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Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue di... See more...
Aliases for CA5B Gene
Aliases for CA5B Gene
External Ids for CA5B Gene
- HGNC: 1378
- Entrez Gene: 11238
- Ensembl: ENSG00000169239
- OMIM: 300230
- UniProtKB: Q9Y2D0
Previous GeneCards Identifiers for CA5B Gene
- GC0XP015466
- GC0XP014582
- GC0XP014941
- GC0XP015117
- GC0XP015516
- GC0XP015666
- GC0XP015706
Summaries for CA5B Gene
-
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. This gene encodes carbonic anhydrase 5B. CA5B, and the related CA5A gene, has its expression localized in the mitochondria though CA5B has a wider tissue distribution than CA5A, which is restricted to the liver, kidneys, and skeletal muscle. A carbonic anhydrase pseudogene (CA5BP1) is adjacent to the CA5B gene and these two loci produce CA5BP1-CA5B readthrough transcripts. [provided by RefSeq, Jan 2019]
GeneCards Summary for CA5B Gene
CA5B (Carbonic Anhydrase 5B) is a Protein Coding gene. Diseases associated with CA5B include Second-Degree Atrioventricular Block and Mobitz Type Ii Atrioventricular Block. Among its related pathways are Metabolism and Nitrogen metabolism. Gene Ontology (GO) annotations related to this gene include carbonate dehydratase activity. An important paralog of this gene is CA5A.
UniProtKB/Swiss-Prot Summary for CA5B Gene
-
Reversible hydration of carbon dioxide.
Additional gene information for CA5B Gene
- HGNC(1378)
- Entrez Gene(11238)
- Ensembl(ENSG00000169239)
- OMIM(300230)
- UniProtKB(Q9Y2D0)
- Open Targets Platform(ENSG00000169239)
- Search for CA5B at DataMed
- Search for CA5B at HumanCyc
No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for CA5B Gene
Genomics for CA5B Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for CA5B Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around CA5B on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for CA5B
- Top Transcription factor binding sites by QIAGEN in the CA5B gene promoter:
-
- AML1a
- FAC1
- FOXJ2
- FOXJ2 (long isoform)
- p53
- Pax-4a
- POU2F1
- POU2F1a
- RP58
Genomic Locations for CA5B Gene
Genomic Locations for CA5B Gene
- chrX:15,688,830-15,788,411
- (GRCh38/hg38)
- Size:
- 99,582 bases
- Orientation:
- Plus strand
- chrX:15,706,953-15,805,748
- (GRCh37/hg19)
- Size:
- 98,796 bases
- Orientation:
- Plus strand
Genomic View for CA5B Gene
Genes around CA5B on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- Xp22.2 by HGNC
- Xp22.2 by Entrez Gene
- Xp22.2 by Ensembl
CA5B Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for CA5B Gene
Proteins for CA5B Gene
-
Protein details for CA5B Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9Y2D0-CAH5B_HUMAN
- Recommended name:
- Carbonic anhydrase 5B, mitochondrial
- Protein Accession:
- Q9Y2D0
- A8K4T5
Protein attributes for CA5B Gene
- Size:
- 317 amino acids
- Molecular mass:
- 36434 Da
- Cofactor:
- Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
- Quaternary structure:
- No Data Available
Protein Expression for CA5B Gene
Selected DME Specific Peptides for CA5B Gene
- Q9Y2D0:
-
- AELHLVH
- GSLTTPPL
- ELHLVHWN
- QFHFHWG
Post-translational modifications for CA5B Gene
Other Protein References for CA5B Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- G Biosciences Immunotag™ CA5B Antibody
-
Custom Antibody ServicesOriGene Antibodies for CA5B
- Novus Biologicals Antibodies for CA5B
- Invitrogen Antibodies for CA5B (AFLGC-CA5B)
-
Santa Cruz Biotechnology (SCBT) Antibodies for CA5B
- Sino Biological Antibodies for CA5B
Protein Products
- G Biosciences Human Carbonic Anhydrase VB/CA5B, Liquid
- Search Origene for MassSpec and Protein Over-expression Lysates for CA5B
- Origene Custom Protein Services for CA5B
- Sino Biological Recombinant Proteins for CA5B
- Browse Sino Biological Cell Lysates
-
Signalway Proteins for CA5B
-
ProSci Proteins for CA5B
-
Abcam proteins for CA5B
Assay Products
- RayBiotech Custom Human CA5B ELISA
- Novus Biologicals ELISA Kits for CA5B
- antibodies-online: Show 22 available CA5B Elisa Kits ranked by validation data
- Compare Top CA5B Elisa Kits
-
Quality Products:
-
Signalway ELISA kits for CA5B
Domains & Families for CA5B Gene
Gene Families for CA5B Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Enzymes
- Predicted intracellular proteins
Protein Domains for CA5B Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for CA5B Gene
- GenScript: Design optimal peptide antigens:
-
- Carbonic anhydrase VB (CAH5B_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q9Y2D0- Family:
-
- Belongs to the alpha-carbonic anhydrase family.
