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The protein encoded by this gene is a zinc finger transcription factor. The encoded protein may function as a tumor suppressor, and single nucleotide polymorphisms in this gene are associated with blood pressure variation. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Jul 2012] See more...
Aliases for CASZ1 Gene
Aliases for CASZ1 Gene
External Ids for CASZ1 Gene
- HGNC: 26002
- NCBI Entrez Gene: 54897
- Ensembl: ENSG00000130940
- OMIM®: 609895
- UniProtKB/Swiss-Prot: Q86V15
Previous GeneCards Identifiers for CASZ1 Gene
- GC01M009850
Summaries for CASZ1 Gene
-
The protein encoded by this gene is a zinc finger transcription factor. The encoded protein may function as a tumor suppressor, and single nucleotide polymorphisms in this gene are associated with blood pressure variation. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Jul 2012]
GeneCards Summary for CASZ1 Gene
CASZ1 (Castor Zinc Finger 1) is a Protein Coding gene. Diseases associated with CASZ1 include Dystonia, Dopa-Responsive, Due To Sepiapterin Reductase Deficiency and Chromosome 1P36 Deletion Syndrome.
UniProtKB/Swiss-Prot Summary for CASZ1 Gene
-
Transcriptional activator (PubMed:23639441, PubMed:27693370). Involved in vascular assembly and morphogenesis through direct transcriptional regulation of EGFL7 (PubMed:23639441).
Additional gene information for CASZ1 Gene
No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for CASZ1 Gene
Genomics for CASZ1 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for CASZ1 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around CASZ1 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for CASZ1
- Top Transcription factor binding sites by QIAGEN in the CASZ1 gene promoter:
-
- AREB6
- FOXD3
- NF-AT
- NF-AT1
- NF-AT2
- NF-AT3
- NF-AT4
- Nkx2-5
- POU3F2
- SRY
Genomic Locations for CASZ1 Gene
Latest Assembly
- chr1:10,636,604-10,796,650
- (GRCh38/hg38)
- Size:
- 160,047 bases
- Orientation:
- Minus strand
Previous Assembly
- chr1:10,696,661-10,856,703
- (GRCh37/hg19 by Entrez Gene)
- Size:
- 160,043 bases
- Orientation:
- Minus strand
Genomic View for CASZ1 Gene
Genes around CASZ1 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 1p36.22 by HGNC
- 1p36.22 by Entrez Gene
- 1p36.22 by Ensembl
CASZ1 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for CASZ1 Gene
Proteins for CASZ1 Gene
-
Protein details for CASZ1 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q86V15-CASZ1_HUMAN
- Recommended name:
- Zinc finger protein castor homolog 1
- Protein Accession:
- Q86V15
- Q078S9
- Q2EN02
- Q5T9S1
- Q6ZNM8
- Q8WX49
- Q8WX50
- Q9BT16
- Q9NXC6
Protein attributes for CASZ1 Gene
- Size:
- 1759 amino acids
- Molecular mass:
- 190069 Da
- Quaternary structure:
- No Data Available
- SequenceCaution:
-
- Sequence=ABD14411.1; Type=Erroneous translation; Note=Wrong choice of CDS.; Evidence={ECO:0000305}; Sequence=BAA91089.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305}; Sequence=BAC85474.1; Type=Erroneous translation; Note=Wrong choice of CDS.; Evidence={ECO:0000305};
- Miscellaneous:
-
- Endothelial cells depleted in CASZ1 by siRNAs display dramatic alterations in adhesion, morphology and sprouting; normal behavior can be rescued by restoration of EGFL7 expression. The defects are in part due to diminished RhoA expression and impaired focal adhesion localization.
