This gene encodes a member of the calnexin family of molecular chaperones. The encoded protein is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly f... See more...

Aliases for CANX Gene

Aliases for CANX Gene

  • Calnexin 2 3 4 5
  • Major Histocompatibility Complex Class I Antigen-Binding Protein P88 2 3 4
  • IP90 2 3 4
  • P90 2 3 4
  • CNX 2 3
  • Epididymis Secretory Sperm Binding Protein 3
  • CANX 5

External Ids for CANX Gene

Previous GeneCards Identifiers for CANX Gene

  • GC05P179238
  • GC05P180070
  • GC05P179190
  • GC05P179235
  • GC05P179058
  • GC05P179105
  • GC05P173852

Summaries for CANX Gene

Entrez Gene Summary for CANX Gene

  • This gene encodes a member of the calnexin family of molecular chaperones. The encoded protein is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jun 2018]

GeneCards Summary for CANX Gene

CANX (Calnexin) is a Protein Coding gene. Diseases associated with CANX include Maxillary Sinus Squamous Cell Carcinoma and Anterior Foramen Magnum Meningioma. Among its related pathways are Calnexin/calreticulin cycle and Transport to the Golgi and subsequent modification. Gene Ontology (GO) annotations related to this gene include carbohydrate binding. An important paralog of this gene is CLGN.

UniProtKB/Swiss-Prot Summary for CANX Gene

  • Calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Associated with partial T-cell antigen receptor complexes that escape the ER of immature thymocytes, it may function as a signaling complex regulating thymocyte maturation. Additionally it may play a role in receptor-mediated endocytosis at the synapse.

Gene Wiki entry for CANX Gene

Additional gene information for CANX Gene

No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for CANX Gene

Genomics for CANX Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for CANX Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH05J179696 Promoter/Enhancer 2.4 EPDnew Ensembl ENCODE CraniofacialAtlas dbSUPER 622.5 +20.3 20317 4.9 CEBPG SP1 CREB1 HNRNPL PRDM10 ZNF629 TFE3 RFX1 LEF1 IKZF1 CANX lnc-CBY3-2 lnc-CBY3-4 MAML1 HNRNPH1 ZNF354B MRNIP ZNF354C RUFY1 MGAT4B
GH05J179677 Promoter/Enhancer 1.9 Ensembl ENCODE CraniofacialAtlas 600.7 -0.1 -127 2.6 CEBPG SP1 HNRNPL CREB1 GATAD2A CTCF ZBTB33 ATF7 ZNF629 KDM1A CANX HMGB3P22 NONHSAG042434.2 lnc-CBY3-1 MRNIP ZNF354B MAML1 ZNF879 CNOT6 ZNF354C
GH05J179705 Promoter/Enhancer 0.7 EPDnew dbSUPER 612.6 +27.0 27029 0.1 RBM22 ATF2 CANX HMGB3P22 CBY3 lnc-CBY3-4 RF00017-5173 MAML1
GH05J179816 Promoter/Enhancer 2.4 EPDnew Ensembl ENCODE CraniofacialAtlas dbSUPER 8.2 +141.4 141371 7.6 ARHGAP35 SP1 HNRNPL CREB1 GATAD2A ATF7 PRDM10 ZNF629 TFE3 LEF1 SQSTM1 MRNIP ZNF354C MAML1 HNRNPH1 ZNF879 CNOT6 TBC1D9B RNF130 ENSG00000250999
GH05J179803 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE CraniofacialAtlas dbSUPER 7.9 +127.3 127324 5.9 SP1 HNRNPL GATAD2A PRDM10 ZNF629 ZNF692 RCOR2 POLR2A BACH1 JUND MGAT4B SQSTM1 lnc-MRNIP-4 lnc-LTC4S-2 MRNIP ZNF879 CNOT6 MAML1 HNRNPH1 ENSG00000245317
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around CANX on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for CANX