Function for CA5B Gene
Molecular function for CA5B Gene
- UniProtKB/Swiss-Prot Function:
- Reversible hydration of carbon dioxide.
- UniProtKB/Swiss-Prot CatalyticActivity:
- Reaction=H(+) + hydrogencarbonate = CO2 + H2O; Xref=Rhea:RHEA:10748, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:16526, ChEBI:CHEBI:17544; EC=4.2.1.1;.
- UniProtKB/Swiss-Prot EnzymeRegulation:
- Inhibited by coumarins, sulfonamide derivatives such as acetazolamide (AZA), saccharin and Foscarnet (phosphonoformate trisodium salt).
- GENATLAS Biochemistry:
- carbonic anhydrase VB,mitochondrial,expressed in heart,skeletal muscle,pancreas,kidney,salivary glands,spinal cord but not in liver
Enzyme Numbers (IUBMB) for CA5B Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0004089 | carbonate dehydratase activity | TAS,IBA | 21873635 |
| GO:0008270 | zinc ion binding | IEA | -- |
| GO:0016829 | lyase activity | IEA | -- |
| GO:0016836 | hydro-lyase activity | IBA | 21873635 |
| GO:0046872 | metal ion binding | IEA | -- |
Phenotypes for CA5B Gene
- MGI mutant phenotypes for CA5B:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for CA5B:
-
- no effect
- Decreased vaccinia virus (VACV) infection
- Decreased viability ratio
- Increased gamma-H2AX phosphorylation
- Negative genetic interaction between KRASG13D/+ and KRAS+/-
- Decreased human papilloma virus 16 (HPV16) pseudovirus infection
- Increased NF-kappaB reporter expression
- Increased shRNA abundance (Z-score > 2)
- Decreased shRNA abundance (Z-score < -2)
- Lamellipodia cells
Animal Models for CA5B Gene
- MGI Knock Outs for CA5B:
-
- Car5b Car5b<tm1Sly>
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for CA5B - Select products 50% OFF >
- * CA5B CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for CA5B
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for CA5B
-
Santa Cruz Biotechnology (SCBT) CRISPR for CA5B
miRNA for CA5B Gene
- miRTarBase miRNAs that target CA5B
-
- hsa-miR-335-5p (MIRT018795)
- hsa-miR-142-3p (MIRT021623)
- hsa-miR-124-3p (MIRT023038)
- hsa-miR-92a-3p (MIRT049682)
- hsa-let-7e-5p (MIRT051681)
- hsa-miR-4662a-5p (MIRT442939)
- hsa-miR-7703 (MIRT680737)
- hsa-miR-6720-5p (MIRT680738)
- hsa-miR-6512-3p (MIRT680739)
- hsa-miR-542-3p (MIRT680740)
- hsa-miR-4252 (MIRT680741)
- hsa-miR-2277-3p (MIRT680742)
- hsa-miR-4793-3p (MIRT680743)
- hsa-miR-766-3p (MIRT680744)
- hsa-miR-6849-3p (MIRT680745)
- hsa-miR-1273g-3p (MIRT680746)
- hsa-miR-3940-3p (MIRT680747)
- hsa-miR-508-5p (MIRT680748)
- hsa-miR-1292-3p (MIRT682764)
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for CA5B
- Browse OriGene Inhibitory RNA Products For CA5B
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for CA5B
Clone Products
- Applied Biological Materials (abm): Clones for CA5B - Select products 50% OFF >
- * CA5B as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for CA5B
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for CA5B
Cell Line Products
-
Horizon Cell Lines for CA5B
No data available for Phenotypes From GWAS Catalog , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for CA5B Gene
Localization for CA5B Gene
Subcellular locations from UniProtKB/Swiss-Prot for CA5B Gene
- Mitochondrion.
