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Aliases for CATIP Gene

Aliases for CATIP Gene

  • Ciliogenesis Associated TTC17 Interacting Protein 2 3 5
  • C2orf62 3 4
  • Ciliogenesis-Associated TTC17-Interacting Protein 3
  • Chromosome 2 Open Reading Frame 62 2

External Ids for CATIP Gene

Previous HGNC Symbols for CATIP Gene

  • C2orf62

Previous GeneCards Identifiers for CATIP Gene

  • GC02P219222

Summaries for CATIP Gene

GeneCards Summary for CATIP Gene

CATIP (Ciliogenesis Associated TTC17 Interacting Protein) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include calmodulin binding.

UniProtKB/Swiss-Prot for CATIP Gene

  • Plays a role in primary ciliogenesis by modulating actin polymerization.

Additional gene information for CATIP Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CATIP Gene

Genomics for CATIP Gene

GeneHancer (GH) Regulatory Elements for CATIP Gene

Promoters and enhancers for CATIP Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH02I218356 Promoter/Enhancer 1.6 EPDnew Ensembl ENCODE 550.8 +0.3 256 1.8 ELF3 PKNOX1 ARID4B SIN3A BMI1 ZNF48 RAD21 SCRT2 CREM THAP11 CATIP GC02M218355 CATIP-AS2 ENSG00000261338 TMBIM1 AAMP PNKD SLC11A1
GH02I218354 Enhancer 0.8 ENCODE 550.8 -1.7 -1665 0.5 MLX ARID4B ZNF48 RARA CREM THAP11 SP5 PPARG KAT8 RAD51 RPL19P5 GC02M218355 CATIP PNKD TMBIM1 AAMP SLC11A1 CFAP65 CATIP-AS2
GH02I218359 Enhancer 1 Ensembl ENCODE 13.3 +5.1 5067 5 HDAC1 FOXA2 TCF12 ZNF766 EGR1 SCRT2 ATF7 EGR2 CEBPB REST CATIP ENSG00000261338 PNKD CATIP-AS2 CATIP-AS1 GC02M218358
GH02I218366 Promoter/Enhancer 2 FANTOM5 Ensembl ENCODE dbSUPER 4.7 +13.0 13043 6.8 HDGF SMAD1 ATF1 SIN3A YY1 ETS1 POLR2B ZNF207 ZNF143 ATF7 CATIP-AS1 GC02M218358 SLC11A1 ENSG00000261338 ARPC2 CXCR2 CXCR1 CATIP PNKD CNOT9
GH02I218381 Promoter/Enhancer 1.3 EPDnew Ensembl ENCODE 4.9 +26.4 26372 3.6 CTCF FOXA2 HLF ZSCAN4 CEBPB MAX CEBPG FOXA1 POLR2A GLIS1 SLC11A1 TMBIM1 AAMP PNKD CATIP CTDSP1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around CATIP on UCSC Golden Path with GeneCards custom track

Genomic Locations for CATIP Gene

Genomic Locations for CATIP Gene
11,279 bases
Plus strand

Genomic View for CATIP Gene

Genes around CATIP on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CATIP Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CATIP Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CATIP Gene

Proteins for CATIP Gene

  • Protein details for CATIP Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Ciliogenesis-associated TTC17-interacting protein
    Protein Accession:

    Protein attributes for CATIP Gene

    387 amino acids
    Molecular mass:
    43900 Da
    Quaternary structure:
    • Interacts with TTC17.

neXtProt entry for CATIP Gene

Post-translational modifications for CATIP Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CATIP Gene

No data available for DME Specific Peptides for CATIP Gene

Domains & Families for CATIP Gene

Gene Families for CATIP Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for CATIP Gene


Graphical View of Domain Structure for InterPro Entry



  • Belongs to the CATIP family.
  • Belongs to the CATIP family.
genes like me logo Genes that share domains with CATIP: view

No data available for Suggested Antigen Peptide Sequences for CATIP Gene

Function for CATIP Gene

Molecular function for CATIP Gene

UniProtKB/Swiss-Prot Function:
Plays a role in primary ciliogenesis by modulating actin polymerization.

Gene Ontology (GO) - Molecular Function for CATIP Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 24475127
genes like me logo Genes that share ontologies with CATIP: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for CATIP Gene

Localization for CATIP Gene

Subcellular locations from UniProtKB/Swiss-Prot for CATIP Gene

Nucleus. Cytoplasm. Cell membrane. Cytoplasm, cytoskeleton. Note=Colocalized with TTC17 at F-actin rich zones and at dynamic plasma membrane protrusions.

