Aliases for CBX7 Gene
External Ids for CBX7 Gene
- HGNC: 1557
- Entrez Gene: 23492
- Ensembl: ENSG00000100307
- OMIM: 608457
- UniProtKB: O95931
Previous GeneCards Identifiers for CBX7 Gene
- GC22U990068
- GC22M036145
- GC22M037769
- GC22M037851
- GC22M039518
- GC22M039519
- GC22M022493
- GC22M039605
- GC22M040104
- GC22M039153
- GC22M039830
- GC22M039833
- GC22M039940
- GC22M040628
- GC22M041076
- GC22M041474
Summaries for CBX7 Gene
-
This gene encodes a protein that contains the CHROMO (CHRomatin Organization MOdifier) domain. The encoded protein is a component of the Polycomb repressive complex 1 (PRC1), and is thought to control the lifespan of several normal human cells. [provided by RefSeq, Oct 2016]
GeneCards Summary for CBX7 Gene
CBX7 (Chromobox 7) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include chromatin binding and single-stranded RNA binding. An important paralog of this gene is CBX8.
UniProtKB/Swiss-Prot for CBX7 Gene
-
Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A Lys-119, rendering chromatin heritably changed in its expressibility. Promotes histone H3 trimethylation at Lys-9 (H3K9me3). Binds to trimethylated lysine residues in histones, and possibly also other proteins. Regulator of cellular lifespan by maintaining the repression of CDKN2A, but not by inducing telomerase activity.
Additional gene information for CBX7 Gene
- Monarch Initiative
- Search for CBX7 at DataMed
- Search for CBX7 at HumanCyc
No data available for CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CBX7 Gene
Genomics for CBX7 Gene
GeneHancer (GH) Regulatory Elements for CBX7 Gene
Promoters and enhancers for CBX7 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around CBX7 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Locations for CBX7 Gene
Genomic Locations for CBX7 Gene
- chr22:39,120,167-39,152,674
- (GRCh38/hg38)
- Size:
- 32,508 bases
- Orientation:
- Minus strand
- chr22:39,516,172-39,548,679
- (GRCh37/hg19)
Genomic View for CBX7 Gene
Genes around CBX7 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 22q13.1 by Ensembl
- 22q13.1 by Entrez Gene
- 22q13.1 by HGNC
CBX7 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for CBX7 Gene
Proteins for CBX7 Gene
-
Protein details for CBX7 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- O95931-CBX7_HUMAN
- Recommended name:
- Chromobox protein homolog 7
- Protein Accession:
- O95931
- Q86T17
Protein attributes for CBX7 Gene
- Size:
- 251 amino acids
- Molecular mass:
- 28341 Da
- Quaternary structure:
-
- Component of a PRC1-like complex. Interacts with RING1 and RNF2/RING1B, but not with BMI1, EED or EZH2. Interacts with PCGF1, PCGF2, PCGF3, PCGF5 and PCGF6.
- Miscellaneous:
-
- The human orthologuous proteins of Drosphila Polycomb group protein Pc, CBX2, CBX4, CBX6, CBX7 and CBX8, show distinct nuclear localizations, contribute differently to transcriptional repression, and appear to be part of distinct PRC1-like protein complexes.
