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Aliases for CASC11 Gene

Subcategory (RNA class) for CASC11 Gene

non-coding RNA

Quality Score for this RNA gene is


Aliases for CASC11 Gene

  • Cancer Susceptibility 11 2 3
  • Cancer Susceptibility 11 (Non-Protein Coding) 2 3 5
  • Cancer Susceptibility Candidate 11 (Non-Protein Coding) 2 3
  • Long Intergenic Non-Protein Coding RNA 990 2 3
  • TCONS_00014535 3
  • LINC00990 3
  • CARLo-7 3
  • CARLO7 3

External Ids for CASC11 Gene

Previous GeneCards Identifiers for CASC11 Gene

  • GC08M128699

Summaries for CASC11 Gene

GeneCards Summary for CASC11 Gene

CASC11 (Cancer Susceptibility 11) is an RNA Gene, and is affiliated with the non-coding RNA class. Diseases associated with CASC11 include Colorectal Cancer and Hepatocellular Carcinoma.

Additional gene information for CASC11 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CASC11 Gene

Genomics for CASC11 Gene

GeneHancer (GH) Regulatory Elements for CASC11 Gene

Promoters and enhancers for CASC11 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH08J128171 Enhancer 1.8 FANTOM5 Ensembl ENCODE dbSUPER 10.5 -442.4 -442416 9.3 YBX1 FEZF1 DMAP1 YY1 E2F8 ZNF548 NFYC PPARGC1A MEF2D GLIS1 MIR1208 MIR1207 MYC CASC11 RNU4-25P GC08P128172 GC08P128221
GH08J127758 Enhancer 1.6 FANTOM5 Ensembl ENCODE dbSUPER 11.8 -26.2 -26216 2.8 HDGF PKNOX1 ATF1 ARNT SIN3A BRCA1 NCOA2 ZNF766 ATF7 NCOA1 SRRM1P1 PVT1 MIR1204 MYC CASC11 TMEM75 MIR1207 RNU4-25P GC08P127744
GH08J127806 Enhancer 1.6 FANTOM5 Ensembl ENCODE dbSUPER 11.4 -76.9 -76882 8.6 HDGF PKNOX1 NEUROD1 SIN3A YBX1 ZBTB7B BRCA1 ETS1 GLIS2 E2F8 MYC SRRM1P1 CASC11 TMEM75 MIR1207 RNU1-106P PVT1 MIR1204 ENSG00000278324
GH08J128181 Enhancer 1.7 FANTOM5 Ensembl ENCODE dbSUPER 10.5 -450.1 -450068 5.1 HDGF FOXA2 MLX ZFP64 ARID4B YBX1 DMAP1 ZBTB7B SLC30A9 ZNF766 MYC MIR1208 MIR1207 CASC11 RNU1-106P TMEM75 RNU4-25P GC08P128172 GC08P128221
GH08J127863 Enhancer 1.6 FANTOM5 Ensembl ENCODE dbSUPER 11 -134.4 -134365 10.2 HDGF ATF1 PKNOX1 CLOCK NEUROD1 SIN3A YBX1 ZBTB7B YY1 ETS1 SRRM1P1 RNU1-106P MIR1204 PVT1 CASC11 MYC TMEM75 RNU4-25P ENSG00000278324
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around CASC11 on UCSC Golden Path with GeneCards custom track

Genomic Locations for CASC11 Gene

Genomic Locations for CASC11 Gene
47,625 bases
Minus strand

Genomic View for CASC11 Gene

Genes around CASC11 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CASC11 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CASC11 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CASC11 Gene

Proteins for CASC11 Gene

Post-translational modifications for CASC11 Gene

No Post-translational modifications

No data available for DME Specific Peptides for CASC11 Gene

Domains & Families for CASC11 Gene

Gene Families for CASC11 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CASC11: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for CASC11 Gene

