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Aliases for CCDC102A Gene

Aliases for CCDC102A Gene

  • Coiled-Coil Domain Containing 102A 2 3 5
  • Coiled-Coil Domain-Containing Protein 102A 3 4

External Ids for CCDC102A Gene

Previous GeneCards Identifiers for CCDC102A Gene

  • GC16M056104
  • GC16M043413

Summaries for CCDC102A Gene

GeneCards Summary for CCDC102A Gene

CCDC102A (Coiled-Coil Domain Containing 102A) is a Protein Coding gene. An important paralog of this gene is CCDC102B.

Additional gene information for CCDC102A Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCDC102A Gene

Genomics for CCDC102A Gene

GeneHancer (GH) Regulatory Elements for CCDC102A Gene

Promoters and enhancers for CCDC102A Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH16J057531 Promoter/Enhancer 2.4 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 615.1 +1.3 1316 8.1 SP1 ZNF652 ZFX ZNF148 NKRF ZNF687 NFIB ZSCAN21 FOS RELA CCDC102A PIR39147 DOK4 ADGRG5
GH16J058391 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 19.4 -855.8 -855771 2.2 SP1 ZFX ELF3 ZKSCAN8 SIX5 ZNF148 NKRF POLR2A MLLT1 ZNF121 ENSG00000276131 GINS3 CNOT1 CCDC102A SNORA50A SETD6 LINC02137 GC16P058413
GH16J057542 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE dbSUPER 14.7 -6.8 -6828 4 SP1 ZNF148 MLLT1 ZNF687 TRIM24 RELA CREM SMARCA4 ZBED1 MTA1 ADGRG5 CCDC102A NUP93 RSPRY1 POLR2C DOK4 GC16P057566
GH16J057626 Promoter/Enhancer 2.5 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 10.3 -92.6 -92578 6.7 ZNF473 CC2D1A ZNF148 MLLT1 ZNF121 GTF2F1 ZSCAN21 CDC5L IKZF1 MCM2 ADGRG1 ENSG00000261633 RSPRY1 ENSG00000260927 POLR2C NUP93 SNORA50A ENSG00000261302 SETD6 ADGRG3
GH16J056930 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 11 +601.6 601611 10.1 MTA3 ZFX SP1 ELF3 ZKSCAN8 MNT CBFA2T2 ZNF148 NKRF POLR2A HERPUD1 RSPRY1 NUP93 NUDT21 POLR2C CETP SLC12A3 ENSG00000261302 ENSG00000261270 CCDC102A
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around CCDC102A on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the CCDC102A gene promoter:
  • AP-1
  • AP-2alphaA
  • AP-2beta
  • AP-2gamma
  • c-Fos
  • c-Jun
  • MIF-1
  • Pax-4a
  • SEF-1 (1)
  • Spz1

Genomic Locations for CCDC102A Gene

Genomic Locations for CCDC102A Gene
chr16:57,512,178-57,537,130
(GRCh38/hg38)
Size:
24,953 bases
Orientation:
Minus strand
chr16:57,546,090-57,570,511
(GRCh37/hg19)
Size:
24,422 bases
Orientation:
Minus strand

Genomic View for CCDC102A Gene

Genes around CCDC102A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CCDC102A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CCDC102A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CCDC102A Gene

Proteins for CCDC102A Gene

  • Protein details for CCDC102A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96A19-C102A_HUMAN
    Recommended name:
    Coiled-coil domain-containing protein 102A
    Protein Accession:
    Q96A19
    Secondary Accessions:
    • Q9BT74

    Protein attributes for CCDC102A Gene

    Size:
    550 amino acids
    Molecular mass:
    62596 Da
    Quaternary structure:
    No Data Available

neXtProt entry for CCDC102A Gene

Post-translational modifications for CCDC102A Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CCDC102A Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for CCDC102A Gene

Domains & Families for CCDC102A Gene

Gene Families for CCDC102A Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for CCDC102A Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for CCDC102A Gene

GenScript: Design optimal peptide antigens:
  • Coiled-coil domain-containing protein 102A (C102A_HUMAN)

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CCDC102A: view

No data available for UniProtKB/Swiss-Prot for CCDC102A Gene

Function for CCDC102A Gene

Phenotypes From GWAS Catalog for CCDC102A Gene

Gene Ontology (GO) - Molecular Function for CCDC102A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003774 motor activity IEA --
genes like me logo Genes that share ontologies with CCDC102A: view
genes like me logo Genes that share phenotypes with CCDC102A: view

Animal Model Products

CRISPR Products

miRNA for CCDC102A Gene

miRTarBase miRNAs that target CCDC102A

Clone Products

  • Applied Biological Materials (abm): Clones for CCDC102A - Now 50% OFF >
  • * CCDC102A as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
  • * CCDC102A tags and reporters available: His, HA, Myc, Flag, GFP, RFP, Luciferase - Browse All

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for CCDC102A Gene

Localization for CCDC102A Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for CCDC102A gene
Compartment Confidence
nucleus 3
cytoskeleton 2
mitochondrion 1
cytosol 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Nuclear bodies (2)
  • Nucleoplasm (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for CCDC102A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016459 myosin complex IEA --
genes like me logo Genes that share ontologies with CCDC102A: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for CCDC102A Gene

