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Aliases for C8orf82 Gene

Aliases for C8orf82 Gene

  • Chromosome 8 Open Reading Frame 82 2 3 5

External Ids for C8orf82 Gene

Previous GeneCards Identifiers for C8orf82 Gene

  • GC08M145723
  • GC08M145751
  • GC08M140865

Summaries for C8orf82 Gene

GeneCards Summary for C8orf82 Gene

C8orf82 (Chromosome 8 Open Reading Frame 82) is a Protein Coding gene.

Additional gene information for C8orf82 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C8orf82 Gene

Genomics for C8orf82 Gene

GeneHancer (GH) Regulatory Elements for C8orf82 Gene

Promoters and enhancers for C8orf82 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH08I144528 Promoter/Enhancer 2.2 EPDnew Ensembl ENCODE dbSUPER 561.5 +0.1 143 1.6 HDGF ARID4B SIN3A FEZF1 DMAP1 SLC30A9 ZNF213 ZNF207 ZNF143 SP3 C8orf82 LRRC24 ARHGAP39
GH08I144529 Enhancer 0.7 ENCODE dbSUPER 550.8 -0.9 -853 0.3 ZNF148 CTCF AFF1 ZBTB6 SIN3A ZBTB33 C8orf82 ENSG00000255456 ARHGAP39
GH08I144527 Enhancer 0.6 ENCODE dbSUPER 550.8 +1.3 1310 0 POLR2A ZBTB33 LRRC24 C8orf82
GH08I144059 Promoter/Enhancer 2.2 EPDnew Ensembl ENCODE dbSUPER 10 +468.8 468780 2.3 SMAD1 ARID4B SIN3A DMAP1 YY1 ZNF766 SP5 MXD4 REST ZNF592 OPLAH WDR97 ENSG00000255224 ZNF7 ZNF251 ZNF623 ZNF16 GPAA1 ZNF250 LRRC14
GH08I144455 Enhancer 1.3 Ensembl ENCODE 15.8 +72.7 72686 1.6 HDGF HNRNPUL1 PKNOX1 FOXA2 ARNT ZFP64 SIN3A ZNF2 POLR2B ZNF766 ZNF251 ZNF623 ZNF7 LRRC14 ZNF250 ZNF16 CPSF1 VPS28 ZNF517 ZNF34
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around C8orf82 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the C8orf82 gene promoter:

Genomic Locations for C8orf82 Gene

Genomic Locations for C8orf82 Gene
chr8:144,525,733-144,529,132
(GRCh38/hg38)
Size:
3,400 bases
Orientation:
Minus strand
chr8:145,751,117-145,754,516
(GRCh37/hg19)

Genomic View for C8orf82 Gene

Genes around C8orf82 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C8orf82 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C8orf82 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C8orf82 Gene

Proteins for C8orf82 Gene

  • Protein details for C8orf82 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6P1X6-CH082_HUMAN
    Recommended name:
    UPF0598 protein C8orf82
    Protein Accession:
    Q6P1X6
    Secondary Accessions:
    • Q6GMR2
    • Q6P2Q7

    Protein attributes for C8orf82 Gene

    Size:
    216 amino acids
    Molecular mass:
    23889 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for C8orf82 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for C8orf82 Gene

Post-translational modifications for C8orf82 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C8orf82 Gene

No data available for DME Specific Peptides for C8orf82 Gene

Domains & Families for C8orf82 Gene

Gene Families for C8orf82 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for C8orf82 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for C8orf82 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q6P1X6

UniProtKB/Swiss-Prot:

CH082_HUMAN :
  • Belongs to the UPF0598 family.
Family:
  • Belongs to the UPF0598 family.
genes like me logo Genes that share domains with C8orf82: view

Function for C8orf82 Gene

Phenotypes From GWAS Catalog for C8orf82 Gene

Phenotypes for C8orf82 Gene

genes like me logo Genes that share phenotypes with C8orf82: view

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C8orf82 Gene

Localization for C8orf82 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for C8orf82 gene
Compartment Confidence
mitochondrion 3
nucleus 2
peroxisome 1
cytosol 1

Subcellular locations from the

Human Protein Atlas (HPA)

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C8orf82 Gene

Pathways & Interactions for C8orf82 Gene

SuperPathways for C8orf82 Gene

No Data Available

Interacting Proteins for C8orf82 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
http://version10.5.string-db.org/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000434593%0d%0a9606.ENSP00000452762%0d%0a
Selected Interacting proteins: ENSP00000434593 Q6P1X6-CH082_HUMAN for C8orf82 Gene via STRING IID