Protein Expression for CASZ1 Gene
Post-translational modifications for CASZ1 Gene
Other Protein References for CASZ1 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibodies for research
- LifeSpan BioSciences CASZ1 Antibody
-
Custom Antibody ServicesOriGene Antibodies for CASZ1
- Novus Biologicals Antibodies for CASZ1
- Invitrogen Antibodies for CASZ1 (AFLGC-CASZ1)
-
Boster Bio Antibodies for CASZ1
-
Custom Antibody ServicesProSci Antibodies for CASZ1
-
Santa Cruz Biotechnology (SCBT) Antibodies for CASZ1
- Sino Biological Antibodies for CASZ1
Protein products for research
-
OriGene Purified Proteins for CASZ1
- Search Origene for MassSpec and Protein Over-expression Lysates for CASZ1
- Origene Custom Protein Services for CASZ1
Assay products for research
No data available for DME Specific Peptides for CASZ1 Gene
Domains & Families for CASZ1 Gene
Gene Families for CASZ1 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
- Transcription factors
Protein Domains for CASZ1 Gene
- InterPro:
Suggested Antigen Peptide Sequences for CASZ1 Gene
- GenScript: Design optimal peptide antigens:
-
- Zinc finger protein 693 (CASZ1_HUMAN)
- Castor zinc finger 1 (Q5T9S0_HUMAN)
No data available for Graphical View of Domain Structure and UniProtKB/Swiss-Prot for CASZ1 Gene
Function for CASZ1 Gene
Molecular function for CASZ1 Gene
- UniProtKB/Swiss-Prot Function:
- Transcriptional activator (PubMed:23639441, PubMed:27693370). Involved in vascular assembly and morphogenesis through direct transcriptional regulation of EGFL7 (PubMed:23639441).
Phenotypes From GWAS Catalog for CASZ1 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000977 | RNA polymerase II regulatory region sequence-specific DNA binding | IDA | 27693370 |
| GO:0001228 | DNA-binding transcription activator activity, RNA polymerase II-specific | IDA | 27693370 |
| GO:0003677 | DNA binding | IEA | -- |
| GO:0046872 | metal ion binding | IEA | -- |
Phenotypes for CASZ1 Gene
- MGI mutant phenotypes for CASZ1:
- inferred from 4 alleles
- GenomeRNAi human phenotypes for CASZ1:
Animal Models for CASZ1 Gene
- MGI Knock Outs for CASZ1:
-
- Casz1 Casz1<tm1b(EUCOMM)Hmgu>
Animal Models for research
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for CASZ1 - Starting at $85 >
- * CASZ1 CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for CASZ1
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for CASZ1
-
Santa Cruz Biotechnology (SCBT) CRISPR for CASZ1
miRNA for CASZ1 Gene
- miRTarBase miRNAs that target CASZ1
-
- hsa-miR-151a-5p (MIRT053612)
- hsa-miR-4665-3p (MIRT487870)
- hsa-miR-486-3p (MIRT487871)
- hsa-miR-6825-5p (MIRT487872)
- hsa-miR-6883-5p (MIRT487873)
- hsa-miR-6785-5p (MIRT487874)
- hsa-miR-4728-5p (MIRT487875)
- hsa-miR-149-3p (MIRT487876)
- hsa-miR-885-3p (MIRT487877)
- hsa-miR-4706 (MIRT487878)
- hsa-miR-4749-5p (MIRT487879)
- hsa-miR-3195 (MIRT487880)
- hsa-miR-3648 (MIRT487881)
- hsa-miR-423-5p (MIRT487882)
- hsa-miR-3184-5p (MIRT487883)
- hsa-miR-6775-5p (MIRT487884)
- hsa-miR-5090 (MIRT487885)
- hsa-miR-6889-5p (MIRT487886)
- hsa-miR-6777-5p (MIRT487887)
- hsa-miR-1908-3p (MIRT487888)
- hsa-miR-6784-5p (MIRT487889)
- hsa-miR-7975 (MIRT549031)
- hsa-miR-4540 (MIRT549032)
- hsa-miR-524-5p (MIRT549033)
- hsa-miR-520d-5p (MIRT549034)
- hsa-miR-4670-3p (MIRT549035)
- hsa-miR-648 (MIRT549036)
- hsa-miR-6838-3p (MIRT549037)
- hsa-miR-4517 (MIRT549038)
- hsa-miR-19b-3p (MIRT549039)
- hsa-miR-19a-3p (MIRT549040)
- hsa-miR-574-5p (MIRT569200)
- hsa-miR-4455 (MIRT569201)
- hsa-miR-5010-3p (MIRT569202)
- hsa-miR-147a (MIRT569203)
- hsa-miR-8068 (MIRT569204)
- hsa-miR-6818-5p (MIRT569205)
- hsa-miR-6867-5p (MIRT569206)
- hsa-miR-33a-3p (MIRT569207)
- mmu-miR-466m-3p (MIRT584463)
- mmu-miR-466o-3p (MIRT584464)
- mmu-miR-669f-3p (MIRT590432)
- mmu-miR-467f (MIRT590433)
- mmu-miR-466f-3p (MIRT590434)
- mmu-miR-466d-3p (MIRT590435)
