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Aliases for C8orf87 Gene

Aliases for C8orf87 Gene

  • Chromosome 8 Open Reading Frame 87 2 3 5
  • Uncharacterized Protein C8orf87 3

External Ids for C8orf87 Gene

Previous GeneCards Identifiers for C8orf87 Gene

  • GC08M094146

Summaries for C8orf87 Gene

GeneCards Summary for C8orf87 Gene

C8orf87 (Chromosome 8 Open Reading Frame 87) is a Protein Coding gene.

Additional gene information for C8orf87 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C8orf87 Gene

Genomics for C8orf87 Gene

GeneHancer (GH) Regulatory Elements for C8orf87 Gene

Promoters and enhancers for C8orf87 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH08J093218 Enhancer 0.7 ENCODE dbSUPER 0.2 -52.0 -51957 0.2 NCOA3 PKNOX1 GATA3 CREB1 DPF2 FOS LOC105375643 ENSG00000253960 C8orf87 LINC00535
GH08J093215 Enhancer 0.7 ENCODE dbSUPER 0.2 -50.2 -50152 2.6 SP1 NANOG POU5F1 CREB1 SIN3A FOS FOXA1 LOC105375643 ENSG00000253960 C8orf87 LINC00535
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around C8orf87 on UCSC Golden Path with GeneCards custom track

Genomic Locations for C8orf87 Gene

Genomic Locations for C8orf87 Gene
chr8:93,134,095-93,166,850
(GRCh38/hg38)
Size:
32,756 bases
Orientation:
Minus strand
chr8:94,146,324-94,179,079
(GRCh37/hg19)
Size:
32,756 bases
Orientation:
Minus strand

Genomic View for C8orf87 Gene

Genes around C8orf87 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C8orf87 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C8orf87 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C8orf87 Gene

Proteins for C8orf87 Gene

  • Protein details for C8orf87 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    E5RJ46-CH087_HUMAN
    Recommended name:
    Uncharacterized protein C8orf87
    Protein Accession:
    E5RJ46

    Protein attributes for C8orf87 Gene

    Size:
    101 amino acids
    Molecular mass:
    11413 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C8orf87 Gene

Post-translational modifications for C8orf87 Gene

No Post-translational modifications

Other Protein References for C8orf87 Gene

REFSEQ proteins:

No data available for DME Specific Peptides for C8orf87 Gene

Domains & Families for C8orf87 Gene

Protein Domains for C8orf87 Gene

ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C8orf87: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C8orf87 Gene

Function for C8orf87 Gene

Phenotypes From GWAS Catalog for C8orf87 Gene

Phenotypes for C8orf87 Gene

genes like me logo Genes that share phenotypes with C8orf87: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for C8orf87

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for C8orf87 Gene

Localization for C8orf87 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for C8orf87 Gene

Pathways & Interactions for C8orf87 Gene

SuperPathways for C8orf87 Gene

No Data Available

Interacting Proteins for C8orf87 Gene

Gene Ontology (GO) - Biological Process for C8orf87 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C8orf87 Gene

Drugs & Compounds for C8orf87 Gene

No Compound Related Data Available

Transcripts for C8orf87 Gene

mRNA/cDNA for C8orf87 Gene

(1) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(2) Selected AceView cDNA sequences:
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :
(3) RNA Central transcripts :

Unigene Clusters for C8orf87 Gene

Chromosome 8 open reading frame 87:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for C8orf87

Alternative Splicing Database (ASD) splice patterns (SP) for C8orf87 Gene

No ASD Table

Relevant External Links for C8orf87 Gene

GeneLoc Exon Structure for
C8orf87
ECgene alternative splicing isoforms for
C8orf87

Expression for C8orf87 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for C8orf87 Gene

mRNA differential expression in normal tissues according to GTEx for C8orf87 Gene

This gene is overexpressed in Testis (x12.0), Kidney - Cortex (x6.8), and Brain - Putamen (basal ganglia) (x4.1).

NURSA nuclear receptor signaling pathways regulating expression of C8orf87 Gene:

C8orf87

SOURCE GeneReport for Unigene cluster for C8orf87 Gene:

Hs.386711
genes like me logo Genes that share expression patterns with C8orf87: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for C8orf87 Gene

Orthologs for C8orf87 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for C8orf87 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C8H8orf87 33
  • 98.35 (n)
Species where no ortholog for C8orf87 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C8orf87 Gene

ENSEMBL:
Gene Tree for C8orf87 (if available)
TreeFam:
Gene Tree for C8orf87 (if available)

Paralogs for C8orf87 Gene

No data available for Paralogs for C8orf87 Gene

Variants for C8orf87 Gene

Sequence variations from dbSNP and Humsavar for C8orf87 Gene

SNP ID Clin Chr 08 pos Variation AA Info Type
rs1000296236 -- 93,140,927(-) T/C intron_variant
rs1000506265 -- 93,163,648(-) T/C intron_variant
rs1000556390 -- 93,162,273(-) A/C intron_variant
rs1000783739 -- 93,168,718(-) G/A upstream_transcript_variant
rs1000805444 -- 93,147,157(-) A/G intron_variant

Structural Variations from Database of Genomic Variants (DGV) for C8orf87 Gene

Variant ID Type Subtype PubMed ID
esv3339915 CNV insertion 20981092
esv3420159 CNV insertion 20981092
nsv1022473 CNV loss 25217958
nsv465738 CNV loss 19166990
nsv472957 CNV novel sequence insertion 20440878
nsv611747 CNV loss 21841781
nsv824689 CNV gain 20364138
nsv831396 CNV gain 17160897

Variation tolerance for C8orf87 Gene

Gene Damage Index Score: 6.95; 79.80% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for C8orf87 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
C8orf87

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C8orf87 Gene

Disorders for C8orf87 Gene

Additional Disease Information for C8orf87

No disorders were found for C8orf87 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C8orf87 Gene

Publications for C8orf87 Gene

  1. A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder. (PMID: 20889312) Wang KS … Aragam N (Schizophrenia research 2010) 3 58
  2. DNA sequence and analysis of human chromosome 8. (PMID: 16421571) Nusbaum C … Lander ES (Nature 2006) 4 58
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 4 58
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 58

Products for C8orf87 Gene

Sources for C8orf87 Gene

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