Top Transcription factor binding sites by QIAGEN in the CANX gene promoter:
  • AP-1
  • ATF-2
  • c-Jun
  • CREB
  • deltaCREB

Genomic Locations for CANX Gene

Genomic Locations for CANX Gene
chr5:179,678,628-179,731,641
(GRCh38/hg38)
Size:
53,014 bases
Orientation:
Plus strand
chr5:179,105,629-179,158,642
(GRCh37/hg19)
Size:
53,014 bases
Orientation:
Plus strand

Genomic View for CANX Gene

Genes around CANX on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CANX Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CANX Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CANX Gene

Proteins for CANX Gene

  • Protein details for CANX Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P27824-CALX_HUMAN
    Recommended name:
    Calnexin
    Protein Accession:
    P27824
    Secondary Accessions:
    • B2R5V8
    • B4DGP8
    • B4E2T8
    • D3DWQ3
    • D6R9K3

    Protein attributes for CANX Gene

    Size:
    592 amino acids
    Molecular mass:
    67568 Da
    Quaternary structure:
    • Interacts with MAPK3/ERK1 (By similarity). Interacts with KCNH2 (PubMed:16361248). Associates with ribosomes (By similarity). Interacts with SGIP1; involved in negative regulation of endocytosis (By similarity). The palmitoylated form interacts with the ribosome-translocon complex component SSR1, promoting efficient folding of glycoproteins (PubMed:22314232). Interacts with SERPINA2P/SERPINA2 and with the S and Z variants of SERPINA1 (PubMed:23826168). Interacts with PPIB (PubMed:20801878). Interacts with ZNRF4 (PubMed:21205830). Interacts with SMIM22 (PubMed:29765154).
    • (Microbial infection) Interacts with HBV large envelope protein, isoform L.
    • (Microbial infection) Interacts with HBV large envelope protein, isoform M; this association may be essential for isoform M proper secretion.

    Alternative splice isoforms for CANX Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for CANX Gene

Post-translational modifications for CANX Gene

  • Phosphorylated at Ser-564 by MAPK3/ERK1. phosphorylation by MAPK3/ERK1 increases its association with ribosomes (By similarity).
  • Palmitoylation by DHHC6 leads to the preferential localization to the perinuclear rough ER. It mediates the association of calnexin with the ribosome-translocon complex (RTC) which is required for efficient folding of glycosylated proteins.
  • Ubiquitinated, leading to proteasomal degradation. Probably ubiquitinated by ZNRF4.
  • Glycosylation at Thr59, Thr66, and Thr79
  • Ubiquitination at Lys118, Lys137, Lys170, Lys182, Lys103, Lys227, Lys398, Lys401, and Lys515
  • Modification sites at PhosphoSitePlus

Antibody Products

Protein Products

No data available for DME Specific Peptides for CANX Gene

Domains & Families for CANX Gene

Gene Families for CANX Gene

Human Protein Atlas (HPA):
  • Cancer-related genes
  • Plasma proteins
  • Predicted intracellular proteins
  • Predicted membrane proteins

Protein Domains for CANX Gene

Suggested Antigen Peptide Sequences for CANX Gene

GenScript: Design optimal peptide antigens:
  • cDNA FLJ54242, highly similar to Calnexin (B4E2T8_HUMAN)
  • p90 (CALX_HUMAN)

Graphical View of Domain Structure for InterPro Entry

P27824

UniProtKB/Swiss-Prot:

CALX_HUMAN :
  • Belongs to the calreticulin family.
Family:
  • Belongs to the calreticulin family.
genes like me logo Genes that share domains with CANX: view

Function for CANX Gene

Molecular function for CANX Gene

UniProtKB/Swiss-Prot Function:
Calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Associated with partial T-cell antigen receptor complexes that escape the ER of immature thymocytes, it may function as a signaling complex regulating thymocyte maturation. Additionally it may play a role in receptor-mediated endocytosis at the synapse.
GENATLAS Biochemistry:
calnexin,90kDa,integral membrane,calcium binding protein,chaperone,interacting with an ER-located peptide transporter for peptide translocation into microsomes

