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Aliases for CASC22 Gene

Subcategory (RNA class) for CASC22 Gene

non-coding RNA

Quality Score for this RNA gene is

13

Aliases for CASC22 Gene

  • Cancer Susceptibility 22 2 3
  • Cancer Susceptibility 22 (Non-Protein Coding) 2 3 5
  • Cancer Susceptibility Candidate 22 (Non-Protein Coding) 2 3
  • Long Intergenic Non-Protein Coding RNA 1373 2 3
  • LincRNA-ENST00000515084 3
  • TCONS_00024290 3
  • LINC01373 3

External Ids for CASC22 Gene

Previous HGNC Symbols for CASC22 Gene

  • LINC01373

Summaries for CASC22 Gene

GeneCards Summary for CASC22 Gene

CASC22 (Cancer Susceptibility 22) is an RNA Gene, and is affiliated with the non-coding RNA class. Diseases associated with CASC22 include Breast Cancer.

Additional gene information for CASC22 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CASC22 Gene

Genomics for CASC22 Gene

GeneHancer (GH) Regulatory Elements for CASC22 Gene

Promoters and enhancers for CASC22 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH16J052255 Enhancer 0.4 ENCODE 650.7 -2.0 -1984 1.4 SP1 RXRA HNF4A CASC22 LOC105371261 ENSG00000260478
GH16J052208 Enhancer 0.6 VISTA UCNEbase 8.6 -49.1 -49132 1.5 GC16M052210 CASC22 ENSG00000260975 GC16P052188
GH16J052264 Enhancer 0.8 ENCODE dbSUPER 0.4 +7.6 7577 3.5 SOX13 USF1 NANOG NFIA NFIB NFIC LCORL ZNF544 POU5F1 ZNF350 CASC22 LOC105371261 ENSG00000260478 LOC105371262
GH16J052250 Enhancer 0.6 dbSUPER 0.4 -7.0 -6964 1.3 PKNOX1 NANOG JUN BACH1 DPF2 ZEB1 BCL11A ZNF692 CREB1 FOS CASC22 LOC105371261 ENSG00000260478
GH16J052407 Enhancer 0.9 ENCODE 0.1 +149.5 149517 1.7 FOXA2 MLX YY1 ATF7 NFKBIZ RXRA SP5 ZHX2 MIER2 REST TOX3 LOC105371262 CASC22
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around CASC22 on UCSC Golden Path with GeneCards custom track

Genomic Locations for CASC22 Gene

Genomic Locations for CASC22 Gene
chr16:52,258,564-52,280,638
(GRCh38/hg38)
Size:
22,075 bases
Orientation:
Plus strand
chr16:52,292,476-52,314,211
(GRCh37/hg19)

Genomic View for CASC22 Gene

Genes around CASC22 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CASC22 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CASC22 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CASC22 Gene

Proteins for CASC22 Gene

Post-translational modifications for CASC22 Gene

No Post-translational modifications

No data available for DME Specific Peptides for CASC22 Gene

Domains & Families for CASC22 Gene

Gene Families for CASC22 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CASC22: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for CASC22 Gene

Function for CASC22 Gene

Phenotypes From GWAS Catalog for CASC22 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for CASC22 Gene

Localization for CASC22 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for CASC22 Gene

Pathways & Interactions for CASC22 Gene

SuperPathways for CASC22 Gene

No Data Available

Interacting Proteins for CASC22 Gene

Gene Ontology (GO) - Biological Process for CASC22 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for CASC22 Gene

Drugs & Compounds for CASC22 Gene

No Compound Related Data Available

Transcripts for CASC22 Gene

mRNA/cDNA for CASC22 Gene

(3) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :
(2) RNA Central transcripts :

Alternative Splicing Database (ASD) splice patterns (SP) for CASC22 Gene

No ASD Table

Relevant External Links for CASC22 Gene

GeneLoc Exon Structure for
CASC22
ECgene alternative splicing isoforms for
CASC22

Expression for CASC22 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for CASC22 Gene

NURSA nuclear receptor signaling pathways regulating expression of CASC22 Gene:

CASC22
genes like me logo Genes that share expression patterns with CASC22: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for CASC22 Gene

Orthologs for CASC22 Gene

Evolution for CASC22 Gene

ENSEMBL:
Gene Tree for CASC22 (if available)
TreeFam:
Gene Tree for CASC22 (if available)

No data available for Orthologs for CASC22 Gene

Paralogs for CASC22 Gene

No data available for Paralogs for CASC22 Gene

Variants for CASC22 Gene

Sequence variations from dbSNP and Humsavar for CASC22 Gene

SNP ID Clin Chr 16 pos Variation AA Info Type
rs1000015722 -- 52,263,236(+) T/C intron_variant
rs1000088725 -- 52,262,902(+) T/C intron_variant
rs1000587514 -- 52,258,552(+) G/A upstream_transcript_variant
rs1000866942 -- 52,270,605(+) C/A intron_variant
rs1001016084 -- 52,264,781(+) T/A intron_variant

Additional Variant Information for CASC22 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
CASC22

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for CASC22 Gene

Disorders for CASC22 Gene

MalaCards: The human disease database

(1) MalaCards diseases for CASC22 Gene - From: LncRNADisease and DISEASES

Disorder Aliases PubMed IDs
breast cancer
  • breast cancer, familial
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for CASC22

genes like me logo Genes that share disorders with CASC22: view

No data available for UniProtKB/Swiss-Prot and Genatlas for CASC22 Gene

Publications for CASC22 Gene

  1. A polymorphism rs12325489C>T in the lincRNA-ENST00000515084 exon was found to modulate breast cancer risk via GWAS-based association analyses. (PMID: 24879036) Li N … Zhang C (PloS one 2014) 2 3 58
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 58

Products for CASC22 Gene

Sources for CASC22 Gene

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