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Aliases for CCDC150 Gene

Aliases for CCDC150 Gene

  • Coiled-Coil Domain Containing 150 2 3 5
  • Coiled-Coil Domain-Containing Protein 150 3

External Ids for CCDC150 Gene

Previous GeneCards Identifiers for CCDC150 Gene

  • GC02P197214
  • GC02P197504
  • GC02P189356

Summaries for CCDC150 Gene

GeneCards Summary for CCDC150 Gene

CCDC150 (Coiled-Coil Domain Containing 150) is a Protein Coding gene.

Additional gene information for CCDC150 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCDC150 Gene

Genomics for CCDC150 Gene

GeneHancer (GH) Regulatory Elements for CCDC150 Gene

Promoters and enhancers for CCDC150 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH02J196639 Promoter/Enhancer 1.5 Ensembl ENCODE 656.2 +0.5 503 2 PKNOX1 SMAD1 MLX ZFP64 ARID4B SIN3A DMAP1 ZNF2 YY1 SLC30A9 CCDC150 LOC105373823 SF3B1 NPM1P46 GTF3C3 LOC101927482 C2orf66 ANKRD44 ENSG00000252923 GC02M196687
GH02J196718 Promoter/Enhancer 1.5 EPDnew Ensembl ENCODE 655.7 +79.8 79816 1.8 FOXA2 TAF9B ARID4B SIN3A DMAP1 THRB ZNF48 RAD21 ETS1 ATF7 CCDC150 LOC100130452 GTF3C3
GH02J196713 Promoter 0.6 EPDnew 650.2 +73.6 73561 0.1 CREB1 LOC100130452 CCDC150 GTF3C3
GH02J196600 Enhancer 1.3 FANTOM5 Ensembl ENCODE 10.8 -37.8 -37830 2 PKNOX1 CLOCK NEUROD1 SIN3A BMI1 ZBTB40 RAD21 RFX5 RCOR1 FOS CCDC150 HECW2 LOC105373823
GH02J196696 Enhancer 0.8 Ensembl ENCODE 15.9 +57.1 57078 1 JUN CEBPB CEBPG EP300 ZNF335 FOSL1 GATA3 JUND SMARCA4 CEBPA CCDC150 ANKRD44 GC02M196687 ENSG00000252923 LOC100130452
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around CCDC150 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the CCDC150 gene promoter:
  • FOXO3b
  • FOXO3a
  • FOXO3
  • Pax-5
  • Ik-2
  • RORalpha2
  • TBP
  • POU2F1c
  • POU2F1b
  • POU2F1a

Genomic Locations for CCDC150 Gene

Genomic Locations for CCDC150 Gene
123,937 bases
Plus strand
123,937 bases
Plus strand

Genomic View for CCDC150 Gene

Genes around CCDC150 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CCDC150 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CCDC150 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CCDC150 Gene

Proteins for CCDC150 Gene

  • Protein details for CCDC150 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Coiled-coil domain-containing protein 150
    Protein Accession:
    Secondary Accessions:
    • Q6P5U6
    • Q6P663
    • Q8N8V5

    Protein attributes for CCDC150 Gene

    1101 amino acids
    Molecular mass:
    128761 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAH62658.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-A sequence.; Evidence={ECO:0000305};

    Alternative splice isoforms for CCDC150 Gene


neXtProt entry for CCDC150 Gene

Post-translational modifications for CCDC150 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for CCDC150 Gene

Domains & Families for CCDC150 Gene

Gene Families for CCDC150 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for CCDC150 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CCDC150: view

No data available for UniProtKB/Swiss-Prot for CCDC150 Gene

Function for CCDC150 Gene

Gene Ontology (GO) - Molecular Function for CCDC150 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with CCDC150: view
genes like me logo Genes that share phenotypes with CCDC150: view

Animal Model Products

miRNA for CCDC150 Gene

miRTarBase miRNAs that target CCDC150

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for CCDC150 Gene

Localization for CCDC150 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for CCDC150 gene
Compartment Confidence
nucleus 3
cytosol 2

Subcellular locations from the

Human Protein Atlas (HPA)

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for CCDC150 Gene

Pathways & Interactions for CCDC150 Gene

SuperPathways for CCDC150 Gene

No Data Available

Interacting Proteins for CCDC150 Gene

Gene Ontology (GO) - Biological Process for CCDC150 Gene


No data available for Pathways by source and SIGNOR curated interactions for CCDC150 Gene

Drugs & Compounds for CCDC150 Gene

No Compound Related Data Available

Transcripts for CCDC150 Gene

Unigene Clusters for CCDC150 Gene

Coiled-coil domain containing 150:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for CCDC150 Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5a · 5b · 5c ^ 6 ^ 7 ^ 8 ^ 9
SP1: -
SP2: - - - -
SP4: -

Relevant External Links for CCDC150 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for CCDC150 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for CCDC150 Gene

mRNA differential expression in normal tissues according to GTEx for CCDC150 Gene

This gene is overexpressed in Testis (x17.1).