| Compartment | Confidence |
|---|---|
| mitochondrion | 5 |
| plasma membrane | 2 |
| extracellular | 2 |
| nucleus | 2 |
| cytosol | 2 |
| cytoskeleton | 1 |
| peroxisome | 1 |
| endoplasmic reticulum | 1 |
| endosome | 1 |
| lysosome | 1 |
| golgi apparatus | 1 |
- Mitochondria (3)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005737 | cytoplasm | IBA | 21873635 |
| GO:0005739 | mitochondrion | TAS,IDA | -- |
| GO:0005759 | mitochondrial matrix | TAS | -- |
Pathways & Interactions for CA5B Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Metabolism |
.40
|
|
| 2 | Nitrogen metabolism | ||
Pathways by source for CA5B Gene
2 Reactome pathways for CA5B Gene
2 KEGG pathways for CA5B Gene
Interacting Proteins for CA5B Gene
GPS-Prot Interaction Network for CA5B
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006730 | one-carbon metabolic process | IBA | 21873635 |
| GO:0009617 | response to bacterium | IEA | -- |
| GO:0015701 | bicarbonate transport | TAS | -- |
No data available for SIGNOR curated interactions for CA5B Gene
Drugs & Compounds for CA5B Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| Zonisamide | Approved, Investigational | Pharma | Target, inhibitor | Antiepileptic with anticonvulsant and mechanistic effect | 74 | |
| Benzthiazide | Approved | Pharma | Target, inhibitor | 0 | ||
| Cyclothiazide | Approved | Pharma | Allosteric regulator, Positive, Target, inhibitor | 0 | ||
| Carbon dioxide | Approved, Investigational, Vet_approved | Pharma | 0 | |||
| Water | Approved | Pharma | 0 |
| Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs | |
|---|---|---|---|---|---|---|
| Carbonic acid |
|
71-52-3, 463-79-6 |
|
Drug Products
- G Biosciences Human Carbonic Anhydrase VB/CA5B, Liquid
Transcripts for CA5B Gene
mRNA/cDNA for CA5B Gene
- 1 REFSEQ mRNAs :
- 6 NCBI additional mRNA sequence :
- 10 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000498004 488 nts (view in UCSC)
- ENST00000318636 6837 nts (view in UCSC)
- ENST00000478923 578 nts (view in UCSC)
- ENST00000474624 565 nts (view in UCSC)
- ENST00000380319 652 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for CA5B - Select products 50% OFF >
- * CA5B CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for CA5B
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for CA5B
-
Santa Cruz Biotechnology (SCBT) CRISPR for CA5B
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for CA5B
- Browse OriGene Inhibitory RNA Products For CA5B
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for CA5B
Clone Products
- Applied Biological Materials (abm): Clones for CA5B - Select products 50% OFF >
- * CA5B as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for CA5B
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for CA5B
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3a | · | 3b | · | 3c | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | ^ | 7 | ^ | 8a | · | 8b | ^ | 9 | ^ | 10 | ^ | 11 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | |||||||||||||||||||||||||||||
| SP2: | - | - | - | - | - | - | |||||||||||||||||||||||||||
| SP3: | - | - | |||||||||||||||||||||||||||||||
| SP4: | - | - | - | - | |||||||||||||||||||||||||||||
| SP5: | - | ||||||||||||||||||||||||||||||||
| SP6: | - | - | |||||||||||||||||||||||||||||||
| SP7: | - | - | |||||||||||||||||||||||||||||||
| SP8: | - | - |
Relevant External Links for CA5B Gene
- GeneLoc Exon Structure for
- CA5B
Expression for CA5B Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Inner Cell Mass (Early Embryonic Tissues)
-
Kidney (Urinary System)
- Ureteric Bud Cells Ureteric Bud
-
Brain (Nervous System)
- Mature Choroid Plexus Cells Choroid Plexus
-
Epithelial Cells
- Mature Choroid Plexus Cells Choroid Plexus
- Adipose (Muscoskeletal System)
This gene is overexpressed in Lymph node (10.4), Testis (7.9), Thyroid (7.2), and CD8 Tcells (6.6).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for CA5B Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for CA5B
SOURCE GeneReport for Unigene cluster for CA5B Gene:
Hs.653287mRNA Expression by UniProt/SwissProt for CA5B Gene:
Q9Y2D0-CAH5B_HUMAN
Tissue specificity:
Strongest expression in heart, pancreas, kidney, placenta, lung, and skeletal muscle. Not expressed in liver.
