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Aliases for C9orf170 Gene

Aliases for C9orf170 Gene

  • Chromosome 9 Open Reading Frame 170 2 3 5

External Ids for C9orf170 Gene

Previous GeneCards Identifiers for C9orf170 Gene

  • GC09P088954
  • GC09P089763
  • GC09P059590

Summaries for C9orf170 Gene

GeneCards Summary for C9orf170 Gene

C9orf170 (Chromosome 9 Open Reading Frame 170) is a Protein Coding gene.

Additional gene information for C9orf170 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C9orf170 Gene

Genomics for C9orf170 Gene

GeneHancer (GH) Regulatory Elements for C9orf170 Gene

Promoters and enhancers for C9orf170 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH09I087146 Promoter/Enhancer 1.4 Ensembl ENCODE dbSUPER 559 +0.0 46 3.4 ATF1 ZBTB40 RAD21 YY1 POLR2A PHF20 SCRT2 NFE2 ATF7 CREM C9orf170 GAS1RR GC09P087261
GH09I087266 Enhancer 1.4 FANTOM5 Ensembl ENCODE dbSUPER 14.2 +120.6 120609 5.6 ZSCAN4 MZF1 FEZF1 ZNF2 ZNF335 ZNF302 FOS EGR2 RXRA OVOL3 C9orf170 GAS1RR GAS1 ENSG00000212421 LOC105376126
GH09I087370 Enhancer 1.3 Ensembl ENCODE dbSUPER 10 +225.0 224964 6.9 FOXA2 SIN3A FEZF1 BATF RAD21 RARA YY1 GTF3C2 ZNF335 ZNF302 DAPK1 C9orf170 GC09P087365 GC09P087366 GC09P087367 GC09P087368 GC09P087380
GH09I087122 Enhancer 0.6 Ensembl ENCODE 12.1 -25.2 -25228 1.7 JUND POLR2A ZNF529 C9orf170 ENSG00000212421 GAS1RR GC09P087131 LOC494127
GH09I087274 Enhancer 1 Ensembl ENCODE dbSUPER 6.1 +127.9 127906 3.7 YY2 ZBTB11 ZIC2 JUND ZSCAN16 POLR2A BCL11A GLIS1 IKZF1 PRDM4 C9orf170 LOC105376126 ENSG00000212421
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around C9orf170 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the C9orf170 gene promoter:

Genomic Locations for C9orf170 Gene

Genomic Locations for C9orf170 Gene
11,083 bases
Plus strand

Genomic View for C9orf170 Gene

Genes around C9orf170 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C9orf170 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C9orf170 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C9orf170 Gene

Proteins for C9orf170 Gene

  • Protein details for C9orf170 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Uncharacterized protein C9orf170
    Protein Accession:

    Protein attributes for C9orf170 Gene

    121 amino acids
    Molecular mass:
    13369 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C9orf170 Gene

Post-translational modifications for C9orf170 Gene

No Post-translational modifications

Other Protein References for C9orf170 Gene

REFSEQ proteins:

No data available for DME Specific Peptides for C9orf170 Gene

Domains & Families for C9orf170 Gene

Protein Domains for C9orf170 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C9orf170: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C9orf170 Gene

Function for C9orf170 Gene

Phenotypes for C9orf170 Gene

GenomeRNAi human phenotypes for C9orf170:
genes like me logo Genes that share phenotypes with C9orf170: view

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C9orf170 Gene

Localization for C9orf170 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for C9orf170 gene
Compartment Confidence
mitochondrion 3
extracellular 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for C9orf170 Gene

Pathways & Interactions for C9orf170 Gene

SuperPathways for C9orf170 Gene

No Data Available

Interacting Proteins for C9orf170 Gene

Gene Ontology (GO) - Biological Process for C9orf170 Gene


No data available for Pathways by source and SIGNOR curated interactions for C9orf170 Gene

Drugs & Compounds for C9orf170 Gene

No Compound Related Data Available

Transcripts for C9orf170 Gene

mRNA/cDNA for C9orf170 Gene

(1) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(5) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for C9orf170 Gene

Chromosome 9 open reading frame 170:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for C9orf170 Gene

No ASD Table

Relevant External Links for C9orf170 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C9orf170 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for C9orf170 Gene

NURSA nuclear receptor signaling pathways regulating expression of C9orf170 Gene:


SOURCE GeneReport for Unigene cluster for C9orf170 Gene:

genes like me logo Genes that share expression patterns with C9orf170: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for C9orf170 Gene

Orthologs for C9orf170 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for C9orf170 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia C9H9orf170 33
  • 97.8 (n)
C9orf170 34
  • 93 (a)
Species where no ortholog for C9orf170 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C9orf170 Gene

Gene Tree for C9orf170 (if available)
Gene Tree for C9orf170 (if available)

Paralogs for C9orf170 Gene

No data available for Paralogs for C9orf170 Gene

Variants for C9orf170 Gene

Sequence variations from dbSNP and Humsavar for C9orf170 Gene

SNP ID Clin Chr 09 pos Variation AA Info Type
rs1000969197 -- 87,157,956(+) C/A 3_prime_UTR_variant
rs1001281339 -- 87,155,275(+) T/G intron_variant
rs1001486842 -- 87,148,655(+) C/A 5_prime_UTR_variant
rs1001492486 -- 87,157,248(+) A/T 3_prime_UTR_variant
rs1002228033 -- 87,149,600(+) G/A intron_variant

Structural Variations from Database of Genomic Variants (DGV) for C9orf170 Gene

Variant ID Type Subtype PubMed ID
nsv466430 CNV loss 19166990
nsv614785 CNV loss 21841781

Variation tolerance for C9orf170 Gene

Residual Variation Intolerance Score: 71.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.39; 8.67% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for C9orf170 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C9orf170 Gene

Disorders for C9orf170 Gene

Additional Disease Information for C9orf170

No disorders were found for C9orf170 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C9orf170 Gene

Publications for C9orf170 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
  3. A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder. (PMID: 20889312) Wang KS … Aragam N (Schizophrenia research 2010) 44 58
  4. Genome-wide association with bone mass and geometry in the Framingham Heart Study. (PMID: 17903296) Kiel DP … Karasik D (BMC medical genetics 2007) 44 58
  5. A genome-wide association study identifies IL23R as an inflammatory bowel disease gene. (PMID: 17068223) Duerr RH … Cho JH (Science (New York, N.Y.) 2006) 44 58

Products for C9orf170 Gene

Sources for C9orf170 Gene

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