
| lizard (Anolis carolinensis) |
Reptilia | CCDC159 34 |
|
OneToOne |
- Species where no ortholog for CCDC159 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
- zebrafish (Danio rerio)
Evolution for CCDC159 Gene
- ENSEMBL:
- Gene Tree for CCDC159 (if available)
- TreeFam:
- Gene Tree for CCDC159 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for CCDC159: view image
Paralogs for CCDC159 Gene
No data available for Paralogs for CCDC159 Gene
Variants for CCDC159 Gene
| SNP ID | Clin | Chr 19 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000172972 | -- | 11,354,992(+) | C/A | downstream_transcript_variant | |
| rs1000212178 | -- | 11,351,302(+) | C/A/T | intron_variant | |
| rs1000270331 | -- | 11,344,732(+) | G/C | upstream_transcript_variant | |
| rs1000949909 | -- | 11,349,770(+) | C/T | intron_variant | |
| rs1001168866 | -- | 11,352,817(+) | G/A | intron_variant |
Residual Variation Intolerance Score:
70.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
6.77;
78.98% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for CCDC159 Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CCDC159 Gene
Disorders for CCDC159 Gene
Additional Disease Information for CCDC159
No disorders were found for CCDC159 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CCDC159 Gene
Publications for CCDC159 Gene
- The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J … Lucas SM (Nature 2004) 3 4 58
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
- A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration. (PMID: 16713569) Lim J … Zoghbi HY (Cell 2006) 3 58
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 4 58
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 58
Products for CCDC159 Gene
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- Custom Antibody ServicesOriGene Antibodies for CCDC159
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- Invitrogen Antibodies for CCDC159 (AFLGC-CCDC159)
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- Overview of 62 available CCDC159 gene related products
- Browse GeneCopoeia Cell Lines
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- Boster Bio Antibodies for CCDC159
- Browse Boster Bio ELISA Kits
Sources for CCDC159 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew
- (158) Applied Biosystems
- (159) GlyConnect
- (160) Aminode
- (161) GeneCopoeia
- (162) GPS-Prot
- (163) RNACentral
- (164) LncRNADisease
- (165) LOVD
- (166) miR2Disease
- (167) DiseaseEnhancer
- (168) Boster Bio
- (169) Biorbyt