Aliases for CACNA1C-AS1 Gene

Subcategory (RNA class) for CACNA1C-AS1 Gene

lncRNA

Number of RNA Genes sources:

3 / 14

Aliases for CACNA1C-AS1 Gene

  • CACNA1C Antisense RNA 1 2 3 5
  • CACNA1C Antisense RNA 1 (Non-Protein Coding) 2 3
  • CACNA1C-AS1 2 168
  • HSALNG0088599 167
  • NONHSAG010194 92

External Ids for CACNA1C-AS1 Gene

Additional External Ids for CACNA1C-AS1 Gene

Previous GeneCards Identifiers for CACNA1C-AS1 Gene

  • GC00U933925
  • GC12M002786

Summaries for CACNA1C-AS1 Gene

GeneCards Summary for CACNA1C-AS1 Gene

CACNA1C-AS1 (CACNA1C Antisense RNA 1) is an RNA Gene, and is affiliated with the lncRNA class. Diseases associated with CACNA1C-AS1 include Brugada Syndrome 3 and Timothy Syndrome.

Additional gene information for CACNA1C-AS1 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for CACNA1C-AS1 Gene

Genomics for CACNA1C-AS1 Gene

GeneHancer (GH) Regulatory Elements for CACNA1C-AS1 Gene

Promoters and enhancers for CACNA1C-AS1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH12J002690 Promoter/Enhancer 1.3 Ensembl ENCODE CraniofacialAtlas 505.8 0.0 0 3.2 CTCF HDAC2 POLR2A YY1 PHF8 ETS1 E2F6 ZNF335 MYC SCRT1 CACNA1C-AS1 ITFG2 FKBP4 piR-32214-101 CACNA1C
GH12J003161 Enhancer 1.3 Ensembl ENCODE CraniofacialAtlas dbSUPER 5.7 -472.8 -472800 4.4 EP300 USF1 NCOR1 TEAD1 ZBTB26 RBM25 KLF9 RAD21 SAP130 CREM TSPAN9 CACNA1C-AS1 ENSG00000275850 TSPAN9-IT1
GH12J003519 Enhancer 0.5 Ensembl 4.4 -828.6 -828600 1.2 ZIC2 NFIC ZBTB48 ZNF335 NFIB GLIS1 ZNF561 ENSG00000243507 ENSG00000256691 ENSG00000255669 CACNA1C-AS1 hsa-miR-5095-083 HSALNG0088663 PRMT8
GH12J003473 Enhancer 0.3 Ensembl 5.1 -783.6 -783600 3.2 KLF1 piR-31343 piR-36777 piR-36935 piR-33604 piR-37684 piR-43470 piR-43481 piR-43491 piR-38114 piR-43717
GH12J002684 Enhancer 0.7 Ensembl ENCODE 0.4 +7.8 7801 3.2 CTCF ZIC2 RAD21 SMC3 ZNF654 CHD4 KLF1 ITFG2 FKBP4 CBX3P4 ENSG00000227081 piR-32214-101 CACNA1C-AS1 CACNA1C-AS2 CACNA1C
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around CACNA1C-AS1 on UCSC Golden Path with GeneCards custom track

Genomic Locations for CACNA1C-AS1 Gene

Genomic Locations for CACNA1C-AS1 Gene
chr12:2,676,001-2,691,201
(GRCh38/hg38)
Size:
15,201 bases
Orientation:
Minus strand
chr12:2,785,167-2,800,366
(GRCh37/hg19)
Size:
15,200 bases
Orientation:
Minus strand

Genomic View for CACNA1C-AS1 Gene

Genes around CACNA1C-AS1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CACNA1C-AS1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CACNA1C-AS1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CACNA1C-AS1 Gene

Proteins for CACNA1C-AS1 Gene

Post-translational modifications for CACNA1C-AS1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for CACNA1C-AS1 Gene

Domains & Families for CACNA1C-AS1 Gene

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for CACNA1C-AS1 Gene

Function for CACNA1C-AS1 Gene

Phenotypes From GWAS Catalog for CACNA1C-AS1 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for CACNA1C-AS1 Gene

Localization for CACNA1C-AS1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for CACNA1C-AS1 Gene

