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Aliases for CCDC152 Gene

Aliases for CCDC152 Gene

  • Coiled-Coil Domain Containing 152 2 3 5
  • Coiled-Coil Domain-Containing Protein 152 3
  • CH5400 3

External Ids for CCDC152 Gene

Previous GeneCards Identifiers for CCDC152 Gene

  • GC05P042793

Summaries for CCDC152 Gene

GeneCards Summary for CCDC152 Gene

CCDC152 (Coiled-Coil Domain Containing 152) is a Protein Coding gene.

Additional gene information for CCDC152 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCDC152 Gene

Genomics for CCDC152 Gene

GeneHancer (GH) Regulatory Elements for CCDC152 Gene

Promoters and enhancers for CCDC152 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH05I042756 Promoter 1.6 EPDnew Ensembl 570.7 +0.3 300 1 MEIS2 TAF9B RB1 ETV1 ZBTB40 ETS1 CHAMP1 DIDO1 PHF20 POLR2A CCDC152 GHR GC05M042801
GH05I042807 Promoter/Enhancer 2.2 EPDnew Ensembl ENCODE 19.8 +54.0 53989 7.1 FOXA2 MLX ZFP64 ARID4B DMAP1 YY1 POLR2B PAF1 SP3 MXD4 SELENOP CCDC152 PPIAP77 GHR LOC648987 ENSG00000272234
GH05I042850 Enhancer 0.8 ENCODE 14.4 +96.8 96762 5.3 ELF3 FOXA2 FEZF1 RAD21 RARA YY1 TCF12 ZNF350 MIXL1 RXRA CCDC152 SELENOP PPIAP77 GHR ENSG00000272234
GH05I042806 Enhancer 0.5 ENCODE 20.3 +49.6 49612 0.6 ZFHX2 POLR2A ZNF512 EGR2 ENSG00000272234 CCDC152 SELENOP PPIAP77 GHR
GH05I042621 Enhancer 0.8 Ensembl dbSUPER 11.3 -135.1 -135100 1.4 SMAD1 NFIB TEAD2 MAX CEBPG GATA3 NFIC LCORL ATF3 CCDC152 GC05M042543 PIR62948 GHR
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around CCDC152 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the CCDC152 gene promoter:

Genomic Locations for CCDC152 Gene

Genomic Locations for CCDC152 Gene
chr5:42,756,801-42,802,437
(GRCh38/hg38)
Size:
45,637 bases
Orientation:
Plus strand
chr5:42,756,903-42,802,539
(GRCh37/hg19)

Genomic View for CCDC152 Gene

Genes around CCDC152 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CCDC152 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CCDC152 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CCDC152 Gene

Proteins for CCDC152 Gene

  • Protein details for CCDC152 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q4G0S7-CC152_HUMAN
    Recommended name:
    Coiled-coil domain-containing protein 152
    Protein Accession:
    Q4G0S7
    Secondary Accessions:
    • B3KXI4
    • B4E0P7
    • Q5BLP6

    Protein attributes for CCDC152 Gene

    Size:
    254 amino acids
    Molecular mass:
    29979 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAH39102.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};

    Alternative splice isoforms for CCDC152 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for CCDC152 Gene

Post-translational modifications for CCDC152 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CCDC152 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for CCDC152 Gene

Domains & Families for CCDC152 Gene

Gene Families for CCDC152 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for CCDC152 Gene

ProtoNet:

Suggested Antigen Peptide Sequences for CCDC152 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CCDC152: view

No data available for UniProtKB/Swiss-Prot for CCDC152 Gene

Function for CCDC152 Gene

Phenotypes From GWAS Catalog for CCDC152 Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for CCDC152 Gene

Localization for CCDC152 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for CCDC152 gene
Compartment Confidence
nucleus 4
cytosol 3

Subcellular locations from the

Human Protein Atlas (HPA)
  • Cytosol (2)
  • Nucleoplasm (2)
See all subcellular structures

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for CCDC152 Gene

Pathways & Interactions for CCDC152 Gene

SuperPathways for CCDC152 Gene

No Data Available

Interacting Proteins for CCDC152 Gene

Selected Interacting proteins: Q4G0S7-CC152_HUMAN for CCDC152 Gene via IID

Symbol External ID(s) Details
FAM161B
PRR11

Gene Ontology (GO) - Biological Process for CCDC152 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for CCDC152 Gene