Phenotypes From GWAS Catalog for CANX Gene

Gene Ontology (GO) - Molecular Function for CANX Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003723 RNA binding HDA 22658674
GO:0005509 calcium ion binding IEA,IBA 21873635
GO:0005515 protein binding IEA,IPI 16361248
GO:0030246 carbohydrate binding IEA --
GO:0034185 apolipoprotein binding IEA --
genes like me logo Genes that share ontologies with CANX: view
genes like me logo Genes that share phenotypes with CANX: view

Animal Models for CANX Gene

MGI Knock Outs for CANX:

Animal Model Products

CRISPR Products

miRNA for CANX Gene

miRTarBase miRNAs that target CANX

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for CANX

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for CANX Gene

Localization for CANX Gene

Subcellular locations from UniProtKB/Swiss-Prot for CANX Gene

Endoplasmic reticulum membrane. Single-pass type I membrane protein. Endoplasmic reticulum. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:12643545, PubMed:17081065). The palmitoylated form preferentially localizes to the perinuclear rough ER (PubMed:22314232). {ECO:0000269 PubMed:12643545, ECO:0000269 PubMed:17081065, ECO:0000269 PubMed:22314232}.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for CANX gene
Compartment Confidence
extracellular 5
endoplasmic reticulum 5
plasma membrane 4
cytoskeleton 3
mitochondrion 3
nucleus 3
endosome 3
cytosol 3
lysosome 3
golgi apparatus 3
peroxisome 2

Subcellular locations from the

Human Protein Atlas (HPA)
  • Endoplasmic reticulum (4)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for CANX Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005737 cytoplasm IEA --
GO:0005783 endoplasmic reticulum IEA,IDA 14966132
GO:0005788 endoplasmic reticulum lumen TAS --
GO:0005789 endoplasmic reticulum membrane IDA 19723497
GO:0005790 smooth endoplasmic reticulum IEA --
genes like me logo Genes that share ontologies with CANX: view

Pathways & Interactions for CANX Gene

genes like me logo Genes that share pathways with CANX: view

Pathways by source for CANX Gene

2 GeneGo (Thomson Reuters) pathways for CANX Gene
  • CFTR folding and maturation (norm and CF)
  • Immune response Antigen presentation by MHC class I
1 Cell Signaling Technology pathway for CANX Gene

Gene Ontology (GO) - Biological Process for CANX Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0002474 antigen processing and presentation of peptide antigen via MHC class I TAS --
GO:0006457 protein folding IEA,TAS --
GO:0007568 aging IEA --
GO:0009306 protein secretion TAS 8055875
GO:0016032 viral process IEA --
genes like me logo Genes that share ontologies with CANX: view

No data available for SIGNOR curated interactions for CANX Gene

Drugs & Compounds for CANX Gene

(27) Drugs for CANX Gene - From: DrugBank, HMDB, and Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Antihemophilic factor, human recombinant Approved, Investigational Pharma Target, chaperone 0
Calcium citrate Approved, Investigational Pharma Target, ligand 0
Calcium Phosphate Approved Pharma Target, ligand 0
Calcium phosphate dihydrate Approved Pharma Target 0
Lonoctocog alfa Approved, Investigational Pharma Target, chaperone 0

(17) Additional Compounds for CANX Gene - From: Novoseek

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
genes like me logo Genes that share compounds with CANX: view

Transcripts for CANX Gene

mRNA/cDNA for CANX Gene

11 REFSEQ mRNAs :
16 NCBI additional mRNA sequence :
19 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for CANX

Alternative Splicing Database (ASD) splice patterns (SP) for CANX Gene

ExUns: 1a · 1b · 1c · 1d · 1e ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b · 6c ^ 7 ^ 8 ^ 9a · 9b · 9c ^ 10 ^ 11 ^ 12 ^ 13a · 13b ^ 14 ^ 15a · 15b ^ 16 ^
SP1: - - - - -
SP2: - - - - - - - - - -
SP3:
SP4: - - - - - - - -
SP5: - - -
SP6:
SP7: - - -
SP8: -