- mmu-miR-466e-3p (MIRT590436)
- mmu-miR-467g (MIRT590437)
- mmu-miR-466a-3p (MIRT590438)
- mmu-miR-297b-3p (MIRT590439)
- mmu-miR-376c-3p (MIRT590440)
- mmu-miR-129-5p (MIRT594147)
- mmu-miR-290a-5p (MIRT594148)
- mmu-miR-292a-5p (MIRT594149)
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for CASZ1
- Browse OriGene Inhibitory RNA Products For CASZ1
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for CASZ1
Clone products for research
- Applied Biological Materials (abm): Clones for CASZ1 - Starting at $45 >
- * CASZ1 as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
- Sino Biological Human cDNA Clone for CASZ1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for CASZ1
Cell Lines for research
-
Horizon Cell Lines for CASZ1
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for CASZ1 Gene
Localization for CASZ1 Gene
Subcellular locations from UniProtKB/Swiss-Prot for CASZ1 Gene
- Nucleus.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| cytosol | 4 |
| plasma membrane | 1 |
| extracellular | 1 |
| cytoskeleton | 1 |
| mitochondrion | 1 |
| peroxisome | 1 |
| endoplasmic reticulum | 1 |
| endosome | 1 |
| golgi apparatus | 1 |
- Nucleoplasm (3)
- Cytosol (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000785 | chromatin | IDA | 27693370 |
| GO:0005634 | nucleus | IBA | 21873635 |
| GO:0005654 | nucleoplasm | IDA | -- |
| GO:0005829 | cytosol | IDA | -- |
| GO:0043231 | intracellular membrane-bounded organelle | IDA | -- |
Pathways & Interactions for CASZ1 Gene
Interacting Proteins for CASZ1 Gene
GPS-Prot Interaction Network for CASZ1
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006355 | regulation of transcription, DNA-templated | IBA | 21873635 |
| GO:0007275 | multicellular organism development | IEA | -- |
| GO:0045664 | regulation of neuron differentiation | IBA | 21873635 |
| GO:0045893 | positive regulation of transcription, DNA-templated | IDA | 27693370 |
| GO:0045944 | positive regulation of transcription by RNA polymerase II | IDA | 27693370 |
No data available for Pathways by source and SIGNOR curated interactions for CASZ1 Gene
Transcripts for CASZ1 Gene
mRNA/cDNA for CASZ1 Gene
- 3 REFSEQ mRNAs :
- 13 NCBI additional mRNA sequence :
- 9 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000344008 4405 nts (view in UCSC)
- ENST00000377022 7934 nts (view in UCSC)
- ENST00000447850 695 nts (view in UCSC)
- ENST00000472814 451 nts (view in UCSC)
- ENST00000478524 337 nts (view in UCSC)
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for CASZ1 - Starting at $85 >
- * CASZ1 CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for CASZ1
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for CASZ1
-
Santa Cruz Biotechnology (SCBT) CRISPR for CASZ1
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for CASZ1
- Browse OriGene Inhibitory RNA Products For CASZ1
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for CASZ1
Clone products for research
- Applied Biological Materials (abm): Clones for CASZ1 - Starting at $45 >
- * CASZ1 as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
- Sino Biological Human cDNA Clone for CASZ1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for CASZ1
Relevant External Links for CASZ1 Gene
- GeneLoc Exon Structure for
- CASZ1
Expression for CASZ1 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Limb (Muscoskeletal System)
- Limb Muscle Progenitor Cells Forelimb Myotome
-
Skeletal Muscle (Muscoskeletal System)
- Limb Muscle Progenitor Cells Forelimb Myotome
- Adipose (Muscoskeletal System)
- Bone (Muscoskeletal System)
- Cartilage (Muscoskeletal System)
-
Eye (Sensory Organs)
mRNA differential expression in normal tissues according to GTEx for CASZ1 Gene
This gene is overexpressed in Skin - Sun Exposed (Lower leg) (x5.6) and Skin - Not Sun Exposed (Suprapubic) (x5.3).