Function for CASC11 Gene

Phenotypes From GWAS Catalog for CASC11 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for CASC11 Gene

Localization for CASC11 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for CASC11 Gene

Pathways & Interactions for CASC11 Gene

SuperPathways for CASC11 Gene

No Data Available

Interacting Proteins for CASC11 Gene

Gene Ontology (GO) - Biological Process for CASC11 Gene


No data available for Pathways by source and SIGNOR curated interactions for CASC11 Gene

Drugs & Compounds for CASC11 Gene

No Compound Related Data Available

Transcripts for CASC11 Gene

mRNA/cDNA for CASC11 Gene

(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :
(3) RNA Central transcripts :

Alternative Splicing Database (ASD) splice patterns (SP) for CASC11 Gene

No ASD Table

Relevant External Links for CASC11 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for CASC11 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for CASC11 Gene

NURSA nuclear receptor signaling pathways regulating expression of CASC11 Gene:

genes like me logo Genes that share expression patterns with CASC11: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for CASC11 Gene

Orthologs for CASC11 Gene

Evolution for CASC11 Gene

Gene Tree for CASC11 (if available)
Gene Tree for CASC11 (if available)

No data available for Orthologs for CASC11 Gene

Paralogs for CASC11 Gene

No data available for Paralogs for CASC11 Gene

Variants for CASC11 Gene

Sequence variations from dbSNP and Humsavar for CASC11 Gene

SNP ID Clin Chr 08 pos Variation AA Info Type
rs1000179953 -- 127,727,991(-) A/T genic_downstream_transcript_variant, intron_variant
rs1000528432 -- 127,721,989(-) A/C genic_downstream_transcript_variant, intron_variant
rs1000582000 -- 127,734,066(-) G/A upstream_transcript_variant
rs1000586224 -- 127,715,954(-) C/A/G genic_downstream_transcript_variant, non_coding_transcript_variant
rs1000777844 -- 127,734,079(-) G/T upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for CASC11 Gene

Variant ID Type Subtype PubMed ID
esv2658660 CNV deletion 23128226
esv2675213 CNV deletion 23128226
esv2752208 CNV gain 17911159
esv3544187 CNV deletion 23714750
esv3618779 CNV loss 21293372
esv3618780 CNV loss 21293372
nsv499795 OTHER inversion 21111241
nsv516713 CNV gain+loss 19592680
nsv7419 OTHER inversion 18451855
nsv831458 CNV loss 17160897

Additional Variant Information for CASC11 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for CASC11 Gene

Disorders for CASC11 Gene

MalaCards: The human disease database

(2) MalaCards diseases for CASC11 Gene - From: LncRNADisease and DISEASES

Disorder Aliases PubMed IDs
colorectal cancer
  • crc
hepatocellular carcinoma
  • hcc
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for CASC11

genes like me logo Genes that share disorders with CASC11: view

No data available for UniProtKB/Swiss-Prot and Genatlas for CASC11 Gene

Publications for CASC11 Gene

  1. Identification of long noncoding RNA expression profile in oxaliplatin-resistant hepatocellular carcinoma cells. (PMID: 27729273) Yin X … Ren ZG (Gene 2017) 2 3 58
  2. Long-range interaction and correlation between MYC enhancer and oncogenic long noncoding RNA CARLo-5. (PMID: 24594601) Kim T … Croce CM (Proceedings of the National Academy of Sciences of the United States of America 2014) 2 3 58
  3. Long non-coding RNA CASC11 interacts with hnRNP-K and activates the WNT/β-catenin pathway to promote growth and metastasis in colorectal cancer. (PMID: 27012187) Zhang Z … Li X (Cancer letters 2016) 3 58
  4. Sequence variant on 8q24 confers susceptibility to urinary bladder cancer. (PMID: 18794855) Kiemeney LA … Stefansson K (Nature genetics 2008) 3 58

Products for CASC11 Gene

Sources for CASC11 Gene

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