Aliases for CA11 Gene
External Ids for CA11 Gene
Previous GeneCards Identifiers for CA11 Gene
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA XI is likely a secreted protein, however, radical changes at active site residues completely conserved in CA isozymes with catalytic activity, make it unlikely that it has carbonic anhydrase activity. It shares properties in common with two other acatalytic CA isoforms, CA VIII and CA X. CA XI is most abundantly expressed in brain, and may play a general role in the central nervous system. [provided by RefSeq, Jul 2008]
GeneCards Summary for CA11 Gene
CA11 (Carbonic Anhydrase 11) is a Protein Coding gene. Diseases associated with CA11 include Sialolithiasis. Gene Ontology (GO) annotations related to this gene include carbonate dehydratase activity. An important paralog of this gene is CA10.
UniProtKB/Swiss-Prot Summary for CA11 Gene
Does not have a catalytic activity.