Pathways & Interactions for CCDC102A Gene

PathCards logo

SuperPathways for CCDC102A Gene

No Data Available

Gene Ontology (GO) - Biological Process for CCDC102A Gene

None

No data available for Pathways by source and SIGNOR curated interactions for CCDC102A Gene

Drugs & Compounds for CCDC102A Gene

No Compound Related Data Available

Transcripts for CCDC102A Gene

mRNA/cDNA for CCDC102A Gene

(1) REFSEQ mRNAs :
(4) Additional mRNA sequences :
(44) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Unigene Clusters for CCDC102A Gene

Coiled-coil domain containing 102A:
Representative Sequences:

CRISPR Products

Clone Products

  • Applied Biological Materials (abm): Clones for CCDC102A - Now 50% OFF >
  • * CCDC102A as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
  • * CCDC102A tags and reporters available: His, HA, Myc, Flag, GFP, RFP, Luciferase - Browse All

Alternative Splicing Database (ASD) splice patterns (SP) for CCDC102A Gene

No ASD Table

Relevant External Links for CCDC102A Gene

GeneLoc Exon Structure for
CCDC102A
ECgene alternative splicing isoforms for
CCDC102A

Expression for CCDC102A Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for CCDC102A Gene

Protein differential expression in normal tissues from HIPED for CCDC102A Gene

This gene is overexpressed in Bone marrow mesenchymal stem cell (32.0) and Heart (24.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for CCDC102A Gene



NURSA nuclear receptor signaling pathways regulating expression of CCDC102A Gene:

CCDC102A

SOURCE GeneReport for Unigene cluster for CCDC102A Gene:

Hs.644611

Evidence on tissue expression from TISSUES for CCDC102A Gene

  • Nervous system(4.2)
  • Liver(4.1)
genes like me logo Genes that share expression patterns with CCDC102A: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for CCDC102A Gene

Orthologs for CCDC102A Gene

This gene was present in the common ancestor of animals.

Orthologs for CCDC102A Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia CCDC102A 35
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia CCDC102A 35 34
  • 91.14 (n)
OneToOne
dog
(Canis familiaris)
Mammalia CCDC102A 35 34
  • 88.91 (n)
OneToOne
rat
(Rattus norvegicus)
Mammalia Ccdc102a 34
  • 86.58 (n)
mouse
(Mus musculus)
Mammalia Ccdc102a 17 35 34
  • 86.04 (n)
oppossum
(Monodelphis domestica)
Mammalia CCDC102A 35
  • 64 (a)
OneToOne
chicken
(Gallus gallus)
Aves CCDC102A 35 34
  • 78.27 (n)
OneToOne
lizard
(Anolis carolinensis)
Reptilia CCDC102A 35
  • 88 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia ccdc102a 34
  • 64.16 (n)
zebrafish
(Danio rerio)
Actinopterygii ccdc102a 35 34
  • 68.7 (n)
OneToOne
wufc66e01 34
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP007348 34
  • 56.09 (n)
fruit fly
(Drosophila melanogaster)
Insecta CG31638 35 34
  • 55.36 (n)
OneToOne
Species where no ortholog for CCDC102A was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CCDC102A Gene

ENSEMBL:
Gene Tree for CCDC102A (if available)
TreeFam:
Gene Tree for CCDC102A (if available)
Aminode:
Evolutionary constrained regions (ECRs) for CCDC102A: view image

Paralogs for CCDC102A Gene

(2) SIMAP similar genes for CCDC102A Gene using alignment to 2 proteins:

  • C102A_HUMAN
  • L0R6E4_HUMAN
genes like me logo Genes that share paralogs with CCDC102A: view

Variants for CCDC102A Gene

Sequence variations from dbSNP and Humsavar for CCDC102A Gene

SNP ID Clin Chr 16 pos Variation AA Info Type
rs1000067157 -- 57,514,265(-) C/T intron_variant
rs1000413130 -- 57,517,312(-) G/A intron_variant
rs1000418529 -- 57,513,993(-) T/C intron_variant
rs1000512748 -- 57,523,467(-) A/G intron_variant
rs1000566574 -- 57,523,145(-) G/T intron_variant

Structural Variations from Database of Genomic Variants (DGV) for CCDC102A Gene

Variant ID Type Subtype PubMed ID
esv28778 CNV loss 19812545
nsv1055537 CNV loss 25217958
nsv572723 CNV loss 21841781
nsv833245 CNV loss 17160897
nsv952683 CNV deletion 24416366

Variation tolerance for CCDC102A Gene

Residual Variation Intolerance Score: 41.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.57; 30.31% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for CCDC102A Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
CCDC102A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CCDC102A Gene

Disorders for CCDC102A Gene

Additional Disease Information for CCDC102A

No disorders were found for CCDC102A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CCDC102A Gene

Publications for CCDC102A Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 2 3 58
  3. Genome-wide CRISPR-Cas9 Screen Identifies Leukemia-Specific Dependence on a Pre-mRNA Metabolic Pathway Regulated by DCPS. (PMID: 29478914) Yamauchi T … Maeda T (Cancer cell 2018) 3 58
  4. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 58
  5. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin EL … Gygi SP (Cell 2015) 3 58

Products for CCDC102A Gene

  • Biorbyt antibodies for CCDC102A

Sources for CCDC102A Gene

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