Aliases for CASC16 Gene

Subcategory (RNA class) for CASC16 Gene

lncRNA

Number of RNA Genes sources:

3 / 14

Aliases for CASC16 Gene

  • Cancer Susceptibility 16 2 3 5
  • Cancer Susceptibility Candidate 16 (Non-Protein Coding) 2 3
  • Cancer Susceptibility 16 (Non-Protein Coding) 2 3
  • Long Intergenic Non-Protein Coding RNA 918 2 3
  • CASC16 2 168
  • HSALNG0111460 167
  • NONHSAG019462 92
  • LINC00918 3

External Ids for CASC16 Gene

Previous HGNC Symbols for CASC16 Gene

  • LINC00918

Summaries for CASC16 Gene

GeneCards Summary for CASC16 Gene

CASC16 (Cancer Susceptibility 16) is an RNA Gene, and is affiliated with the lncRNA class. Diseases associated with CASC16 include Restless Legs Syndrome.

Additional gene information for CASC16 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for CASC16 Gene

Genomics for CASC16 Gene

GeneHancer (GH) Regulatory Elements for CASC16 Gene

Promoters and enhancers for CASC16 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH16J052597 Enhancer 1 Ensembl ENCODE 6.1 +54.2 54197 0.5 FOXK2 ZNF217 NCOR1 TCF7 FOXA1 ZBTB25 TGIF2 SKI TEAD1 TBX3 CASC16 LOC105371264 ENSG00000285800
GH16J052602 Enhancer 0.4 Ensembl 5.8 +48.8 48831 1 PKNOX1 NFIA PBX2 CASC16 LOC105371264 ENSG00000285800
GH16J052598 Enhancer 0.2 Ensembl 6.1 +53.6 53631 0.2 CASC16 LOC105371264 ENSG00000285800
GH16J052591 Enhancer 0.2 ENCODE 6.1 +60.2 60219 1.3 CASC16 ENSG00000285800 LOC105371264
GH16J052611 Enhancer 1.1 Ensembl ENCODE 0.3 +39.6 39596 2.2 EP300 FOXK2 TCF12 POLR2G NCOR1 KDM6A TCF7 FOXA1 ZBTB25 TGIF2 ENSG00000260393 ENSG00000261261 LOC105371264 CASC16
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around CASC16 on UCSC Golden Path with GeneCards custom track

Genomic Locations for CASC16 Gene

Genomic Locations for CASC16 Gene
chr16:52,552,074-52,652,132
(GRCh38/hg38)
Size:
100,059 bases
Orientation:
Minus strand
chr16:52,585,999-52,686,017
(GRCh37/hg19)
Size:
100,019 bases
Orientation:
Minus strand

Genomic View for CASC16 Gene

Genes around CASC16 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CASC16 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CASC16 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CASC16 Gene

Proteins for CASC16 Gene

Post-translational modifications for CASC16 Gene

No Post-translational modifications

No data available for DME Specific Peptides for CASC16 Gene

Domains & Families for CASC16 Gene

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for CASC16 Gene

Function for CASC16 Gene

Phenotypes From GWAS Catalog for CASC16 Gene

Phenotypes for CASC16 Gene

genes like me logo Genes that share phenotypes with CASC16: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for CASC16 Gene

Localization for CASC16 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for CASC16 Gene

Pathways & Interactions for CASC16 Gene

PathCards logo

SuperPathways for CASC16 Gene

No Data Available
;

Gene Ontology (GO) - Biological Process for CASC16 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for CASC16 Gene

Drugs & Compounds for CASC16 Gene

No Compound Related Data Available

Transcripts for CASC16 Gene

mRNA/cDNA for CASC16 Gene

12 RNACentral transcripts :
1 REFSEQ mRNAs :
4 NCBI additional mRNA sequence :
5 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
7 NONCODE transcripts :
6 LncBook transcripts :
8 LNCipedia transcripts :

Alternative Splicing Database (ASD) splice patterns (SP) for CASC16 Gene

No ASD Table

Relevant External Links for CASC16 Gene

GeneLoc Exon Structure for
CASC16

Expression for CASC16 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for CASC16 Gene

mRNA differential expression in normal tissues according to GTEx for CASC16 Gene

This gene is overexpressed in Testis (x48.8).

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for CASC16

genes like me logo Genes that share expression patterns with CASC16: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for CASC16 Gene

Orthologs for CASC16 Gene

Evolution for CASC16 Gene

ENSEMBL:
Gene Tree for CASC16 (if available)
TreeFam:
Gene Tree for CASC16 (if available)

No data available for Orthologs for CASC16 Gene

Paralogs for CASC16 Gene

No data available for Paralogs for CASC16 Gene

Variants for CASC16 Gene

Additional dbSNP identifiers (rs#s) for CASC16 Gene

Structural Variations from Database of Genomic Variants (DGV) for CASC16 Gene

Variant ID Type Subtype PubMed ID
esv2662247 CNV deletion 23128226
esv3638632 CNV gain 21293372
esv3638633 OTHER inversion 21293372
esv3638634 CNV loss 21293372
nsv1065333 CNV gain 25217958
nsv1066719 CNV loss 25217958
nsv476955 CNV novel sequence insertion 20440878
nsv833230 CNV loss 17160897

Additional Variant Information for CASC16 Gene

Human Gene Mutation Database (HGMD)
CASC16
SNPedia medical, phenotypic, and genealogical associations of SNPs for
CASC16

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for CASC16 Gene

Disorders for CASC16 Gene

MalaCards: The human disease database

(1) MalaCards diseases for CASC16 Gene - From: GeneCards

Disorder Aliases PubMed IDs
restless legs syndrome
  • ekbom syndrome
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for CASC16

genes like me logo Genes that share disorders with CASC16: view

No data available for UniProtKB/Swiss-Prot and Genatlas for CASC16 Gene

Publications for CASC16 Gene

  1. Genome-wide association study of breast cancer in Latinas identifies novel protective variants on 6q25. (PMID: 25327703) Fejerman L … Ziv E (Nature communications 2014) 3 54
  2. Large-scale genotyping identifies 41 new loci associated with breast cancer risk. (PMID: 23535729) Michailidou K … Easton DF (Nature genetics 2013) 3 54
  3. Genome-wide association study of breast cancer in the Japanese population. (PMID: 24143190) Low SK … Katagiri T (PloS one 2013) 3 54
  4. Genome-wide association studies identify four ER negative-specific breast cancer risk loci. (PMID: 23535733) Garcia-Closas M … Kraft P (Nature genetics 2013) 3 54
  5. Genome-wide association study identifies a common variant in RAD51B associated with male breast cancer risk. (PMID: 23001122) Orr N … Swerdlow AJ (Nature genetics 2012) 3 54

Products for CASC16 Gene

Sources for CASC16 Gene