Aliases for CARTPT Gene
External Ids for CARTPT Gene
Previous GeneCards Identifiers for CARTPT Gene
This gene encodes a preproprotein that is proteolytically processed to generate multiple biologically active peptides. These peptides play a role in appetite, energy balance, maintenance of body weight, reward and addiction, and the stress response. Expression of a similar gene transcript in rodents is upregulated following administration of cocaine and amphetamine. Mutations in this gene are associated with susceptibility to obesity in humans. [provided by RefSeq, Feb 2016]
GeneCards Summary for CARTPT Gene
CARTPT (CART Prepropeptide) is a Protein Coding gene. Diseases associated with CARTPT include Body Mass Index Quantitative Trait Locus 11 and Human Immunodeficiency Virus Infectious Disease. Among its related pathways are Circadian rythm related genes and Glucose / Energy Metabolism.
UniProtKB/Swiss-Prot for CARTPT Gene
Satiety factor closely associated with the actions of leptin and neuropeptide y; this anorectic peptide inhibits both normal and starvation-induced feeding and completely blocks the feeding response induced by neuropeptide Y and regulated by leptin in the hypothalamus. It promotes neuronal development and survival in vitro.