Aliases for CASC18 Gene

Subcategory (RNA class) for CASC18 Gene

lncRNA

Number of RNA Genes sources:

4 / 17

Aliases for CASC18 Gene

  • Cancer Susceptibility 18 2 3 5
  • CASC18 2 5 165
  • Cancer Susceptibility Candidate 18 (Non-Protein Coding) 2 3
  • Cancer Susceptibility 18 (Non-Protein Coding) 2 3
  • NONHSAG012162.2 91
  • HSALNG0093715 164
  • LOC101929110 2

External Ids for CASC18 Gene

Previous GeneCards Identifiers for CASC18 Gene

  • GC12P106099

Summaries for CASC18 Gene

GeneCards Summary for CASC18 Gene

CASC18 (Cancer Susceptibility 18) is an RNA Gene, and is affiliated with the lncRNA class.

Additional gene information for CASC18 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for CASC18 Gene

Genomics for CASC18 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for CASC18 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH12J105705 Enhancer 1.3 Ensembl ENCODE CraniofacialAtlas dbSUPER 600.7 +1.7 1745 3.5 CTCF TEAD4 PRDM10 ZNF629 PATZ1 REST RAD21 TRIM22 ZNF341 MNT CASC18 LOC105369959 NUAK1 APPL2
GH12J105409 Enhancer 1.1 ENCODE CraniofacialAtlas dbSUPER 6.8 -294.2 -294156 2 ZNF221 PRDM10 ZNF629 ZNF692 ZNF300 ZIC2 ZNF776 PATZ1 ZNF37A ZNF561 APPL2 CASC18 lnc-C12orf75-1 LOC105369955 LOC105369957 NUAK1
GH12J105352 Enhancer 1 Ensembl ENCODE 5.6 -351.5 -351502 2.2 SP1 PRDM10 POLR2A FOXA1 ZIC2 TCF12 IKZF2 YY1 PKNOX1 EED C12orf75 APPL2 CASC18 LOC105369957 HF679086 NUAK1
GH12J105382 Enhancer 0.8 ENCODE CraniofacialAtlas 4.3 -321.1 -321128 1.1 CTCF REST RAD21 TRIM22 SMC3 ZBTB17 CUX1 ZNF335 ZNF384 ZNF654 C12orf75 APPL2 CASC18 LOC105369957 lnc-APPL2-3 lnc-C12orf75-1 NUAK1
GH12J105368 Enhancer 0.6 Ensembl ENCODE 5.2 -335.7 -335702 1 TEAD4 KDM1A CTCF C12orf75 CASC18 LOC105369957 HF679086 APPL2 NUAK1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around CASC18 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for CASC18 Gene

Genomic Locations for CASC18 Gene
chr12:105,704,203-105,745,475
(GRCh38/hg38)
Size:
41,273 bases
Orientation:
Plus strand
chr12:106,097,981-106,137,840
(GRCh37/hg19)
Size:
39,860 bases
Orientation:
Plus strand

Genomic View for CASC18 Gene

Genes around CASC18 on UCSC Golden Path with GeneCards custom track
CASC18 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
CASC18 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CASC18 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CASC18 Gene

Proteins for CASC18 Gene

Post-translational modifications for CASC18 Gene

No Post-translational modifications

No data available for DME Specific Peptides for CASC18 Gene

Domains & Families for CASC18 Gene

Gene Families for CASC18 Gene

genes like me logo Genes that share domains with CASC18: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for CASC18 Gene

Function for CASC18 Gene

Phenotypes From GWAS Catalog for CASC18 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for CASC18 Gene

Localization for CASC18 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for CASC18 Gene

Pathways & Interactions for CASC18 Gene

PathCards logo

SuperPathways for CASC18 Gene

No Data Available

Gene Ontology (GO) - Biological Process for CASC18 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for CASC18 Gene

Drugs & Compounds for CASC18 Gene

No Compound Related Data Available

Transcripts for CASC18 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for CASC18 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS00004D8A71_9606 lncRNA 2503 4

Ensembl: ENST00000548557 (view in UCSC) ,

LncBook: HSALNT0194357,

LNCipedia: CASC18:1,

NONCODE: NONHSAT030459.2,

URS000018629C_9606 lncRNA 557 4

Ensembl: ENST00000547465 (view in UCSC) ,

LncBook: HSALNT0194361,

LNCipedia: CASC18:4,

NONCODE: NONHSAT030460.2,

URS000055ECA4_9606 lncRNA 2504 3

HGNC: 49463,

RefSeq: NR_110108,

ENA: AB849958.1:1..2521:ncRNA,

URS00008BA7B9_9606 lncRNA 2391 3

RefSeq: NR_110111,

LncBook: HSALNT0194363,

LNCipedia: CASC18:6,

URS0000213ECB_9606 lncRNA 2621 2

RefSeq: NR_110109,

ENA: AB849960.1:1..2638:ncRNA,

CASC18 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Additional transcripts not in RNAcentral for CASC18 Gene

8 NCBI additional mRNA sequence :

Alternative Splicing Database (ASD) splice patterns (SP) for CASC18 Gene

No ASD Table

Relevant External Links for CASC18 Gene

GeneLoc Exon Structure for
CASC18

Expression for CASC18 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for CASC18 Gene

mRNA differential expression in normal tissues according to GTEx for CASC18 Gene

This gene is overexpressed in Artery - Aorta (x7.5), Artery - Coronary (x4.4), and Artery - Tibial (x4.2).

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for CASC18

genes like me logo Genes that share expression patterns with CASC18: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for CASC18 Gene

Orthologs for CASC18 Gene

Evolution for CASC18 Gene

ENSEMBL:
Gene Tree for CASC18 (if available)
TreeFam:
Gene Tree for CASC18 (if available)

No data available for Orthologs for CASC18 Gene

Paralogs for CASC18 Gene

No data available for Paralogs for CASC18 Gene

Variants for CASC18 Gene

Additional dbSNP identifiers (rs#s) for CASC18 Gene

Structural Variations from Database of Genomic Variants (DGV) for CASC18 Gene

Variant ID Type Subtype PubMed ID
dgv1551n100 CNV gain 25217958
nsv1039068 CNV gain 25217958
nsv476086 CNV novel sequence insertion 20440878

Additional Variant Information for CASC18 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
CASC18

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for CASC18 Gene

Disorders for CASC18 Gene

No disorders were found for CASC18 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CASC18 Gene

Publications for CASC18 Gene

  1. Introduction of novel splice variants for CASC18 gene and its relation to the neural differentiation. (PMID: 27956168) Mehravar M … Soltani BM (Gene 2017) 3
  2. APOE and BCHE as modulators of cerebral amyloid deposition: a florbetapir PET genome-wide association study. (PMID: 23419831) Ramanan VK … Alzheimer’s Disease Neuroimaging Initiative (Molecular psychiatry 2014) 3
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3

Products for CASC18 Gene

Sources for CASC18 Gene