Protein Expression for CBX7 Gene
Post-translational modifications for CBX7 Gene
Other Protein References for CBX7 Gene
Antibody Products
- Novus Biologicals Antibodies for CBX7
-
Abcam antibodies for CBX7
- Invitrogen Antibodies for CBX7
- GeneTex CBX7 antibody for CBX7
-
Santa Cruz Biotechnology (SCBT) Antibodies for CBX7
Protein Products
-
OriGene Purified Proteins for CBX7
- Search Origene for MassSpec and Protein Over-expression Lysates for CBX7
- Origene Custom Protein Services for CBX7
- antibodies-online: Search results for 12 available CBX7 Proteins ranked by validation data
- Compare Top CBX7 Proteins
-
Quality Products:
- Search GeneTex for Proteins for CBX7
-
Abcam proteins for CBX7
Assay Products
- antibodies-online: Search results for available CBX7 related products ranked by validation data
No data available for DME Specific Peptides for CBX7 Gene
Domains & Families for CBX7 Gene
Gene Families for CBX7 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Protein Domains for CBX7 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for CBX7 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
No data available for UniProtKB/Swiss-Prot for CBX7 Gene
Function for CBX7 Gene
Molecular function for CBX7 Gene
- GENATLAS Biochemistry:
- Drosophila polycomb-like (PcG) chromobox homolog 7,mouse ortholog,involved in the compaction of chromatin
- UniProtKB/Swiss-Prot Function:
- Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A Lys-119, rendering chromatin heritably changed in its expressibility. Promotes histone H3 trimethylation at Lys-9 (H3K9me3). Binds to trimethylated lysine residues in histones, and possibly also other proteins. Regulator of cellular lifespan by maintaining the repression of CDKN2A, but not by inducing telomerase activity.
Phenotypes From GWAS Catalog for CBX7 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005515 | protein binding | IPI | 10369680 |
Phenotypes for CBX7 Gene
- MGI mutant phenotypes for CBX7:
- inferred from 2 alleles
- GenomeRNAi human phenotypes for CBX7:
-
- Increased viability
- Increased gamma-H2AX phosphorylation
- Decreased viability in esophageal squamous lineage
- Decreased shRNA abundance (Z-score < -2)
- Dynamic nuclei (hole, folded or small irregular)
- Increased shRNA abundance (Z-score > 2)
- Effect on mitosis
- Negative genetic interaction between PTTG1-/- and PTTG1+/+
- Decreased homologous recombination repair frequency
- Downregulation of Wnt pathway after Wnt3A stimulation
- Increased Sindbis virus (SINV) infection
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for CBX7
-
-
ViGene Biosciences lentiviral particle packaged cDNA for CBX7 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for CBX7 gene
- Search ViGene Biosciences for CBX7
CRISPR Products
-
OriGene CRISPR knockouts for CBX7
- genomics-online: gRNA clones - Search results for 86 available CBX7 gene related products
- Overview of 86 available CBX7 gene related products
- Applied Biological Materials CRISPR for CBX7
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for CBX7
- GenScript: Design CRISPR guide RNA sequences for CBX7
miRNA for CBX7 Gene
- miRTarBase miRNAs that target CBX7
-
- hsa-mir-421 (MIRT001104)
- hsa-mir-181b-5p (MIRT006371)
- hsa-mir-766-3p (MIRT039038)
- hsa-mir-6818-3p (MIRT485703)
- hsa-mir-4515 (MIRT485704)
- hsa-mir-6077 (MIRT485705)
- hsa-mir-7-5p (MIRT485706)
- hsa-mir-3169 (MIRT485707)
- hsa-mir-4700-3p (MIRT485708)
- hsa-mir-548ay-3p (MIRT532655)
- hsa-mir-548at-3p (MIRT532656)
- hsa-mir-548as-3p (MIRT532657)
- hsa-mir-548t-3p (MIRT532658)
- hsa-mir-548ap-3p (MIRT532659)
- hsa-mir-548aa (MIRT532660)
- hsa-mir-19b-3p (MIRT728040)
- hsa-mir-19a-3p (MIRT728042)
- hsa-mir-18a-3p (MIRT731983)
- hsa-mir-9-5p (MIRT733471)
- hsa-mir-9-3p (MIRT734803)
miRNA Products
- Search ViGene Biosciences for CBX7
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for CBX7
- Browse OriGene Inhibitory RNA Products For CBX7
- genomics-online: shRNA clones - Search results for 86 available CBX7 gene related products
- Overview of 86 available CBX7 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for CBX7 gene
Clone Products
- VectorBuilder custom plasmid, inducible vectors for CBX7
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CBX7
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Addgene plasmids for CBX7
