Aliases for CARTPT Gene
External Ids for CARTPT Gene
Previous GeneCards Identifiers for CARTPT Gene
This gene encodes a preproprotein that is proteolytically processed to generate multiple biologically active peptides. These peptides play a role in appetite, energy balance, maintenance of body weight, reward and addiction, and the stress response. Expression of a similar gene transcript in rodents is upregulated following administration of cocaine and amphetamine. Mutations in this gene are associated with susceptibility to obesity in humans. [provided by RefSeq, Feb 2016]
GeneCards Summary for CARTPT Gene
CARTPT (CART Prepropeptide) is a Protein Coding gene. Diseases associated with CARTPT include Body Mass Index Quantitative Trait Locus 11 and Relapsed/Refractory Diffuse Large B-Cell Lymphoma. Among its related pathways are Circadian rythm related genes and Glucose / Energy Metabolism.
UniProtKB/Swiss-Prot Summary for CARTPT Gene
Satiety factor closely associated with the actions of leptin and neuropeptide y; this anorectic peptide inhibits both normal and starvation-induced feeding and completely blocks the feeding response induced by neuropeptide Y and regulated by leptin in the hypothalamus. It promotes neuronal development and survival in vitro.