This gene is overexpressed in Plasma (29.2), Retina (19.3), and Breast (16.0).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for CASZ1 Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for CASZ1
SOURCE GeneReport for Unigene cluster for CASZ1 Gene:
Hs.439894mRNA Expression by UniProt/SwissProt for CASZ1 Gene:
Q86V15-CASZ1_HUMAN
Tissue specificity:
Expressed in heart, lung, skeletal muscle, pancreas, testis, small intestine, and stomach, but it is not detectable in the adult brain.
Evidence on tissue expression from TISSUES for CASZ1 Gene
- Heart(4.4)
- Intestine(4.3)
- Pancreas(4.2)
- Skin(2.5)
- Eye(2)
Primer products for research
-
OriGene qPCR primer pairs for CASZ1
-
OriGene qPCR primer pairs and template standards for CASZ1
Gene Expression Assays for research
No data available for Phenotype-based relationships between genes and organs from Gene ORGANizer for CASZ1 Gene
Orthologs for CASZ1 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | CASZ1 29 30 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | CASZ1 29 30 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | CASZ1 29 30 |
|
OneToOne | |
| Mouse (Mus musculus) |
Mammalia | Casz1 29 16 30 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Casz1 29 |
|
||
| Platypus (Ornithorhynchus anatinus) |
Mammalia | CASZ1 30 |
|
OneToOne | |
| Oppossum (Monodelphis domestica) |
Mammalia | CASZ1 30 |
|
OneToOne | |
| Chicken (Gallus gallus) |
Aves | CASZ1 29 30 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | CASZ1 30 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | casz1 29 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | casz1 29 30 |
|
OneToOne | |
| wufc21h10 29 |
|
||||
| Fruit Fly (Drosophila melanogaster) |
Insecta | cas 30 |
|
OneToMany | |
| CG7512 30 |
|
OneToMany | |||
| Sea Squirt (Ciona savignyi) |
Ascidiacea | -- 30 |
|
OneToMany | |
| CSA.2018 30 |
|
OneToMany |
- Species where no ortholog for CASZ1 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
Evolution for CASZ1 Gene
- ENSEMBL:
- Gene Tree for CASZ1 (if available)
- TreeFam:
- Gene Tree for CASZ1 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for CASZ1: view image
- Alliance of Genome Resources:
- Additional Orthologs for CASZ1
Paralogs for CASZ1 Gene
Pseudogenes.org Pseudogenes for CASZ1 Gene
No data available for Paralogs for CASZ1 Gene
Variants for CASZ1 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for CASZ1 Gene
| SNP ID | Clinical significance and condition | Chr 01 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs115296720 | Benign: not provided | 10,654,164(-) |
C/T NM_001079843.3(CASZ1):c.1893G>A (p.Lys631=) |
SYNONYMOUS | |
| rs115628512 | Benign: not provided | 10,642,884(-) |
G/A NM_001079843.3(CASZ1):c.4137C>T (p.Pro1379=) |
SYNONYMOUS | |
| rs115739667 | Benign: not provided | 10,644,911(-) |
C/T NM_001079843.3(CASZ1):c.3868+6G>A |
INTRON | |
| rs138985539 | Benign: not provided | 10,660,248(-) |
A/G NM_001079843.3(CASZ1):c.794T>C (p.Val265Ala) |
MISSENSE | |
| rs141461577 | Benign: not provided | 10,649,201(-) |
A/T NM_001079843.3(CASZ1):c.3036-9T>A |
INTRON |
All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).