- Applied Biological Materials Clones for CBX7
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for CBX7
-
ViGene Biosciences adenoviral particle packaged cDNA for CBX7 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for CBX7 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for CBX7 gene
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for CBX7 Gene
Localization for CBX7 Gene
Subcellular locations from UniProtKB/Swiss-Prot for CBX7 Gene
- Nucleus.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| cytosol | 5 |
- Cytosol (3)
- Nucleoplasm (3)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000790 | nuclear chromatin | IDA | 19636380 |
| GO:0005634 | nucleus | IEA,IDA | 21282530 |
| GO:0005654 | nucleoplasm | IDA | -- |
| GO:0005829 | cytosol | IDA | -- |
| GO:0031519 | PcG protein complex | IDA | 21282530 |
Pathways & Interactions for CBX7 Gene
No Data Available
Interacting Proteins for CBX7 Gene
Selected Interacting proteins:
O95931-CBX7_HUMAN
ENSP00000216133
for CBX7 Gene via
MINT
STRING
IID
UniProtKB
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000122 | negative regulation of transcription by RNA polymerase II | IMP | 19636380 |
| GO:0006351 | transcription, DNA-templated | IEA | -- |
| GO:0006355 | regulation of transcription, DNA-templated | IEA | -- |
| GO:0016569 | covalent chromatin modification | IEA | -- |
No data available for Pathways by source and SIGNOR curated interactions for CBX7 Gene
Drugs & Compounds for CBX7 Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| UNC3866 | Pharma | a potent antagonist of CBX4 and CBX7 chromodomains | 0 |
(1) ApexBio Compounds for CBX7 Gene
| Compound | Action | Cas Number |
|---|---|---|
| UNC3866 | a potent antagonist of CBX4 and CBX7 chromodomains |
Transcripts for CBX7 Gene
mRNA/cDNA for CBX7 Gene
- (11) REFSEQ mRNAs :
- (5) Additional mRNA sequences :
- (207) Selected AceView cDNA sequences:
- (7) Ensembl transcripts including schematic representations, and UCSC links where relevant :
CRISPR Products
-
OriGene CRISPR knockouts for CBX7
- genomics-online: gRNA clones - Search results for 86 available CBX7 gene related products
- Overview of 86 available CBX7 gene related products
- Applied Biological Materials CRISPR for CBX7
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for CBX7
- GenScript: Design CRISPR guide RNA sequences for CBX7
miRNA Products
- Search ViGene Biosciences for CBX7
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for CBX7
- Browse OriGene Inhibitory RNA Products For CBX7
- genomics-online: shRNA clones - Search results for 86 available CBX7 gene related products
- Overview of 86 available CBX7 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for CBX7 gene
Clone Products
- VectorBuilder custom plasmid, inducible vectors for CBX7
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CBX7
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Addgene plasmids for CBX7
- Applied Biological Materials Clones for CBX7
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
| ExUns: | 1 | ^ | 2a | · | 2b | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | ^ | 6a | · | 6b |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | |||||||||||||||
| SP2: | |||||||||||||||||
| SP3: |
Expression for CBX7 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Brain (Nervous System)
- Adult Endothelial Cells Blood Brain Barrier
-
Endothelium (Cardiovascular System)
- Adult Endothelial Cells Blood Brain Barrier
This gene is overexpressed in Retina (25.5) and Blymphocyte (21.7).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for CBX7 Gene
NURSA nuclear receptor signaling pathways regulating expression of CBX7 Gene:
CBX7SOURCE GeneReport for Unigene cluster for CBX7 Gene:
Hs.356416Evidence on tissue expression from TISSUES for CBX7 Gene
- Nervous system(4.7)
- Eye(2.4)
- Thyroid gland(2)
Primer Products
-
OriGene qPCR primer pairs for CBX7
Gene Expression Assay Products
No data available for mRNA differential expression in normal tissues , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for CBX7 Gene
Orthologs for CBX7 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | CBX7 33 34 |
|
||
| cow (Bos Taurus) |
Mammalia | CBX7 33 34 |
|
||
| dog (Canis familiaris) |
Mammalia | CBX7 33 34 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Cbx7 33 |