ExUns: 17 ^ 18a · 18b ^ 19 ^ 20
SP1:
SP2:
SP3:
SP4:
SP5:
SP6:
SP7:
SP8:

Relevant External Links for CANX Gene

GeneLoc Exon Structure for
CANX

Expression for CANX Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for CANX Gene

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for CANX Gene



Protein tissue co-expression partners for CANX Gene

- Elite partner

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for CANX

SOURCE GeneReport for Unigene cluster for CANX Gene:

Hs.567968

Evidence on tissue expression from TISSUES for CANX Gene

  • Nervous system(5)
  • Liver(4.9)
  • Skin(4.9)
  • Blood(4.7)
  • Lung(4.4)
  • Kidney(4.3)
  • Intestine(4.3)
  • Pancreas(3.9)
  • Heart(3.8)
  • Stomach(3.8)
  • Eye(3.7)
  • Spleen(3.5)
  • Muscle(3.5)
  • Thyroid gland(3.3)
  • Bone(3.2)
  • Lymph node(3.1)
  • Adrenal gland(3.1)
  • Bone marrow(3.1)
  • Gall bladder(2.6)
genes like me logo Genes that share expression patterns with CANX: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for CANX Gene

Orthologs for CANX Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for CANX Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia CANX 30 31
  • 99.38 (n)
OneToOne
Dog
(Canis familiaris)
Mammalia CANX 30 31
  • 91.6 (n)
OneToOne
Cow
(Bos Taurus)
Mammalia CANX 30 31
  • 90.69 (n)
OneToOne
Rat
(Rattus norvegicus)
Mammalia Canx 30
  • 89.47 (n)
Mouse
(Mus musculus)
Mammalia Canx 30 17 31
  • 88.31 (n)
OneToOne
Oppossum
(Monodelphis domestica)
Mammalia -- 31
  • 87 (a)
OneToMany
-- 31
  • 82 (a)
OneToMany
-- 31
  • 79 (a)
OneToMany
-- 31
  • 72 (a)
OneToMany
Platypus
(Ornithorhynchus anatinus)
Mammalia CANX 31
  • 86 (a)
OneToOne
Chicken
(Gallus gallus)
Aves CANX 30 31
  • 79.44 (n)
OneToOne
Lizard
(Anolis carolinensis)
Reptilia CANX 31
  • 80 (a)
OneToOne
Tropical Clawed Frog
(Silurana tropicalis)
Amphibia canx 30
  • 73.42 (n)
Zebrafish
(Danio rerio)
Actinopterygii canx 30 31
  • 69.78 (n)
OneToOne
wufc27b06 30
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP005032 30
  • 57.81 (n)
Fruit Fly
(Drosophila melanogaster)
Insecta Cnx14D 30 31
  • 57.23 (n)
ManyToMany
CG9906 32
  • 47 (a)
Cnx99A 31 32
  • 44 (a)
ManyToMany
CG1924 31 32
  • 44 (a)
ManyToMany
Worm
(Caenorhabditis elegans)
Secernentea cnx-1 30 31 32
  • 55.9 (n)
OneToMany
Baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes CNE1 31 33
  • 29 (a)
OneToMany
Thale Cress
(Arabidopsis thaliana)
eudicotyledons CNX1 30
  • 58.25 (n)
Alicante grape
(Vitis vinifera)
eudicotyledons Vvi.2586 30
Soybean
(Glycine max)
eudicotyledons Gma.6427 30
Rice
(Oryza sativa)
Liliopsida Os04g0402100 30
  • 57.68 (n)
Os.11092 30
Barley
(Hordeum vulgare)
Liliopsida Hv.3581 30
Wheat
(Triticum aestivum)
Liliopsida Ta.2538 30
Corn
(Zea mays)
Liliopsida Zm.2862 30
Sea Squirt
(Ciona savignyi)
Ascidiacea -- 31
  • 60 (a)
OneToMany
Sea Vase
(Ciona intestinalis)
Ascidiacea Cin.14852 30
Species where no ortholog for CANX was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)

