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Aliases for CARMN Gene

Subcategory (RNA class) for CARMN Gene

non-coding RNA

Quality Score for this RNA gene is

3

Aliases for CARMN Gene

  • Cardiac Mesoderm Enhancer-Associated Non-Coding RNA 2 3 5
  • MIR143 Host Gene (Non-Protein Coding) 2 3
  • Cardiac Mesoderm Enhancer-Associated Noncoding RNA 3
  • MIR143 And MIR145 Host Gene 2
  • MIR143 And MIR145 Host 3
  • MIR143 Host Gene 2
  • MIR143HG 3
  • CARMEN 3

External Ids for CARMN Gene

Previous HGNC Symbols for CARMN Gene

  • MIR143HG

Summaries for CARMN Gene

GeneCards Summary for CARMN Gene

CARMN (Cardiac Mesoderm Enhancer-Associated Non-Coding RNA) is an RNA Gene, and is affiliated with the non-coding RNA class. Diseases associated with CARMN include Hirschsprung Disease 1.

Additional gene information for CARMN Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CARMN Gene

Genomics for CARMN Gene

GeneHancer (GH) Regulatory Elements for CARMN Gene

Promoters and enhancers for CARMN Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH05I149449 Enhancer 1.8 FANTOM5 Ensembl ENCODE dbSUPER 22.5 +46.8 46778 8.5 HDGF PKNOX1 SMAD1 FOXA2 MLX ARNT ZFP64 ARID4B YBX1 DMAP1 HMGXB3 TCOF1 TIGD6 RPL7P1 RPS20P4 CARMN CSNK1A1 PDGFRB RPS14 ARHGEF37
GH05I149956 Promoter/Enhancer 2.8 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 11.8 +553.0 552960 6.7 HDGF PKNOX1 CLOCK SMAD1 FOXA2 MLX ZFP64 ARID4B SIN3A FEZF1 SLC26A2 PDE6A HMGXB3 TCOF1 ZNF300 ZNF300P1 TIGD6 RPL7P1 CSNK1A1 RPS20P4
GH05I149343 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 10 -60.0 -59992 6.4 ZFP64 DMAP1 YY1 ZNF213 E2F8 ZNF143 SP3 PPARGC1A MEF2D ZNF610 GRPEL2 HMGXB3 ENSG00000251330 FBXO38 PCYOX1L RPL7P1 ENSG00000253865 RPS20P4 MIR143 MIR145
GH05I149356 Promoter/Enhancer 2.2 EPDnew FANTOM5 Ensembl ENCODE 9.9 -48.7 -48658 2.6 HDGF PKNOX1 ATF1 SIN3A GLIS2 ELK1 ZNF207 ZNF143 FOS ATF7 PCYOX1L GRPEL2-AS1 GC05P149356 TCOF1 MIR145 MIR143 RNU6-588P IL17B CARMN FBXO38
GH05I149438 Enhancer 1.7 VISTA Ensembl ENCODE dbSUPER 11.4 +36.7 36714 10.2 HDGF PKNOX1 FOXA2 ARNT ARID4B NEUROD1 SIN3A DMAP1 ZBTB7B POLR2B TCOF1 HMGXB3 RPL7P1 TIGD6 PCYOX1L CARMN IL17B RPS20P4 ARHGEF37 PDGFRB
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around CARMN on UCSC Golden Path with GeneCards custom track

Genomic Locations for CARMN Gene

Genomic Locations for CARMN Gene
chr5:149,406,689-149,432,836
(GRCh38/hg38)
Size:
26,148 bases
Orientation:
Plus strand
chr5:148,786,252-148,812,399
(GRCh37/hg19)

Genomic View for CARMN Gene

Genes around CARMN on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CARMN Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CARMN Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CARMN Gene

Proteins for CARMN Gene

Post-translational modifications for CARMN Gene

No Post-translational modifications

No data available for DME Specific Peptides for CARMN Gene

Domains & Families for CARMN Gene

Gene Families for CARMN Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CARMN: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for CARMN Gene