|
||
| mouse (Mus musculus) |
Mammalia | Cbx7 33 16 34 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | CBX7 34 |
|
OneToOne | |
| oppossum (Monodelphis domestica) |
Mammalia | CBX7 34 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | CBX7 33 34 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | CBX7 34 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | cbx7 33 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | LOC101882803 33 |
|
||
| cbx7b 34 |
|
OneToMany | |||
| cbx7a 34 |
|
OneToMany | |||
| fruit fly (Drosophila melanogaster) |
Insecta | Pc 34 |
|
OneToMany |
- Species where no ortholog for CBX7 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for CBX7 Gene
Variants for CBX7 Gene
| SNP ID | Clin | Chr 22 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs193920857 | uncertain-significance, Malignant tumor of prostate | 39,138,655(-) | G/C | coding_sequence_variant, missense_variant | |
| rs1000032566 | -- | 39,139,062(-) | A/G | intron_variant | |
| rs1000077771 | -- | 39,146,085(-) | G/A | intron_variant | |
| rs1000295982 | -- | 39,140,252(-) | C/T | intron_variant | |
| rs1000358300 | -- | 39,135,452(-) | A/C | intron_variant |
Residual Variation Intolerance Score:
43% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.41;
8.97% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for CBX7 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- CBX7
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CBX7 Gene
Disorders for CBX7 Gene
Additional Disease Information for CBX7
No disorders were found for CBX7 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CBX7 Gene
Publications for CBX7 Gene
- Several distinct polycomb complexes regulate and co-localize on the INK4a tumor suppressor locus. (PMID: 19636380) Maertens GN … Peters G (PloS one 2009) 3 4 22 58
- Recognition and specificity determinants of the human cbx chromodomains. (PMID: 21047797) Kaustov L … Arrowsmith CH (The Journal of biological chemistry 2011) 3 4 58
- Interaction proteomics analysis of polycomb proteins defines distinct PRC1 complexes in mammalian cells. (PMID: 21282530) Vandamme J … Angrand PO (Molecular & cellular proteomics : MCP 2011) 3 4 58
- Polycomb group targeting through different binding partners of RING1B C-terminal domain. (PMID: 20696397) Wang R … Kim CA (Structure (London, England : 1993) 2010) 3 4 58
- Polycomb CBX7 directly controls trimethylation of histone H3 at lysine 9 at the p16 locus. (PMID: 21060834) Li Q … Deng D (PloS one 2010) 3 4 58
Products for CBX7 Gene
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- ApexBio compounds for CBX7
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- VectorBuilder custom plasmid, inducible vectors for CBX7
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CBX7
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Addgene plasmids for CBX7
- antibodies-online: Search results for 23 available CBX7 Antibodies ranked by validation data
- Compare Top CBX7 Antibodies
- antibodies-online: Search results for available CBX7 related products ranked by validation data
- antibodies-online: Search results for 12 available CBX7 Proteins ranked by validation data
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- Quality Products:
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- Search ViGene Biosciences for CBX7
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- Search Santa Cruz Biotechnology (SCBT) for CBX7 siRNA/shRNA
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- Horizon Cell Lines for CBX7
- genomics-online: cdna clones - Search results for 86 available CBX7 gene related products
- Overview of 86 available CBX7 gene related products
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- Overview of 86 available CBX7 gene related products
- genomics-online: gRNA clones - Search results for 86 available CBX7 gene related products
- Overview of 86 available CBX7 gene related products
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- Overview of 86 available CBX7 gene related products
- genomics-online: shRNA clones - Search results for 86 available CBX7 gene related products
- Overview of 86 available CBX7 gene related products
Sources for CBX7 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew
- (158) Applied Biosystems
