Aliases for CARD6 Gene
External Ids for CARD6 Gene
Previous GeneCards Identifiers for CARD6 Gene
This gene encodes a protein that contains a caspase recruitment domain (CARD), an antiparallel six-helical bundle that mediates homotypic protein-protein interactions. The encoded protein is a microtubule-associated protein that has been shown to interact with receptor-interacting protein kinases and positively modulate signal transduction pathways converging on activation of the inducible transcription factor NF-kB. [provided by RefSeq, Jul 2008]
GeneCards Summary for CARD6 Gene
CARD6 (Caspase Recruitment Domain Family Member 6) is a Protein Coding gene. Diseases associated with CARD6 include Glioblastoma Mesenchymal Subtype and Inflammatory Bowel Disease 4. Among its related pathways are Nucleotide-binding Oligomerization Domain (NOD) pathway and NOD-like receptor signaling pathway. An important paralog of this gene is NOL3.
UniProtKB/Swiss-Prot Summary for CARD6 Gene
May be involved in apoptosis.