Aliases for CAPG Gene
External Ids for CAPG Gene
Previous HGNC Symbols for CAPG Gene
Previous GeneCards Identifiers for CAPG Gene
This gene encodes a member of the gelsolin/villin family of actin-regulatory proteins. The encoded protein reversibly blocks the barbed ends of F-actin filaments in a Ca2+ and phosphoinositide-regulated manner, but does not sever preformed actin filaments. By capping the barbed ends of actin filaments, the encoded protein contributes to the control of actin-based motility in non-muscle cells. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jan 2012]
GeneCards Summary for CAPG Gene
CAPG (Capping Actin Protein, Gelsolin Like) is a Protein Coding gene. Diseases associated with CAPG include Fallopian Tube Carcinoma. Gene Ontology (GO) annotations related to this gene include actin binding. An important paralog of this gene is GSN.
UniProtKB/Swiss-Prot Summary for CAPG Gene
Calcium-sensitive protein which reversibly blocks the barbed ends of actin filaments but does not sever preformed actin filaments. May play an important role in macrophage function. May play a role in regulating cytoplasmic and/or nuclear structures through potential interactions with actin. May bind DNA.