Gene Ontology (GO) - Biological Process for C8orf82 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C8orf82 Gene

Drugs & Compounds for C8orf82 Gene

No Compound Related Data Available

Transcripts for C8orf82 Gene

Unigene Clusters for C8orf82 Gene

Chromosome 8 open reading frame 82:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for C8orf82 Gene

No ASD Table

Relevant External Links for C8orf82 Gene

GeneLoc Exon Structure for
C8orf82
ECgene alternative splicing isoforms for
C8orf82

Expression for C8orf82 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for C8orf82 Gene

Protein differential expression in normal tissues from HIPED for C8orf82 Gene

This gene is overexpressed in Liver (6.4).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for C8orf82 Gene



Protein tissue co-expression partners for C8orf82 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of C8orf82 Gene:

C8orf82

SOURCE GeneReport for Unigene cluster for C8orf82 Gene:

Hs.105685
genes like me logo Genes that share expression patterns with C8orf82: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for C8orf82 Gene

Orthologs for C8orf82 Gene

This gene was present in the common ancestor of animals.

Orthologs for C8orf82 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C8H8orf82 33
  • 98.92 (n)
C8ORF82 34
  • 98 (a)
OneToOne
cow
(Bos Taurus)
Mammalia C14H8orf82 33 34
  • 87.8 (n)
mouse
(Mus musculus)
Mammalia C030006K11Rik 33 16 34
  • 84.1 (n)
rat
(Rattus norvegicus)
Mammalia MGC94207 33
  • 83.33 (n)
oppossum
(Monodelphis domestica)
Mammalia C8orf82 34
  • 64 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C8orf82 34
  • 27 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii C20H8orf82 34
  • 55 (a)
OneToOne
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP011455 33
  • 56.87 (n)
fruit fly
(Drosophila melanogaster)
Insecta CG30010 33 34
  • 56.76 (n)
worm
(Caenorhabditis elegans)
Secernentea CELE_F59C6.12 33
  • 50 (n)
F59C6.12 34
  • 43 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea -- 34
  • 42 (a)
OneToOne
Species where no ortholog for C8orf82 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for C8orf82 Gene

ENSEMBL:
Gene Tree for C8orf82 (if available)
TreeFam:
Gene Tree for C8orf82 (if available)

Paralogs for C8orf82 Gene

No data available for Paralogs for C8orf82 Gene

Variants for C8orf82 Gene

Sequence variations from dbSNP and Humsavar for C8orf82 Gene

SNP ID Clin Chr 08 pos Variation AA Info Type
rs1000833019 -- 144,528,213(-) G/A intron_variant
rs1000962468 -- 144,530,022(-) A/G upstream_transcript_variant
rs1001058798 -- 144,531,044(-) C/T upstream_transcript_variant
rs1001077080 -- 144,529,899(-) C/A upstream_transcript_variant
rs1002105448 -- 144,529,066(-) C/T 5_prime_UTR_variant

Structural Variations from Database of Genomic Variants (DGV) for C8orf82 Gene

Variant ID Type Subtype PubMed ID
dgv1207n67 CNV gain 20364138
dgv3935n106 CNV deletion 24896259
nsv428208 CNV gain 18775914
nsv522459 CNV loss 19592680
nsv612940 CNV loss 21841781
nsv612951 CNV loss 21841781
nsv831489 CNV loss 17160897

Additional Variant Information for C8orf82 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
C8orf82

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for C8orf82 Gene

Disorders for C8orf82 Gene

Additional Disease Information for C8orf82

No disorders were found for C8orf82 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C8orf82 Gene

Publications for C8orf82 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 2 3 58
  2. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 58
  3. Quantitative Proteomics Reveals Dynamic Interactions of the Minichromosome Maintenance Complex (MCM) in the Cellular Response to Etoposide Induced DNA Damage. (PMID: 25963833) Drissi R … Boisvert FM (Molecular & cellular proteomics : MCP 2015) 3 58
  4. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin EL … Gygi SP (Cell 2015) 3 58
  5. N-terminome analysis of the human mitochondrial proteome. (PMID: 25944712) Vaca Jacome AS … Carapito C (Proteomics 2015) 4 58

Products for C8orf82 Gene

Sources for C8orf82 Gene

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