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Aliases for CBR4 Gene
Aliases for CBR4 Gene
External Ids for CBR4 Gene
- HGNC: 25891
- Entrez Gene: 84869
- Ensembl: ENSG00000145439
- UniProtKB: Q8N4T8
Previous GeneCards Identifiers for CBR4 Gene
- GC04M170283
- GC04M170145
- GC04M169815
- GC04M165662
Summaries for CBR4 Gene
GeneCards Summary for CBR4 Gene
CBR4 (Carbonyl Reductase 4) is a Protein Coding gene. Diseases associated with CBR4 include Pancreatic Cancer 1 and Myopathy, Centronuclear, 6, With Fiber-Type Disproportion. Among its related pathways are Fatty acid biosynthesis (KEGG) and Metabolism. Gene Ontology (GO) annotations related to this gene include oxidoreductase activity and NADPH binding.
UniProtKB/Swiss-Prot Summary for CBR4 Gene
-
The heterotetramer with HSD17B8 has NADH-dependent 3-ketoacyl-acyl carrier protein reductase activity, and thereby plays a role in mitochondrial fatty acid biosynthesis (PubMed:19571038, PubMed:25203508). Within the heterotetramer, HSD17B8 binds NADH; CBR4 binds NADPD (PubMed:25203508). The homotetramer has NADPH-dependent quinone reductase activity (PubMed:19000905). Both homotetramer and the heterotetramer have broad substrate specificity and can reduce 9,10-phenanthrenequinone, 1,4-benzoquinone and various other o-quinones and p-quinones (in vitro) (PubMed:19000905, PubMed:19571038, PubMed:25203508).
Additional gene information for CBR4 Gene
- HGNC(25891)
- Entrez Gene(84869)
- Ensembl(ENSG00000145439)
- UniProtKB(Q8N4T8)
- Open Targets Platform(ENSG00000145439)
- Search for CBR4 at DataMed
- Search for CBR4 at HumanCyc
No data available for Entrez Gene Summary , CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for CBR4 Gene
Genomics for CBR4 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for CBR4 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around CBR4 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for CBR4
- Top Transcription factor binding sites by QIAGEN in the CBR4 gene promoter:
-
- Bach2
- FOXJ2
- HFH-1
- HNF-1
- HNF-1A
- Pax-2
- Pax-2a
- Pax-2b
- POU3F1
- TBP
Genomic Locations for CBR4 Gene
Genomic Locations for CBR4 Gene
- chr4:168,863,770-169,010,284
- (GRCh38/hg38)
- Size:
- 146,515 bases
- Orientation:
- Minus strand
- chr4:169,784,921-169,931,468
- (GRCh37/hg19)
- Size:
- 146,548 bases
- Orientation:
- Minus strand
Genomic View for CBR4 Gene
Genes around CBR4 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 4q32.3 by HGNC
- 4q32.3 by Entrez Gene
- 4q32.3 by Ensembl
CBR4 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for CBR4 Gene
Proteins for CBR4 Gene
-
Protein details for CBR4 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q8N4T8-CBR4_HUMAN
- Recommended name:
- Carbonyl reductase family member 4
- Protein Accession:
- Q8N4T8
- Q8WTW8
- Q96K93
Protein attributes for CBR4 Gene
- Size:
- 237 amino acids
- Molecular mass:
- 25301 Da
- Quaternary structure:
-
- Homotetramer (in vitro) (PubMed:19000905). Heterotetramer with HSD17B8; contains two molecules each of HSD17B8 and CBR4 (PubMed:19571038, PubMed:25203508). Does not form homotetramers when HSD17B8 is coexpressed, only heterotetramers (in vitro) (PubMed:25203508).
Protein Expression for CBR4 Gene
Selected DME Specific Peptides for CBR4 Gene
- Q8N4T8:
-
- GSIVNVGS
- FLVNAAGINRD
- TGHVLVVDGGLQL
- VNVVAPGF
- GGSRGIG
Post-translational modifications for CBR4 Gene
Other Protein References for CBR4 Gene
Antibody Products
- Creative Diagnostics Anti-CBR4 monoclonal antibody
- Novus Biologicals Antibodies for CBR4
- Invitrogen Antibodies for CBR4 (AFLGC-CBR4)
-
Boster Bio Antibodies for CBR4
Protein Products
- Creative Biomart Recombinant Human CBR4, His-tagged
- Search Origene for MassSpec and Protein Over-expression Lysates for CBR4
- Origene Custom Protein Services for CBR4
- ProSpec Recombinant Proteins for CBR4
-
Abcam proteins for CBR4
Domains & Families for CBR4 Gene
Gene Families for CBR4 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Protein Domains for CBR4 Gene
- InterPro:
- Blocks:
-
- Short-chain dehydrogenase/reductase SDR
- Glucose/ribitol dehydrogenase family signature
- ProtoNet:
Suggested Antigen Peptide Sequences for CBR4 Gene
- GenScript: Design optimal peptide antigens:
-
- Quinone reductase CBR4 (CBR4_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q8N4T8UniProtKB/Swiss-Prot:
CBR4_HUMAN :- Belongs to the short-chain dehydrogenases/reductases (SDR) family.
- Family:
-
- Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Function for CBR4 Gene
Molecular function for CBR4 Gene
- UniProtKB/Swiss-Prot Function:
- The heterotetramer with HSD17B8 has NADH-dependent 3-ketoacyl-acyl carrier protein reductase activity, and thereby plays a role in mitochondrial fatty acid biosynthesis (PubMed:19571038, PubMed:25203508). Within the heterotetramer, HSD17B8 binds NADH; CBR4 binds NADPD (PubMed:25203508). The homotetramer has NADPH-dependent quinone reductase activity (PubMed:19000905). Both homotetramer and the heterotetramer have broad substrate specificity and can reduce 9,10-phenanthrenequinone, 1,4-benzoquinone and various other o-quinones and p-quinones (in vitro) (PubMed:19000905, PubMed:19571038, PubMed:25203508).
- UniProtKB/Swiss-Prot BiophysicochemicalProperties:
- Kinetic parameters: KM=11 uM for NADPH (for homotetramer) {ECO:0000269|PubMed:19000905}; KM=1.6 uM for 9,10-phenanthrenequinone (for homotetramer) {ECO:0000269|PubMed:19000905}; KM=1.9 uM for 1,4-benzoquinone (for homotetramer) {ECO:0000269|PubMed:19000905}; pH dependence: Optimum pH is 6-8 (for homotetramer). {ECO:0000269|PubMed:19000905};
Enzyme Numbers (IUBMB) for CBR4 Gene
Phenotypes From GWAS Catalog for CBR4 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003955 | NAD(P)H dehydrogenase (quinone) activity | IDA | 20837989 |
| GO:0005515 | protein binding | IPI | 19571038 |
| GO:0008753 | NADPH dehydrogenase (quinone) activity | IDA | 19000905 |
| GO:0016491 | oxidoreductase activity | IEA | -- |
| GO:0016616 | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | IBA | 21873635 |
Phenotypes for CBR4 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for CBR4 - Select products 50% OFF >
- * CBR4 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for CBR4
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for CBR4
-
Santa Cruz Biotechnology (SCBT) CRISPR for CBR4
miRNA for CBR4 Gene
- miRTarBase miRNAs that target CBR4
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for CBR4
- Browse OriGene Inhibitory RNA Products For CBR4
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for CBR4
Clone Products
- Applied Biological Materials (abm): Clones for CBR4 - Select products 50% OFF >
- * CBR4 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for CBR4
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for CBR4
Cell Line Products
-
Horizon Cell Lines for CBR4
No data available for Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for CBR4 Gene
Localization for CBR4 Gene
Subcellular locations from UniProtKB/Swiss-Prot for CBR4 Gene
- Mitochondrion matrix.
| Compartment | Confidence |
|---|---|
| mitochondrion | 5 |
| cytosol | 3 |
| plasma membrane | 2 |
| nucleus | 2 |
| extracellular | 1 |
| cytoskeleton | 1 |
| endoplasmic reticulum | 1 |
| endosome | 1 |
| golgi apparatus | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005739 | mitochondrion | IEA | -- |
| GO:0005759 | mitochondrial matrix | TAS | -- |
| GO:1990204 | oxidoreductase complex | IMP | 25203508 |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for CBR4 Gene
Pathways & Interactions for CBR4 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Metabolism |
.40
|
|
| 2 | Fatty acid biosynthesis (KEGG) | ||
| 3 | Fatty Acyl-CoA Biosynthesis | ||
| 4 | Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) | ||
Pathways by source for CBR4 Gene
3 Reactome pathways for CBR4 Gene
3 KEGG pathways for CBR4 Gene
UniProtKB/Swiss-Prot Q8N4T8-CBR4_HUMAN
- Pathway: Lipid metabolism; fatty acid biosynthesis.
Interacting Proteins for CBR4 Gene
Selected Interacting proteins:
Q8N4T8-CBR4_HUMAN
ENSP00000303525
for CBR4 Gene via
UniProtKB
STRING
IID
GPS-Prot Interaction Network for CBR4
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006629 | lipid metabolic process | IEA | -- |
| GO:0006631 | fatty acid metabolic process | IEA | -- |
| GO:0006633 | fatty acid biosynthetic process | IBA,IMP | 25203508 |
| GO:0044597 | daunorubicin metabolic process | IMP | 20837989 |
| GO:0044598 | doxorubicin metabolic process | IMP | 20837989 |
No data available for SIGNOR curated interactions for CBR4 Gene
Drugs & Compounds for CBR4 Gene
No Compound Related Data Available
Drug Products
- Creative Biomart Recombinant Human CBR4, His-tagged
Transcripts for CBR4 Gene
mRNA/cDNA for CBR4 Gene
- 1 REFSEQ mRNAs :
- 11 NCBI additional mRNA sequence :
- 7 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000510042 1198 nts (view in UCSC)
- ENST00000509108 546 nts (view in UCSC)
- ENST00000306193 3440 nts (view in UCSC)
- ENST00000504480 1602 nts (view in UCSC)
- ENST00000504561 1052 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for CBR4 - Select products 50% OFF >
- * CBR4 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for CBR4
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for CBR4
-
Santa Cruz Biotechnology (SCBT) CRISPR for CBR4
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for CBR4
- Browse OriGene Inhibitory RNA Products For CBR4
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for CBR4
Clone Products
- Applied Biological Materials (abm): Clones for CBR4 - Select products 50% OFF >
- * CBR4 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for CBR4
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for CBR4
| ExUns: | 1a | · | 1b | ^ | 2a | · | 2b | ^ | 3a | · | 3b | ^ | 4a | · | 4b | ^ | 5 | ^ | 6a | · | 6b | · | 6c | ^ | 7a | · | 7b | ^ | 8a | · | 8b |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | |||||||||||||||||||||||||||
| SP2: | - | - | - | - | - | - | |||||||||||||||||||||||||
| SP3: | - | - | |||||||||||||||||||||||||||||
| SP4: | - | ||||||||||||||||||||||||||||||
| SP5: | - | - | - | ||||||||||||||||||||||||||||
| SP6: | - | - | |||||||||||||||||||||||||||||
| SP7: | |||||||||||||||||||||||||||||||
| SP8: | - | - | - | - | - |
Relevant External Links for CBR4 Gene
- GeneLoc Exon Structure for
- CBR4
Expression for CBR4 Gene
This gene is overexpressed in Liver (6.6).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for CBR4 Gene
- Elite partner
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for CBR4
SOURCE GeneReport for Unigene cluster for CBR4 Gene:
Hs.659311mRNA Expression by UniProt/SwissProt for CBR4 Gene:
Q8N4T8-CBR4_HUMAN
Tissue specificity:
Detected in liver and kidney (at protein level).
Evidence on tissue expression from TISSUES for CBR4 Gene
- Liver(4.4)
- Intestine(4.3)
- Nervous system(3.6)
- Skin(2.3)
Primer Products
-
OriGene qPCR primer pairs for CBR4
-
OriGene qPCR primer pairs and template standards for CBR4
Gene Expression Assay Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for CBR4 Gene
Orthologs for CBR4 Gene
This gene was present in the common ancestor of eukaryotes.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | CBR4 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | CBR4 31 |
|
OneToOne | |
| LOC477352 30 |
|
||||
| Platypus (Ornithorhynchus anatinus) |
Mammalia | CBR4 31 |
|
OneToOne | |
| Mouse (Mus musculus) |
Mammalia | Cbr4 30 17 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | CBR4 30 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Cbr4 30 |
|
||
| Oppossum (Monodelphis domestica) |
Mammalia | CBR4 31 |
|
OneToOne | |
| Chicken (Gallus gallus) |
Aves | CBR4 30 31 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | CBR4 31 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | cbr4 30 |
|
||
| Str.15559 30 |
|
||||
| African clawed frog (Xenopus laevis) |
Amphibia | Xl.11545 30 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | cbr4 30 31 |
|
OneToOne | |
| Thale Cress (Arabidopsis thaliana) |
eudicotyledons | AT1G24360 30 |
|
||
| Rice (Oryza sativa) |
Liliopsida | Os12g0242700 30 |
|
||
| Bread mold (Neurospora crassa) |
Ascomycetes | NCU03525 30 |
|
||
| Fission Yeast (Schizosaccharomyces pombe) |
Schizosaccharomycetes | oar2 30 |
|
- Species where no ortholog for CBR4 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
Evolution for CBR4 Gene
- ENSEMBL:
- Gene Tree for CBR4 (if available)
- TreeFam:
- Gene Tree for CBR4 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for CBR4: view image
Paralogs for CBR4 Gene
(9) SIMAP similar genes for CBR4 Gene using alignment to 5 proteins:
- CBR4_HUMAN
- D6RAV8_HUMAN
- D6RGF2_HUMAN
- D6RJF4_HUMAN
- H0Y962_HUMAN
No data available for Paralogs for CBR4 Gene
Variants for CBR4 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for CBR4 Gene
| SNP ID | Clinical significance and condition | Chr 04 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| 641520 | Uncertain Significance: Pancreatic adenocarcinoma | 168,924,286(-) | T/G | MISSENSE_VARIANT | |
| 648376 | Uncertain Significance: Pancreatic adenocarcinoma | 168,921,627(-) | G/A | MISSENSE_VARIANT | |
| 650493 | Uncertain Significance: Pancreatic adenocarcinoma | 168,913,931(-) | G/A | MISSENSE_VARIANT | |
| 654773 | Uncertain Significance: Pancreatic adenocarcinoma | 168,898,493(-) | G/A | MISSENSE_VARIANT | |
| 658471 | Uncertain Significance: Pancreatic adenocarcinoma | 168,924,949(-) | C/T | MISSENSE_VARIANT |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv34043 | CNV | loss | 18971310 |
| nsv1026854 | CNV | gain | 25217958 |
Residual Variation Intolerance Score:
41.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
1.66;
31.76% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for CBR4 Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CBR4 Gene
Disorders for CBR4 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| pancreatic cancer 1 |
|
|
| myopathy, centronuclear, 6, with fiber-type disproportion |
|
|
| myopathy, centronuclear, 1 |
|
|
Search CBR4 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for CBR4
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
No data available for UniProtKB/Swiss-Prot and Genatlas for CBR4 Gene
Publications for CBR4 Gene
- Insights into mitochondrial fatty acid synthesis from the structure of heterotetrameric 3-ketoacyl-ACP reductase/3R-hydroxyacyl-CoA dehydrogenase. (PMID: 25203508) Venkatesan R … Chen Z (Nature communications 2014) 3 4
- Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. (PMID: 20877624) Hendrickson SL … O'Brien SJ (PloS one 2010) 3 41
- 17beta-hydroxysteroid dehydrogenase type 8 and carbonyl reductase type 4 assemble as a ketoacyl reductase of human mitochondrial FAS. (PMID: 19571038) Chen Z … Hiltunen JK (FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2009) 3 4
- The SDR (short-chain dehydrogenase/reductase and related enzymes) nomenclature initiative. (PMID: 19027726) Persson B … Oppermann U (Chemico-biological interactions 2009) 2 3
- Human carbonyl reductase 4 is a mitochondrial NADPH-dependent quinone reductase. (PMID: 19000905) Endo S … Hara A (Biochemical and biophysical research communications 2008) 3 4
ExternalLinks
Products for CBR4 Gene
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for MassSpec and Protein Over-expression Lysates for CBR4
- Origene Custom Protein Services for CBR4
- Origene shrna, sirna, and RNAi products in human, mouse, rat for CBR4
- Browse OriGene Inhibitory RNA Products For CBR4
- OriGene qPCR primer pairs for CBR4
- OriGene qPCR primer pairs and template standards for CBR4
- OriGene CRISPR knockouts for CBR4
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For CBR4
- Sino Biological Human cDNA Clone for CBR4
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse cDNA Clones
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for CBR4
- Novus Biologicals proteins and lysates for CBR4
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Abcam proteins for CBR4
- Find your target
- Browse Primary Antibodies
- Browse Conjugated Primary Antibodies
- Browse Secondary Antibodies
- Browse ELISA Kits
- Browse Matched Antibody Pairs
- Browse Proteins and Peptides
- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
- Browse Recombinant Antibodies
- VectorBuilder Custom and pre-made DNA vectors for CBR4 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for CBR4 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for CBR4 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for CBR4 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for CBR4
- antibodies-online: Show 16 available CBR4 Antibodies ranked by validation data
- Compare Top CBR4 Antibodies
- antibodies-online: Search results for available CBR4 related products ranked by validation data
- antibodies-online: Show 13 available CBR4 Proteins ranked by validation data
- Compare Top CBR4 Proteins
- Horizon Cell Lines for CBR4
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for CBR4
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for CBR4
- Search GeneCopoeia for miRNA 3'UTR Target clone products for CBR4
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for CBR4
- Boster Bio Antibodies for CBR4
- Browse Boster Bio ELISA Kits
Sources for CBR4 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
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