Drugs & Compounds for CCDC152 Gene

No Compound Related Data Available

Transcripts for CCDC152 Gene

mRNA/cDNA for CCDC152 Gene

(1) REFSEQ mRNAs :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for CCDC152 Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4a · 4b ^ 5a · 5b ^ 6 ^ 7a · 7b ^ 8a · 8b ^ 9 ^ 10a · 10b ^ 11a · 11b · 11c · 11d · 11e · 11f · 11g · 11h · 11i
SP1: - - - - - -
SP2: - - - - - -
SP3: - - - - - - - -
SP4: - - - - - - - -
SP5: - - - - -
SP6: - - - - - - -
SP7: - - - - - - -
SP8: - - - - - - - - -
SP9: - - - -
SP10: - - - - - - - -
SP11: - - - -
SP12: - - - - - - - - - - -
SP13: - - -
SP14: -
SP15: - - - - - - - -

Relevant External Links for CCDC152 Gene

GeneLoc Exon Structure for
CCDC152
ECgene alternative splicing isoforms for
CCDC152

Expression for CCDC152 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for CCDC152 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for CCDC152 Gene

This gene is overexpressed in Tonsil (29.7), Oral epithelium (20.4), and Monocytes (11.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for CCDC152 Gene



NURSA nuclear receptor signaling pathways regulating expression of CCDC152 Gene:

CCDC152

mRNA Expression by UniProt/SwissProt for CCDC152 Gene:

Q4G0S7-CC152_HUMAN
Tissue specificity: Detected in stomach.
genes like me logo Genes that share expression patterns with CCDC152: view

No data available for mRNA differential expression in normal tissues , Protein tissue co-expression partners , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for CCDC152 Gene

Orthologs for CCDC152 Gene

This gene was present in the common ancestor of chordates.

Orthologs for CCDC152 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia CCDC152 33 34
  • 99.61 (n)
dog
(Canis familiaris)
Mammalia CCDC152 33 34
  • 90.68 (n)
cow
(Bos Taurus)
Mammalia CCDC152 33 34
  • 88.19 (n)
mouse
(Mus musculus)
Mammalia Ccdc152 33 16 34
  • 83.73 (n)
rat
(Rattus norvegicus)
Mammalia Ccdc152 33
  • 83.33 (n)
oppossum
(Monodelphis domestica)
Mammalia CCDC152 34
  • 68 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia CCDC152 34
  • 43 (a)
OneToOne
chicken
(Gallus gallus)
Aves CCDC152 33 34
  • 70.19 (n)
lizard
(Anolis carolinensis)
Reptilia CCDC152 34
  • 59 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia ccdc152 33
  • 61.25 (n)
zebrafish
(Danio rerio)
Actinopterygii LOC101886863 33
  • 54.21 (n)
Species where no ortholog for CCDC152 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CCDC152 Gene

ENSEMBL:
Gene Tree for CCDC152 (if available)
TreeFam:
Gene Tree for CCDC152 (if available)

Paralogs for CCDC152 Gene

No data available for Paralogs for CCDC152 Gene

Variants for CCDC152 Gene

Sequence variations from dbSNP and Humsavar for CCDC152 Gene

SNP ID Clin Chr 05 pos Variation AA Info Type
rs1000043725 -- 42,780,216(+) C/T intron_variant
rs1000082216 -- 42,790,035(+) A/G intron_variant
rs1000135604 -- 42,767,698(+) C/A intron_variant
rs1000148916 -- 42,776,392(+) A/G intron_variant
rs1000276238 -- 42,796,119(+) A/T intron_variant

Structural Variations from Database of Genomic Variants (DGV) for CCDC152 Gene

Variant ID Type Subtype PubMed ID
dgv5637n100 CNV gain 25217958
esv3604874 CNV gain 21293372
nsv462126 CNV gain 19166990
nsv523033 CNV gain 19592680
nsv597886 CNV gain 21841781
nsv597925 CNV gain 21841781

Variation tolerance for CCDC152 Gene

Gene Damage Index Score: 1.75; 33.17% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for CCDC152 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
CCDC152

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CCDC152 Gene

Disorders for CCDC152 Gene

Additional Disease Information for CCDC152

No disorders were found for CCDC152 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CCDC152 Gene

Publications for CCDC152 Gene

  1. Comparative gene finding in chicken indicates that we are closing in on the set of multi-exonic widely expressed human genes. (PMID: 15809229) Castelo R … Eyras E (Nucleic acids research 2005) 3 4 58
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 4 58
  3. The DNA sequence and comparative analysis of human chromosome 5. (PMID: 15372022) Schmutz J … Rubin EM (Nature 2004) 4 58
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 4 58
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 58

Products for CCDC152 Gene

Sources for CCDC152 Gene

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