Evidence on tissue expression from TISSUES for CA5B Gene
- Blood(4.5)
- Pancreas(4.3)
- Nervous system(3.5)
- Heart(2.6)
- Liver(2.3)
- Muscle(2.2)
- Intestine(2.2)
- Kidney(2.2)
Primer Products
-
OriGene qPCR primer pairs for CA5B
Gene Expression Assay Products
No data available for mRNA differential expression in normal tissues , Protein tissue co-expression partners and Phenotype-based relationships between genes and organs from Gene ORGANizer for CA5B Gene
Orthologs for CA5B Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | CA5B 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | CA5B 30 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | CA5B 30 31 |
|
OneToOne | |
| Mouse (Mus musculus) |
Mammalia | Car5b 30 17 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Car5b 30 |
|
||
| Oppossum (Monodelphis domestica) |
Mammalia | CA5B 31 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | CA5B 31 |
|
OneToOne | |
| Chicken (Gallus gallus) |
Aves | CA5B 30 |
|
||
| -- 31 |
|
OneToMany | |||
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | ca5b 30 |
|
||
| Str.16738 30 |
|
||||
| African clawed frog (Xenopus laevis) |
Amphibia | Xl.25642 30 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | ca5 30 31 |
|
OneToMany | |
| Fruit Fly (Drosophila melanogaster) |
Insecta | CAH1 31 |
|
OneToMany | |
| Worm (Caenorhabditis elegans) |
Secernentea | cah-3 32 |
|
|
- Species where no ortholog for CA5B was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Lizard (Anolis carolinensis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
Evolution for CA5B Gene
- ENSEMBL:
- Gene Tree for CA5B (if available)
- TreeFam:
- Gene Tree for CA5B (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for CA5B: view image
Paralogs for CA5B Gene
Paralogs for CA5B Gene
(10) SIMAP similar genes for CA5B Gene using alignment to 4 proteins:
- CAH5B_HUMAN
- C9IZP3_HUMAN
- C9JA11_HUMAN
- H7C4G3_HUMAN
Pseudogenes.org Pseudogenes for CA5B Gene
Variants for CA5B Gene
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv2739978 | CNV | deletion | 23290073 |
Residual Variation Intolerance Score:
27.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
1.04;
21.30% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for CA5B Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- CA5B
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for CA5B Gene
Disorders for CA5B Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| second-degree atrioventricular block |
|
|
| mobitz type ii atrioventricular block |
|
|
| aortic valve prolapse |
|
|
| carbonic anhydrase va deficiency |
|
|
| third-degree atrioventricular block |
|
|
Search CA5B in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for CA5B
No data available for UniProtKB/Swiss-Prot and Genatlas for CA5B Gene
Publications for CA5B Gene
- Human mitochondrial carbonic anhydrase VB. cDNA cloning, mRNA expression, subcellular localization, and mapping to chromosome x. (PMID: 10409679) Fujikawa-Adachi K … Onishi S (The Journal of biological chemistry 1999) 2 3 4 23
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4
- Carbonic anhydrase isozymes in the human pancreas. (PMID: 11303978) Nishimori I … Onishi S (Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2001) 3 23
- Mitochondrial carbonic anhydrase CA VB: differences in tissue distribution and pattern of evolution from those of CA VA suggest distinct physiological roles. (PMID: 10677517) Shah GN … Sly WS (Proceedings of the National Academy of Sciences of the United States of America 2000) 3 23
ExternalLinks
Products for CA5B Gene
- View all 4 R&D Systems CA5B (Carbonic Anhydrase VB/CA5B) Products
- View all R&D Systems CA5B (Carbonic Anhydrase VB/CA5B) Proteins and Enzymes
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- Learn more about R&D Systems custom CA5B antibody, protein, and immunoassay development services
- Custom Antibody ServicesOriGene Antibodies for CA5B
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- Custom Assay Services
- Search Origene for MassSpec and Protein Over-expression Lysates for CA5B
- Origene Custom Protein Services for CA5B
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- Browse OriGene Inhibitory RNA Products For CA5B
- OriGene qPCR primer pairs for CA5B
- OriGene CRISPR knockouts for CA5B
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- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
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- Novus Biologicals Antibodies for CA5B
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- Find your target
- Browse Primary Antibodies
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- Browse ELISA Kits
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- Invitrogen Antibodies for CA5B (AFLGC-CA5B)
- VectorBuilder Custom and pre-made DNA vectors for CA5B (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for CA5B (ie. lentivirus, AAV, adenovirus)
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- VectorBuilder Virus packaging for CA5B CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for CA5B
- antibodies-online: Show 21 available CA5B Antibodies ranked by validation data
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- antibodies-online: Show 22 available CA5B Elisa Kits ranked by validation data
- Compare Top CA5B Elisa Kits
- Quality Products:
- antibodies-online: Show 15 available CA5B Proteins ranked by validation data
- Compare Top CA5B Proteins
- Santa Cruz Biotechnology (SCBT) Antibodies for CA5B
- Search Santa Cruz Biotechnology (SCBT) for CA5B siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for CA5B
- Search for CA5B Antibodies at ProSci
- Custom Antibody Services
- ProSci Proteins for CA5B
- Horizon Cell Lines for CA5B
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for CA5B
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for CA5B
- Search GeneCopoeia for miRNA 3'UTR Target clone products for CA5B
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for CA5B
Sources for CA5B Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB