Free for academic non-profit institutions. Other users need a Commercial license
This gene is a member of the cobalamin transport protein family. It encodes a glycoprotein secreted by parietal cells of the gastric mucosa and is required for adequate absorption of vitamin B12. Vitamin B12 is necessary for erythrocyte maturation and mutations in this gene may lead to congenital pernicious anemia. [provided by RefSeq, Jul 2008] See more...
Aliases for CBLIF Gene
Aliases for CBLIF Gene
External Ids for CBLIF Gene
- HGNC: 4268
- NCBI Entrez Gene: 2694
- Ensembl: ENSG00000134812
- OMIM®: 609342
- UniProtKB/Swiss-Prot: P27352
Previous HGNC Symbols for CBLIF Gene
- GIF
Summaries for CBLIF Gene
-
This gene is a member of the cobalamin transport protein family. It encodes a glycoprotein secreted by parietal cells of the gastric mucosa and is required for adequate absorption of vitamin B12. Vitamin B12 is necessary for erythrocyte maturation and mutations in this gene may lead to congenital pernicious anemia. [provided by RefSeq, Jul 2008]
GeneCards Summary for CBLIF Gene
CBLIF (Cobalamin Binding Intrinsic Factor) is a Protein Coding gene. Diseases associated with CBLIF include Intrinsic Factor Deficiency and Congenital Intrinsic Factor Deficiency. Among its related pathways are Gastric acid production and Metabolism of water-soluble vitamins and cofactors. An important paralog of this gene is TCN1.
UniProtKB/Swiss-Prot Summary for CBLIF Gene
-
Promotes absorption of the essential vitamin cobalamin (Cbl) in the ileum. After interaction with CUBN, the CBLIF-cobalamin complex is internalized via receptor-mediated endocytosis.
Additional gene information for CBLIF Gene
No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for CBLIF Gene
Genomics for CBLIF Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for CBLIF Gene
| GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
|---|---|---|---|---|---|---|---|---|---|---|
| GH11J059849 | Enhancer | 0.5 | Ensembl | 250.7 | -1.7 | -1700 | 1.6 | FOXK2 ATF4 CEBPB ATF3 PKNOX1 ZFHX2 | CBLIF STX3 lnc-TCN1-1 TCN1 | |
| GH11J059845 | Promoter | 0.3 | EPDnew | 250.7 | 0.0 | -18 | 0.1 | CBLIF lnc-TCN1-1 TCN1 | ||
| GH11J059846 | Enhancer | 0.2 | ENCODE | 250.7 | -0.2 | -182 | 0.2 | CBLIF lnc-TCN1-1 TCN1 | ||
| GH11J059891 | Enhancer | 0.9 | Ensembl ENCODE | 10.7 | -46.6 | -46575 | 1 | IKZF1 ZNF592 POLR2A NONO YY1 ZNF316 NFE2 PRDM10 ZNF318 EHMT2 | TCN1 CBLIF MS4A2 piR-38351-077 SRD5A3P1 NONHSAG008417.2 OOSP3 OOSP4A | |
| GH11J059918 | Enhancer | 0.8 | Ensembl ENCODE | 11.4 | -73.5 | -73534 | 1 | ZNF654 CTCF REST CEBPB DEK RAD21 RFX5 SMC3 THRAP3 ZNF384 | lnc-OOSP2-3 TCN1 CBLIF OOSP2 MS4A2 SRD5A3P1 OOSP3 OOSP4A |
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around CBLIF on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for CBLIF
Genomic Locations for CBLIF Gene
Latest Assembly
- chr11:59,829,268-59,845,501
- (GRCh38/hg38)
- Size:
- 16,234 bases
- Orientation:
- Minus strand
Previous Assembly
- chr11:59,596,746-59,612,972
- (GRCh37/hg19 by Entrez Gene)
- Size:
- 16,227 bases
- Orientation:
- Minus strand
Genomic View for CBLIF Gene
Genes around CBLIF on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 11q12.1 by HGNC
- 11q12.1 by Entrez Gene
- 11q12.1 by Ensembl
CBLIF Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for CBLIF Gene
Proteins for CBLIF Gene
-
Protein details for CBLIF Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P27352-IF_HUMAN
- Recommended name:
- Cobalamin binding intrinsic factor
- Protein Accession:
- P27352
- B2RAN8
- B4DVZ1
Protein attributes for CBLIF Gene
- Size:
- 417 amino acids
- Molecular mass:
- 45416 Da
- Quaternary structure:
-
- Interacts with CUBN (via CUB domains).
Post-translational modifications for CBLIF Gene
Other Protein References for CBLIF Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibodies for research
-
Custom Antibody ServicesOriGene Antibodies for CBLIF
- Novus Biologicals Antibodies for CBLIF
-
Abcam antibodies for CBLIF
- Invitrogen Antibodies for CBLIF (AFLGC-CBLIF)
-
Custom Antibody ServicesProSci Antibodies for CBLIF
- Sino Biological Antibodies for CBLIF
Protein products for research
- Search Origene for MassSpec and Protein Over-expression Lysates for CBLIF
- Origene Custom Protein Services for CBLIF
- Sino Biological Recombinant Proteins for CBLIF
- Sino Biological Cell Lysates for CBLIF
- ProSpec Recombinant Proteins for CBLIF
-
Abcam proteins for CBLIF
Assay products for research
- G Biosciences Immunotag™ Human GIF (Gastric Intrinsic Factor) ELISA
- RayBiotech Custom Human Gastric Intrinsic Factor ELISA
-
Custom Assay ServicesOriGene ELISA Kits for CBLIF
- Novus Biologicals ELISA Kits for CBLIF
-
Boster Bio ELISA Kits for CBLIF
- Sino Biological Assays for CBLIF
No data available for DME Specific Peptides for CBLIF Gene
Domains & Families for CBLIF Gene
Gene Families for CBLIF Gene
- Human Protein Atlas (HPA):
-
- Disease related genes
- Predicted secreted proteins
Protein Domains for CBLIF Gene
- InterPro:
- Blocks:
-
- Eukaryotic cobalamin-binding protein
Suggested Antigen Peptide Sequences for CBLIF Gene
- GenScript: Design optimal peptide antigens:
-
- Intrinsic factor (IF_HUMAN)
Graphical View of Domain Structure for InterPro Entry
P27352- Family:
-
- Belongs to the eukaryotic cobalamin transport proteins family.
Function for CBLIF Gene
Molecular function for CBLIF Gene
- UniProtKB/Swiss-Prot Function:
- Promotes absorption of the essential vitamin cobalamin (Cbl) in the ileum. After interaction with CUBN, the CBLIF-cobalamin complex is internalized via receptor-mediated endocytosis.
Phenotypes From GWAS Catalog for CBLIF Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005515 | protein binding | IPI | 20237569 |
| GO:0031419 | cobalamin binding | IBA,IDA | 14695536 |
Phenotypes for CBLIF Gene
- MGI mutant phenotypes for CBLIF:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for CBLIF:
-
- Increased vaccinia virus (VACV) infection
- shRNA abundance <= 50%
- no effect
- Decreased vaccinia virus (VACV) infection
- Resistant to vaccinia virus (VACV-A4L) infection
- Increased shRNA abundance (Z-score > 2)
- Decreased viability in non-small-cell lung cancer (NSCLC) lineage
- Decreased shRNA abundance (Z-score < -2)
- Synthetic lethal with c-Myc after tamoxifen stimulation
- Increased the percentage of infected cells
Animal Models for CBLIF Gene
- MGI Knock Outs for CBLIF:
-
- Cblif Cblif<tm1a(KOMP)Wtsi>
Animal Models for research
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for CBLIF - Starting at $85 >
- * CBLIF CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for CBLIF
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for CBLIF
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for CBLIF
- Browse OriGene Inhibitory RNA Products For CBLIF
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for CBLIF
Clone products for research
- Applied Biological Materials (abm): Clones for CBLIF - Starting at $45 >
- * CBLIF as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
- Sino Biological Human cDNA Clone for CBLIF
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for CBLIF
Cell Lines for research
-
Horizon Cell Lines for CBLIF
No data available for Enzyme Numbers (IUBMB) , miRNA , Transcription Factor Targets and HOMER Transcription for CBLIF Gene
Localization for CBLIF Gene
Subcellular locations from UniProtKB/Swiss-Prot for CBLIF Gene
- Secreted.
| Compartment | Confidence |
|---|---|
| plasma membrane | 5 |
| extracellular | 5 |
| endosome | 5 |
| lysosome | 4 |
| nucleus | 2 |
| cytoskeleton | 1 |
| mitochondrion | 1 |
| endoplasmic reticulum | 1 |
| cytosol | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005576 | extracellular region | TAS | -- |
| GO:0005615 | extracellular space | IBA,IDA | 14695536 |
| GO:0005768 | endosome | TAS | -- |
| GO:0005902 | microvillus | IDA | 8886952 |
| GO:0016324 | apical plasma membrane | IDA | 8886952 |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for CBLIF Gene
Pathways & Interactions for CBLIF Gene
Pathways by source for CBLIF Gene
2 BioSystems pathways for CBLIF Gene
1 KEGG pathway for CBLIF Gene
Interacting Proteins for CBLIF Gene
Selected Interacting proteins:
P27352-IF_HUMAN
ENSP00000257248
for CBLIF Gene via
UniProtKB
STRING
IID
GPS-Prot Interaction Network for CBLIF
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006811 | ion transport | IEA | -- |
| GO:0006824 | cobalt ion transport | IEA | -- |
| GO:0009235 | cobalamin metabolic process | TAS | -- |
| GO:0015889 | cobalamin transport | IMP | 15738392 |
No data available for SIGNOR curated interactions for CBLIF Gene
Transcripts for CBLIF Gene
mRNA/cDNA for CBLIF Gene
- 1 REFSEQ mRNAs :
- 5 NCBI additional mRNA sequence :
- 5 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000257248 1511 nts (view in UCSC)
- ENST00000525058 1623 nts (view in UCSC)
- ENST00000532070 977 nts (view in UCSC)
- ENST00000533067 386 nts (view in UCSC)
- ENST00000533847 745 nts (view in UCSC)
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for CBLIF - Starting at $85 >
- * CBLIF CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for CBLIF
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for CBLIF
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for CBLIF
- Browse OriGene Inhibitory RNA Products For CBLIF
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for CBLIF
Clone products for research
- Applied Biological Materials (abm): Clones for CBLIF - Starting at $45 >
- * CBLIF as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
- Sino Biological Human cDNA Clone for CBLIF
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for CBLIF
Relevant External Links for CBLIF Gene
- GeneLoc Exon Structure for
- CBLIF
Expression for CBLIF Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for CBLIF
SOURCE GeneReport for Unigene cluster for CBLIF Gene:
Hs.110014mRNA Expression by UniProt/SwissProt for CBLIF Gene:
P27352-IF_HUMAN
Tissue specificity:
Gastric mucosa.
Evidence on tissue expression from TISSUES for CBLIF Gene
- Stomach(4.9)
- Intestine(4.4)
Phenotype-based relationships between genes and organs from Gene ORGANizer for CBLIF Gene
Germ Layers:
- ectoderm
- endoderm
- mesoderm
Systems:
- cardiovascular
- digestive
- immune
- integumentary
- nervous
- skeleton
Regions:
Head and neck:
- brain
- cerebellum
- head
Abdomen:
- intestine
- large intestine
- small intestine
- stomach
Limb:
- femur
- lower limb
- thigh
General:
- blood
- peripheral nerve
- peripheral nervous system
- red blood cell
- skin
- spinal column
- vertebrae
- white blood cell
Primer products for research
-
OriGene qPCR primer pairs for CBLIF
-
OriGene qPCR primer pairs and template standards for CBLIF
No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression and Protein tissue co-expression partners for CBLIF Gene
Orthologs for CBLIF Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | GIF 29 30 |
|
OneToOne | |
| Mouse (Mus musculus) |
Mammalia | Gif 29 30 |
|
OneToOne | |
| Cblif 16 |
|
||||
| Cow (Bos Taurus) |
Mammalia | GIF 29 30 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Gif 29 |
|
||
| Dog (Canis familiaris) |
Mammalia | GIF 29 30 |
|
OneToOne | |
| Oppossum (Monodelphis domestica) |
Mammalia | GIF 30 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | GIF 30 |
|
OneToOne | |
| Chicken (Gallus gallus) |
Aves | GIF 29 30 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | GIF 30 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | gif 29 |
|
||
| Sea Squirt (Ciona savignyi) |
Ascidiacea | -- 30 |
|
OneToMany |
- Species where no ortholog for CBLIF was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
- Zebrafish (Danio rerio)
Evolution for CBLIF Gene
- ENSEMBL:
- Gene Tree for CBLIF (if available)
- TreeFam:
- Gene Tree for CBLIF (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for CBLIF: view image
- Alliance of Genome Resources:
- Additional Orthologs for CBLIF
Paralogs for CBLIF Gene
Variants for CBLIF Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for CBLIF Gene
| SNP ID | Clinical significance and condition | Chr 11 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| 1005545 | Uncertain Significance: Intrinsic factor deficiency | 59,835,817(-) |
G/C NM_005142.3(CBLIF):c.1064C>G (p.Pro355Arg) |
MISSENSE | |
| 1008760 | Uncertain Significance: Intrinsic factor deficiency | 59,831,680(-) |
T/A NM_005142.3(CBLIF):c.1190A>T (p.Glu397Val) |
MISSENSE | |
| 1038547 | Uncertain Significance: Intrinsic factor deficiency | 59,842,508(-) |
G/T NM_005142.3(CBLIF):c.446C>A (p.Ala149Glu) |
MISSENSE | |
| 1040504 | Uncertain Significance: Intrinsic factor deficiency | 59,837,291(-) |
T/A NM_005142.3(CBLIF):c.754A>T (p.Met252Leu) |
MISSENSE | |
| 877195 | Uncertain Significance: Intrinsic factor deficiency | 59,845,428(-) |
A/G NM_005142.3(CBLIF):c.26T>C (p.Leu9Pro) |
MISSENSE |
All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).
Residual Variation Intolerance Score:
82.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
2.35;
41.73% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for CBLIF Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for CBLIF Gene
Disorders for CBLIF Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| intrinsic factor deficiency |
|
|
| congenital intrinsic factor deficiency |
|
|
| megaloblastic anemia |
|
|
| pernicious anemia |
|
|
| vitamin b12 deficiency |
|
|
Search CBLIF in MalaCards
View complete list of genes associated with diseases
UniProtKB/Swiss-Prot
IF_HUMAN- Hereditary intrinsic factor deficiency (IFD) [MIM:261000]: Autosomal recessive disorder characterized by megaloblastic anemia. {ECO:0000269 PubMed:15738392}. Note=The disease is caused by variants affecting the gene represented in this entry.
Additional Disease Information for CBLIF
- Atlas
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
- Open Targets Platform
No data available for Genatlas for CBLIF Gene
Publications for CBLIF Gene
- Hereditary juvenile cobalamin deficiency caused by mutations in the intrinsic factor gene. (PMID: 15738392) Tanner SM … de la Chapelle A (Proceedings of the National Academy of Sciences of the United States of America 2005) 3 4 22 72
- A genetic polymorphism in the coding region of the gastric intrinsic factor gene (GIF) is associated with congenital intrinsic factor deficiency. (PMID: 14695536) Gordon MM … Alpers DH (Human mutation 2004) 3 4 22 72
- Structural basis for receptor recognition of vitamin-B(12)-intrinsic factor complexes. (PMID: 20237569) Andersen CB … Andersen GR (Nature 2010) 3 4 22
- Crystal structure of human intrinsic factor: cobalamin complex at 2.6-A resolution. (PMID: 17954916) Mathews FS … Sukumar N (Proceedings of the National Academy of Sciences of the United States of America 2007) 3 4 22
- Human gastric intrinsic factor: characterization of cDNA and genomic clones and localization to human chromosome 11. (PMID: 2071148) Hewitt JE … Alpers DH (Genomics 1991) 2 3 4
Products for CBLIF Gene
- Custom Antibody ServicesOriGene Antibodies for CBLIF
- Custom Assay ServicesOriGene ELISA Kits for CBLIF
- Search Origene for MassSpec and Protein Over-expression Lysates for CBLIF
- Origene Custom Protein Services for CBLIF
- Origene shrna, sirna, and RNAi products in human, mouse, rat for CBLIF
- Browse OriGene Inhibitory RNA Products For CBLIF
- OriGene qPCR primer pairs for CBLIF
- OriGene qPCR primer pairs and template standards for CBLIF
- OriGene CRISPR knockouts for CBLIF
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For CBLIF
- Sino Biological Human cDNA Clone for CBLIF
- Sino Biological Recombinant Proteins for CBLIF
- Sino Biological Cell Lysates for CBLIF
- Sino Biological Antibodies for CBLIF
- Sino Biological Assays for CBLIF
- Browse Recombinant Proteins
- Browse Antibodies
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for CBLIF
- Novus Biologicals proteins and lysates for CBLIF
- Novus Biologicals ELISA Kits for CBLIF
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Abcam antibodies for CBLIF
- Abcam proteins for CBLIF
- Find your target
- Browse Primary Antibodies
- Browse Conjugated Primary Antibodies
- Browse Secondary Antibodies
- Browse ELISA Kits
- Browse Matched Antibody Pairs
- Browse Proteins and Peptides
- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
- Browse Recombinant Antibodies
- VectorBuilder Custom and pre-made DNA vectors for CBLIF (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for CBLIF (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for CBLIF (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for CBLIF CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for CBLIF
- antibodies-online: Show 17 available Intrinsic Factor Antibodies ranked by validation data
- Compare Top Intrinsic Factor Antibodies
- antibodies-online: Show 39 available Intrinsic Factor Elisa Kits ranked by validation data
- Compare Top Intrinsic Factor Elisa Kits
- Quality Products:
- antibodies-online: Show 18 available Intrinsic Factor Proteins ranked by validation data
- Compare Top Intrinsic Factor Proteins
- Custom Antibody ServicesProSci Antibodies for CBLIF
- Search for CBLIF Proteins at ProSci
- Horizon Cell Lines for CBLIF
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for CBLIF
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for CBLIF
- Search GeneCopoeia for miRNA 3'UTR Target clone products for CBLIF
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for CBLIF
Sources for CBLIF Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM® (Updated: 05-Apr-2021)
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) ASD
- (27) SAGE
- (28) SOURCE
- (29) HomoloGene
- (30) PanEnsembl
- (31) euGenes
- (32) SGD
- (33) FlyBase
- (34) WormBase
- (35) Pseudogene
- (36) DGV
- (37) dbSNP
- (38) GenAtlas
- (39) HGMD
- (40) GAD
- (41) BGMUT
- (42) HuGE
- (43) Atlas
- (44) GenBank
- (45) HORDE
- (46) HUGE
- (47) IMGT
- (48) Leiden
- (49) miRBase
- (50) DME
- (51) OriGene
- (52) PubMed
- (53) R&D Systems
- (54) Tocris
- (55) Abcam
- (56) Novus Biologicals
- (57) ProSpec
- (58) Sino Biological
- (59) GenScript
- (60) Qiagen
- (61) OCA
- (62) Proteopedia
- (63) MOPED
- (64) neXtProt
- (65) Reactome
- (66) GeneGo (Thomson Reuters)
- (67) DISEASES
- (68) SIMAP
- (69) GenomeRNAi
- (70) LifeMap
- (71) miRTarBase
- (72) MalaCards
- (73) Invitrogen
- (74) BitterDB
- (75) ESI-BIO
- (76) RefSeq
- (77) BioSystems
- (78) MaxQB
- (79) IUPHAR
- (80) BioGPS
- (81) Illumina
- (82) COMPARTMENTS
- (83) HOMER
- (84) PaxDb
- (85) ApexBio
- (86) Addgene
- (87) antibodies-online
- (88) CYP
- (89) NONCODE
- (90) TreeFam
- (91) PathCards
- (92) GeneReviews
- (93) GeneTex
- (94) Taconic Biosciences
- (95) GTEx
- (96) ProteomicsDB
- (97) SCBT
- (98) DGIdb
- (99) ClinicalTrials
- (100) RVIS
- (101) SIGNOR
- (102) diseasecard
- (103) NIH Rare Diseases
- (104) Orphanet
- (105) UMLS
- (106) GTR
- (107) Disease Ontology
- (108) MedlinePlus Genetics
- (109) MeSH
- (110) MedlinePlus
- (111) CDC
- (112) NINDS
- (113) NCBI Bookshelf
- (114) ClinVar
- (115) Gene Damage Index
- (116) HPO
- (117) UDN
- (118) VISTA
- (119) FANTOM5
- (120) ENCODE
- (121) ProSci
- (122) Horizon
- (123) The Signaling Pathways Project (SPP)
- (124) IID
- (125) VectorBuilder
- (126) SNPedia
- (127) BRCA Exchange
- (128) CIViC
- (129) ProteoGenix
- (130) dbSUPER
- (131) TISSUES
- (132) Gene ORGANizer
- (133) abm
- (134) Human Protein Atlas
- (135) GWAS Catalog
- (136) Monarch Initiative
- (137) DataMed
- (138) HumanCyc
- (139) UCNEbase
- (140) EPDnew
- (141) Applied Biosystems
- (142) GlyConnect
- (143) Aminode
- (144) GeneCopoeia
- (145) GPS-Prot
- (146) RNAcentral
- (147) LncRNADisease
- (148) LOVD
- (149) miR2Disease
- (150) DiseaseEnhancer
- (151) Boster Bio
- (152) Biorbyt
- (153) Biocompare
- (154) Mastermind
- (155) CTD^2 Dashboard
- (156) CraniofacialAtlas
- (157) GeneImprint
- (158) Synthego
- (159) ENA
- (160) GtRNAdb
- (161) LncBase
- (162) LncBook
- (163) LNCipedia
- (164) Modomics
- (165) PDBe
- (166) Rfam
- (167) SILVA
- (168) snOPY
- (169) SRPDB
- (170) GENCODE
- (171) TarBase
- (172) Open Targets Platform
- (173) 5SRRNADB
- (174) snoDB
- (175) MirGeneDB
- (176) Alliance of Genome Resources