Pathways & Interactions for CACNA1C-AS1 Gene

PathCards logo

SuperPathways for CACNA1C-AS1 Gene

No Data Available
;

Gene Ontology (GO) - Biological Process for CACNA1C-AS1 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for CACNA1C-AS1 Gene

Drugs & Compounds for CACNA1C-AS1 Gene

No Compound Related Data Available

Transcripts for CACNA1C-AS1 Gene

mRNA/cDNA for CACNA1C-AS1 Gene

5 RNACentral transcripts :
1 REFSEQ mRNAs :
2 NCBI additional mRNA sequence :
6 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
4 NONCODE transcripts :
3 LncBook transcripts :
4 LNCipedia transcripts :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for CACNA1C-AS1 Gene

No ASD Table

Relevant External Links for CACNA1C-AS1 Gene

GeneLoc Exon Structure for
CACNA1C-AS1

Expression for CACNA1C-AS1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for CACNA1C-AS1 Gene

mRNA differential expression in normal tissues according to GTEx for CACNA1C-AS1 Gene

This gene is overexpressed in Colon - Sigmoid (x5.2) and Heart - Left Ventricle (x4.1).

SOURCE GeneReport for Unigene cluster for CACNA1C-AS1 Gene:

Hs.683896
genes like me logo Genes that share expression patterns with CACNA1C-AS1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for CACNA1C-AS1 Gene

Orthologs for CACNA1C-AS1 Gene

Evolution for CACNA1C-AS1 Gene

ENSEMBL:
Gene Tree for CACNA1C-AS1 (if available)
TreeFam:
Gene Tree for CACNA1C-AS1 (if available)

No data available for Orthologs for CACNA1C-AS1 Gene

Paralogs for CACNA1C-AS1 Gene

No data available for Paralogs for CACNA1C-AS1 Gene

Variants for CACNA1C-AS1 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for CACNA1C-AS1 Gene

SNP ID Clinical significance and condition Chr 12 pos Variation AA Info Type
638926 Uncertain Significance: Long QT syndrome 2,686,226(-) T/G MISSENSE_VARIANT
644450 Uncertain Significance: Long QT syndrome 2,679,759(-) C/T MISSENSE_VARIANT
645176 Uncertain Significance: Long QT syndrome 2,690,901(-) T/G MISSENSE_VARIANT,NON_CODING_TRANSCRIPT_VARIANT
646004 Uncertain Significance: Long QT syndrome 2,679,750(-) C/T MISSENSE_VARIANT
646740 Uncertain Significance: Long QT syndrome 2,688,784(-) G/C INTRON_VARIANT

Additional dbSNP identifiers (rs#s) for CACNA1C-AS1 Gene

Structural Variations from Database of Genomic Variants (DGV) for CACNA1C-AS1 Gene

Variant ID Type Subtype PubMed ID
dgv1344n100 CNV gain 25217958
dgv244e214 CNV gain 21293372
esv2745416 CNV deletion 23290073
esv3367314 CNV duplication 20981092
nsv1047874 CNV gain 25217958
nsv832308 CNV loss 17160897
nsv983264 CNV duplication 23825009

Additional Variant Information for CACNA1C-AS1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
CACNA1C-AS1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for CACNA1C-AS1 Gene

Disorders for CACNA1C-AS1 Gene

MalaCards: The human disease database

(8) MalaCards diseases for CACNA1C-AS1 Gene - From: GeneCards

Disorder Aliases PubMed IDs
brugada syndrome 3
  • brgda3
timothy syndrome
  • ts
cardiac arrhythmia
  • extrasystoles
short qt syndrome
  • sqts
catecholaminergic polymorphic ventricular tachycardia
  • ventricular tachycardia, catecholaminergic polymorphic, 1
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for CACNA1C-AS1

genes like me logo Genes that share disorders with CACNA1C-AS1: view

No data available for UniProtKB/Swiss-Prot and Genatlas for CACNA1C-AS1 Gene

Publications for CACNA1C-AS1 Gene

  1. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K … Sugano S (Genome research 2006) 3 54
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 54

Products for CACNA1C-AS1 Gene

Sources for CACNA1C-AS1 Gene