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for CATIP gene
Compartment Confidence
plasma membrane 5
cytoskeleton 5
nucleus 5
cytosol 2
peroxisome 1

Gene Ontology (GO) - Cellular Components for CATIP Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA,IDA 24475127
GO:0005737 cytoplasm IDA,IEA 24475127
GO:0005856 cytoskeleton IEA --
GO:0005886 plasma membrane IEA,IDA 24475127
GO:0015629 actin cytoskeleton IDA 24475127
genes like me logo Genes that share ontologies with CATIP: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for CATIP Gene

Pathways & Interactions for CATIP Gene

SuperPathways for CATIP Gene

No Data Available

Gene Ontology (GO) - Biological Process for CATIP Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0030030 cell projection organization IEA --
GO:0030041 actin filament polymerization IMP 24475127
GO:0044782 cilium organization IMP 24475127
genes like me logo Genes that share ontologies with CATIP: view

No data available for Pathways by source and SIGNOR curated interactions for CATIP Gene

Drugs & Compounds for CATIP Gene

No Compound Related Data Available

Transcripts for CATIP Gene

mRNA/cDNA for CATIP Gene

CRISPR Products

Inhibitory RNA Products

Alternative Splicing Database (ASD) splice patterns (SP) for CATIP Gene

ExUns: 1a · 1b ^ 2a · 2b ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7 ^ 8a · 8b ^ 9 ^ 10
SP1: - - -
SP2: - - -

Relevant External Links for CATIP Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for CATIP Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for CATIP Gene

mRNA differential expression in normal tissues according to GTEx for CATIP Gene

This gene is overexpressed in Testis (x7.5), Whole Blood (x5.7), Kidney - Cortex (x4.8), Fallopian Tube (x4.3), and Thyroid (x4.2).

Protein differential expression in normal tissues from HIPED for CATIP Gene

This gene is overexpressed in Bone marrow stromal cell (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for CATIP Gene

Protein tissue co-expression partners for CATIP Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of CATIP Gene:


mRNA Expression by UniProt/SwissProt for CATIP Gene:

Tissue specificity: Strongly expressed in round and elongating spermatids, weakly in pachytene spermatocytes. Expressed in Leydig cells (at protein level). Expressed in testis, placenta, prostate and lung, and moderately in ovary and brain.

Evidence on tissue expression from TISSUES for CATIP Gene

  • Nervous system(4.1)
genes like me logo Genes that share expression patterns with CATIP: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and Phenotype-based relationships between genes and organs from Gene ORGANizer for CATIP Gene

Orthologs for CATIP Gene

This gene was present in the common ancestor of chordates.

Orthologs for CATIP Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia CATIP 33
  • 99.48 (n)
C2orf62 34
  • 99 (a)
(Bos Taurus)
Mammalia CATIP 33
  • 84.96 (n)
C2orf62 34
  • 79 (a)
(Rattus norvegicus)
Mammalia LOC690437 33
  • 78.66 (n)
(Canis familiaris)
Mammalia C2orf62 34
  • 72 (a)
(Monodelphis domestica)
Mammalia C2orf62 34
  • 51 (a)
(Mus musculus)
Mammalia Gm216 34
  • 51 (a)
(Gallus gallus)
Aves CATIP 33
  • 54.44 (n)
C2orf62 34
  • 42 (a)
(Anolis carolinensis)
Reptilia C2orf62 34
  • 44 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100495462 33
  • 55.52 (n)
(Danio rerio)
Actinopterygii catip 33
  • 54.12 (n)
C6H2orf62 34
  • 40 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 34
  • 37 (a)
Species where no ortholog for CATIP was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CATIP Gene

Gene Tree for CATIP (if available)
Gene Tree for CATIP (if available)

Paralogs for CATIP Gene

No data available for Paralogs for CATIP Gene

Variants for CATIP Gene

Sequence variations from dbSNP and Humsavar for CATIP Gene

SNP ID Clin Chr 02 pos Variation AA Info Type
rs1000097055 -- 218,366,957(+) A/G intron_variant
rs1000149248 -- 218,367,349(+) T/C intron_variant
rs1000726209 -- 218,358,816(+) C/T intron_variant
rs1000864296 -- 218,365,105(+) A/C intron_variant
rs1001614594 -- 218,362,556(+) A/G intron_variant

Structural Variations from Database of Genomic Variants (DGV) for CATIP Gene

Variant ID Type Subtype PubMed ID
esv2763102 CNV loss 21179565
nsv519829 CNV loss 19592680

Variation tolerance for CATIP Gene

Residual Variation Intolerance Score: 68.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.02; 37.22% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for CATIP Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CATIP Gene

Disorders for CATIP Gene

Additional Disease Information for CATIP

No disorders were found for CATIP Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CATIP Gene

Publications for CATIP Gene

  1. C2orf62 and TTC17 are involved in actin organization and ciliogenesis in zebrafish and human. (PMID: 24475127) Bontems F … Lane L (PloS one 2014) 2 3 4 58
  2. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T … Vidal M (Cell 2014) 3 58
  3. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PMID: 21832049) Oláh J … Ovádi J (The Journal of biological chemistry 2011) 3 58
  4. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PMID: 17207965) Lamesch P … Vidal M (Genomics 2007) 3 58
  5. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PMID: 15815621) Hillier LW … Wilson RK (Nature 2005) 4 58

Products for CATIP Gene

Sources for CATIP Gene

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