Aliases for CADM3 Gene
External Ids for CADM3 Gene
Previous HGNC Symbols for CADM3 Gene
Previous GeneCards Identifiers for CADM3 Gene
The protein encoded by this gene is a calcium-independent cell-cell adhesion protein that can form homodimers or heterodimers with other nectin proteins. The encoded protein has both homophilic and heterophilic cell-cell adhesion activity. This gene is reported to be a tumor suppressor gene. [provided by RefSeq, Oct 2016]
GeneCards Summary for CADM3 Gene
CADM3 (Cell Adhesion Molecule 3) is a Protein Coding gene. Diseases associated with CADM3 include Cleft Lip/Palate-Ectodermal Dysplasia Syndrome. Among its related pathways are Cell junction organization and Cell adhesion molecules (CAMs). Gene Ontology (GO) annotations related to this gene include protein homodimerization activity. An important paralog of this gene is CADM2.
UniProtKB/Swiss-Prot Summary for CADM3 Gene
Involved in the cell-cell adhesion. Has both calcium-independent homophilic cell-cell adhesion activity and calcium-independent heterophilic cell-cell adhesion activity with IGSF4, NECTIN1 and NECTIN3. Interaction with EPB41L1 may regulate structure or function of cell-cell junctions (By similarity).