Protein differential expression in normal tissues from HIPED for CCDC150 Gene

This gene is overexpressed in Vitreous humor (29.4), Bone marrow stromal cell (28.7), and Cardia (7.2).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for CCDC150 Gene

NURSA nuclear receptor signaling pathways regulating expression of CCDC150 Gene:


SOURCE GeneReport for Unigene cluster for CCDC150 Gene:

genes like me logo Genes that share expression patterns with CCDC150: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for CCDC150 Gene

Orthologs for CCDC150 Gene

This gene was present in the common ancestor of chordates.

Orthologs for CCDC150 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia CCDC150 34 33
  • 99.3 (n)
(Canis familiaris)
Mammalia CCDC150 34 33
  • 88.39 (n)
(Mus musculus)
Mammalia Ccdc150 16 34 33
  • 82.2 (n)
(Rattus norvegicus)
Mammalia Ccdc150 33
  • 82.01 (n)
(Bos Taurus)
Mammalia CCDC150 34 33
  • 81.93 (n)
(Monodelphis domestica)
Mammalia CCDC150 34
  • 59 (a)
(Ornithorhynchus anatinus)
Mammalia CCDC150 34
  • 42 (a)
(Anolis carolinensis)
Reptilia CCDC150 34
  • 50 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia ccdc150 33
  • 53.61 (n)
(Danio rerio)
Actinopterygii LOC100534986 33
  • 50 (n)
CCDC150 34
  • 23 (a)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.1101 34
  • 28 (a)
Species where no ortholog for CCDC150 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CCDC150 Gene

Gene Tree for CCDC150 (if available)
Gene Tree for CCDC150 (if available)
Evolutionary constrained regions (ECRs) for CCDC150: view image

Paralogs for CCDC150 Gene Pseudogenes for CCDC150 Gene

genes like me logo Genes that share paralogs with CCDC150: view

No data available for Paralogs for CCDC150 Gene

Variants for CCDC150 Gene

Sequence variations from dbSNP and Humsavar for CCDC150 Gene

SNP ID Clin Chr 02 pos Variation AA Info Type
rs1000020127 -- 196,693,615(+) C/T genic_upstream_transcript_variant, intron_variant
rs1000057212 -- 196,648,633(+) T/C genic_upstream_transcript_variant, intron_variant
rs1000082844 -- 196,669,148(+) A/G genic_upstream_transcript_variant, intron_variant
rs1000119123 -- 196,664,430(+) A/G genic_upstream_transcript_variant, intron_variant
rs1000148976 -- 196,688,360(+) A/G genic_upstream_transcript_variant, intron_variant

Structural Variations from Database of Genomic Variants (DGV) for CCDC150 Gene

Variant ID Type Subtype PubMed ID
esv1075947 CNV insertion 17803354
esv3575323 CNV gain 25503493
esv3593891 CNV gain 21293372
esv992569 CNV insertion 20482838
nsv3096 CNV insertion 18451855
nsv997576 CNV gain 25217958
nsv999398 CNV gain 25217958

Variation tolerance for CCDC150 Gene

Residual Variation Intolerance Score: 92.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 8.17; 84.76% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for CCDC150 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CCDC150 Gene

Disorders for CCDC150 Gene

Additional Disease Information for CCDC150

No disorders were found for CCDC150 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CCDC150 Gene

Publications for CCDC150 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
  2. An organelle-specific protein landscape identifies novel diseases and molecular mechanisms. (PMID: 27173435) Boldt K … UK10K Rare Diseases Group (Nature communications 2016) 3 58
  3. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T … Vidal M (Cell 2014) 3 58
  4. The full-ORF clone resource of the German cDNA Consortium. (PMID: 17974005) Bechtel S … Schupp I (BMC genomics 2007) 4 58
  5. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PMID: 15815621) Hillier LW … Wilson RK (Nature 2005) 4 58

Products for CCDC150 Gene

Sources for CCDC150 Gene

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