Residual Variation Intolerance Score:
17.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
6.31;
76.62% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for CASZ1 Gene
SNP Genotyping and Copy Number Assays for research
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CASZ1 Gene
Disorders for CASZ1 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| dystonia, dopa-responsive, due to sepiapterin reductase deficiency |
|
|
| chromosome 1p36 deletion syndrome |
|
|
| speech disorder |
|
|
| neuroblastoma |
|
|
Search CASZ1 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for CASZ1
- Human Genome Epidemiology Navigator
- (HuGE)
- Atlas
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
- Open Targets Platform
No data available for UniProtKB/Swiss-Prot and Genatlas for CASZ1 Gene
Publications for CASZ1 Gene
- Molecular cloning and characterization of human Castor, a novel human gene upregulated during cell differentiation. (PMID: 16631614) Liu Z … Thiele CJ (Biochemical and biophysical research communications 2006) 2 3 4
- CASZ1 loss-of-function mutation associated with congenital heart disease. (PMID: 27693370) Huang RT … Yang YQ (Gene 2016) 3 4
- CASZ1, a candidate tumor-suppressor gene, suppresses neuroblastoma tumor growth through reprogramming gene expression. (PMID: 21252912) Liu Z … Thiele CJ (Cell death and differentiation 2011) 2 3
- Meta-analysis of genome-wide association studies identifies common variants associated with blood pressure variation in east Asians. (PMID: 21572416) Kato N … He J (Nature genetics 2011) 3 40
- Blood pressure and hypertension are associated with 7 loci in the Japanese population. (PMID: 20479155) Takeuchi F … Kato N (Circulation 2010) 3 40
ExternalLinks
Products for CASZ1 Gene
- Custom Antibody ServicesOriGene Antibodies for CASZ1
- Browse OriGene ELISA Kits
- Custom Assay Services
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- Browse OriGene Inhibitory RNA Products For CASZ1
- OriGene qPCR primer pairs for CASZ1
- OriGene qPCR primer pairs and template standards for CASZ1
- OriGene CRISPR knockouts for CASZ1
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For CASZ1
- Sino Biological Human cDNA Clone for CASZ1
- Browse Sino Biological Recombinant Proteins
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- Sino Biological Antibodies for CASZ1
- Browse Sino Biological Assays
- Browse Antibodies
- Browse cDNA Clones
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for CASZ1
- Novus Biologicals proteins and lysates for CASZ1
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Invitrogen Antibodies for CASZ1 (AFLGC-CASZ1)
- VectorBuilder Custom and pre-made DNA vectors for CASZ1 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for CASZ1 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for CASZ1 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for CASZ1 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for CASZ1
- antibodies-online: Show 15 available CASZ1 Antibodies ranked by validation data
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- antibodies-online: Search results for available CASZ1 related products ranked by validation data
