Aliases for CACTIN Gene
External Ids for CACTIN Gene
Previous HGNC Symbols for CACTIN Gene
GeneCards Summary for CACTIN Gene
CACTIN (Cactin, Spliceosome C Complex Subunit) is a Protein Coding gene. Diseases associated with CACTIN include Gluten Allergy and Schopf-Schulz-Passarge Syndrome. An important paralog of this gene is MARVELD3.
UniProtKB/Swiss-Prot Summary for CACTIN Gene
Involved in the regulation of innate immune response (PubMed:20829348). Acts as negative regulator of Toll-like receptor, interferon-regulatory factor (IRF) and canonical NF-kappa-B signaling pathways (PubMed:20829348, PubMed:26363554). Contributes to the regulation of transcriptional activation of NF-kappa-B target genes in response to endogenous proinflammatory stimuli (PubMed:20829348, PubMed:26363554).