Evolution for CANX Gene

ENSEMBL:
Gene Tree for CANX (if available)
TreeFam:
Gene Tree for CANX (if available)
Aminode:
Evolutionary constrained regions (ECRs) for CANX: view image

Paralogs for CANX Gene

Paralogs for CANX Gene

(1) SIMAP similar genes for CANX Gene using alignment to 15 proteins:

  • CALX_HUMAN
  • B4DGP8_HUMAN
  • B4E2T8_HUMAN
  • D6RAQ8_HUMAN
  • D6RAU8_HUMAN
  • D6RB85_HUMAN
  • D6RD16_HUMAN
  • D6RDP7_HUMAN
  • D6RFL1_HUMAN
  • D6RFW4_HUMAN
  • D6RG29_HUMAN
  • D6RGY2_HUMAN
  • D6RHJ3_HUMAN
  • H0Y9H1_HUMAN
  • H0Y9Q7_HUMAN
genes like me logo Genes that share paralogs with CANX: view

Variants for CANX Gene

Additional dbSNP identifiers (rs#s) for CANX Gene

Structural Variations from Database of Genomic Variants (DGV) for CANX Gene

Variant ID Type Subtype PubMed ID
nsv5160 CNV insertion 18451855
nsv830560 CNV loss 17160897

Variation tolerance for CANX Gene

Residual Variation Intolerance Score: 18.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.79; 47.44% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for CANX Gene

Human Gene Mutation Database (HGMD)
CANX
SNPedia medical, phenotypic, and genealogical associations of SNPs for
CANX

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for CANX Gene

Disorders for CANX Gene

MalaCards: The human disease database

(24) MalaCards diseases for CANX Gene - From: DISEASES, Novoseek, and GeneCards

Disorder Aliases PubMed IDs
maxillary sinus squamous cell carcinoma
  • epidermoid carcinoma of the maxillofacial sinus
anterior foramen magnum meningioma
  • meningioma of the anterior foramen magnum
influenza
  • flu
glossopharyngeal neuralgia
  • glossopharyngeal nerve diseases
myeloperoxidase deficiency
  • mpod
- elite association - COSMIC cancer census association via MalaCards
Search CANX in MalaCards View complete list of genes associated with diseases

Additional Disease Information for CANX

genes like me logo Genes that share disorders with CANX: view

No data available for UniProtKB/Swiss-Prot and Genatlas for CANX Gene

Publications for CANX Gene

  1. Human, mouse, and rat calnexin cDNA cloning: identification of potential calcium binding motifs and gene localization to human chromosome 5. (PMID: 8136357) Tjoelker LW … Gray PW (Biochemistry 1994) 2 3 4 23
  2. The major histocompatibility complex class I antigen-binding protein p88 is the product of the calnexin gene. (PMID: 1326756) Galvin K … Ozturk M (Proceedings of the National Academy of Sciences of the United States of America 1992) 2 3 4 23
  3. The molecular chaperones HSP28, GRP78, endoplasmin, and calnexin exhibit strikingly different levels in quiescent keratinocytes as compared to their proliferating normal and transformed counterparts: cDNA cloning and expression of calnexin. (PMID: 8055875) Honoré B … Celis JE (Electrophoresis 1994) 3 4 23
  4. The cancer-associated microprotein CASIMO1 controls cell proliferation and interacts with squalene epoxidase modulating lipid droplet formation. (PMID: 29765154) Polycarpou-Schwarz M … Diederichs S (Oncogene 2018) 3 4
  5. SERPINA2 is a novel gene with a divergent function from SERPINA1. (PMID: 23826168) Marques PI … Seixas S (PloS one 2013) 3 4

Products for CANX Gene

  • Addgene plasmids for CANX

Sources for CANX Gene