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- Santa Cruz Biotechnology (SCBT) Antibodies for CASZ1
- Search Santa Cruz Biotechnology (SCBT) for CASZ1 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for CASZ1
- Horizon Cell Lines for CASZ1
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for CASZ1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for CASZ1
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- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for CASZ1
- Boster Bio Antibodies for CASZ1
- Browse Boster Bio ELISA Kits
Sources for CASZ1 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM® (Updated: 05-Apr-2021)
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) ASD
- (27) SAGE
- (28) SOURCE
- (29) HomoloGene
- (30) PanEnsembl
- (31) euGenes
- (32) SGD
- (33) FlyBase
- (34) WormBase
- (35) Pseudogene
- (36) DGV
- (37) dbSNP
- (38) GenAtlas
- (39) HGMD
- (40) GAD
- (41) BGMUT
- (42) HuGE
- (43) Atlas
- (44) GenBank
- (45) HORDE
- (46) HUGE
- (47) IMGT
- (48) Leiden
- (49) miRBase
- (50) DME
- (51) OriGene
- (52) PubMed
- (53) R&D Systems
- (54) Tocris
- (55) Abcam
- (56) Novus Biologicals
- (57) ProSpec
- (58) Sino Biological
- (59) GenScript
- (60) Qiagen
- (61) OCA
- (62) Proteopedia
- (63) MOPED
- (64) neXtProt
- (65) Reactome
- (66) GeneGo (Thomson Reuters)
- (67) DISEASES
- (68) SIMAP
- (69) GenomeRNAi
- (70) LifeMap
- (71) miRTarBase
- (72) MalaCards
- (73) Invitrogen
- (74) BitterDB
- (75) ESI-BIO
- (76) RefSeq
- (77) BioSystems
- (78) MaxQB
- (79) IUPHAR
- (80) BioGPS
- (81) Illumina
- (82) COMPARTMENTS
- (83) HOMER
- (84) PaxDb
- (85) ApexBio
- (86) Addgene
- (87) antibodies-online
- (88) CYP
- (89) NONCODE
- (90) TreeFam
- (91) PathCards
- (92) GeneReviews
- (93) GeneTex
- (94) Taconic Biosciences
- (95) GTEx
- (96) ProteomicsDB
- (97) SCBT
- (98) DGIdb
- (99) ClinicalTrials
- (100) RVIS
- (101) SIGNOR
- (102) diseasecard
- (103) NIH Rare Diseases
- (104) Orphanet
- (105) UMLS
- (106) GTR
- (107) Disease Ontology
- (108) MedlinePlus Genetics
- (109) MeSH
- (110) MedlinePlus
- (111) CDC
- (112) NINDS
- (113) NCBI Bookshelf
- (114) ClinVar
- (115) Gene Damage Index
- (116) HPO
- (117) UDN
- (118) VISTA
- (119) FANTOM5
- (120) ENCODE
- (121) ProSci
- (122) Horizon
- (123) The Signaling Pathways Project (SPP)
- (124) IID
- (125) VectorBuilder
- (126) SNPedia
- (127) BRCA Exchange
- (128) CIViC
- (129) ProteoGenix
- (130) dbSUPER
- (131) TISSUES
- (132) Gene ORGANizer
- (133) abm
- (134) Human Protein Atlas
- (135) GWAS Catalog
- (136) Monarch Initiative
- (137) DataMed
- (138) HumanCyc
- (139) UCNEbase
- (140) EPDnew
- (141) Applied Biosystems
- (142) GlyConnect
- (143) Aminode
- (144) GeneCopoeia
- (145) GPS-Prot
- (146) RNAcentral
- (147) LncRNADisease
- (148) LOVD
- (149) miR2Disease
- (150) DiseaseEnhancer
- (151) Boster Bio
- (152) Biorbyt
- (153) Biocompare
- (154) Mastermind
- (155) CTD^2 Dashboard
- (156) CraniofacialAtlas
- (157) GeneImprint
- (158) Synthego
- (159) ENA
- (160) GtRNAdb
- (161) LncBase
- (162) LncBook
- (163) LNCipedia
- (164) Modomics
- (165) PDBe
- (166) Rfam
- (167) SILVA
- (168) snOPY
- (169) SRPDB
- (170) GENCODE
- (171) TarBase
- (172) Open Targets Platform
- (173) 5SRRNADB
- (174) snoDB
- (175) MirGeneDB
- (176) Alliance of Genome Resources