Aliases for CARNS1 Gene
External Ids for CARNS1 Gene
Previous HGNC Symbols for CARNS1 Gene
Previous GeneCards Identifiers for CARNS1 Gene
CARNS1 (EC 188.8.131.52), a member of the ATP-grasp family of ATPases, catalyzes the formation of carnosine (beta-alanyl-L-histidine) and homocarnosine (gamma-aminobutyryl-L-histidine), which are found mainly in skeletal muscle and the central nervous system, respectively (Drozak et al., 2010 [PubMed 20097752]).[supplied by OMIM, Apr 2010]
GeneCards Summary for CARNS1 Gene
CARNS1 (Carnosine Synthase 1) is a Protein Coding gene. Among its related pathways are Arginine and proline metabolism and Metabolism. Gene Ontology (GO) annotations related to this gene include ATPase activity and carnosine synthase activity. An important paralog of this gene is HAO2.
UniProtKB/Swiss-Prot Summary for CARNS1 Gene
Catalyzes the synthesis of carnosine and homocarnosine. Carnosine is synthesized more efficiently than homocarnosine.