Function for CARMN Gene

Phenotypes From GWAS Catalog for CARMN Gene

Phenotypes for CARMN Gene

GenomeRNAi human phenotypes for CARMN:
genes like me logo Genes that share phenotypes with CARMN: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for CARMN Gene

Localization for CARMN Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for CARMN Gene

Pathways & Interactions for CARMN Gene

SuperPathways for CARMN Gene

No Data Available

Interacting Proteins for CARMN Gene

Gene Ontology (GO) - Biological Process for CARMN Gene

None

No data available for Pathways by source and SIGNOR curated interactions for CARMN Gene

Drugs & Compounds for CARMN Gene

No Compound Related Data Available

Transcripts for CARMN Gene

mRNA/cDNA for CARMN Gene

(12) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for CARMN Gene

No ASD Table

Relevant External Links for CARMN Gene

GeneLoc Exon Structure for
CARMN
ECgene alternative splicing isoforms for
CARMN

Expression for CARMN Gene

NURSA nuclear receptor signaling pathways regulating expression of CARMN Gene:

CARMN
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for CARMN Gene

Orthologs for CARMN Gene

Evolution for CARMN Gene

ENSEMBL:
Gene Tree for CARMN (if available)
TreeFam:
Gene Tree for CARMN (if available)

No data available for Orthologs for CARMN Gene

Paralogs for CARMN Gene

No data available for Paralogs for CARMN Gene

Variants for CARMN Gene

Sequence variations from dbSNP and Humsavar for CARMN Gene

SNP ID Clin Chr 05 pos Variation AA Info Type
rs1000039678 -- 149,412,492(+) G/A intron_variant
rs1000085959 -- 149,411,348(+) T/G intron_variant
rs1000223068 -- 149,425,491(+) C/A intron_variant
rs1000275419 -- 149,425,800(+) T/C intron_variant
rs1000579512 -- 149,415,313(+) G/C intron_variant

Structural Variations from Database of Genomic Variants (DGV) for CARMN Gene

Variant ID Type Subtype PubMed ID
esv2668220 CNV deletion 23128226
nsv516607 CNV loss 19592680
nsv519878 CNV loss 19592680
nsv521406 CNV loss 19592680
nsv528923 CNV loss 19592680
nsv599948 CNV loss 21841781

Additional Variant Information for CARMN Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
CARMN

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for CARMN Gene

Disorders for CARMN Gene

MalaCards: The human disease database

(1) MalaCards diseases for CARMN Gene - From: DISEASES

Disorder Aliases PubMed IDs
hirschsprung disease 1
  • hirschsprung disease, susceptibility to, 1
- elite association - COSMIC cancer census association via MalaCards
Search CARMN in MalaCards View complete list of genes associated with diseases
genes like me logo Genes that share disorders with CARMN: view

No data available for UniProtKB/Swiss-Prot and Genatlas for CARMN Gene

Publications for CARMN Gene

  1. Negative feedback circuitry between MIR143HG and RBM24 in Hirschsprung disease. (PMID: 27565737) Du C … Xia Y (Biochimica et biophysica acta 2016) 2 3 58
  2. CARMEN, a human super enhancer-associated long noncoding RNA controlling cardiac specification, differentiation and homeostasis. (PMID: 26423156) Ounzain S … Pedrazzini T (Journal of molecular and cellular cardiology 2015) 2 3 58
  3. Repression of the miR-143/145 cluster by oncogenic Ras initiates a tumor-promoting feed-forward pathway. (PMID: 21159816) Kent OA … Mendell JT (Genes & development 2010) 3 58
  4. miR-145 participates with TP53 in a death-promoting regulatory loop and targets estrogen receptor-alpha in human breast cancer cells. (PMID: 19730444) Spizzo R … Calin GA (Cell death and differentiation 2010) 3 58
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 58

Products for CARMN Gene

Sources for CARMN Gene

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