Aliases for C8orf44 Gene

Subcategory (RNA class) for C8orf44 Gene

lncRNA

Number of RNA Genes sources:

2 / 17

Aliases for C8orf44 Gene

  • Chromosome 8 Open Reading Frame 44 2 3 5
  • Putative Uncharacterized Protein C8orf44 4
  • NONHSAG050420.2 91
  • HSALNG0065906 164
  • FLJ11267 2
  • C8orf44 5

External Ids for C8orf44 Gene

Previous GeneCards Identifiers for C8orf44 Gene

  • GC08P067743
  • GC08P067588
  • GC08P063080

Summaries for C8orf44 Gene

GeneCards Summary for C8orf44 Gene

C8orf44 (Chromosome 8 Open Reading Frame 44) is an RNA Gene, and is affiliated with the lncRNA class.

Additional gene information for C8orf44 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for C8orf44 Gene

Genomics for C8orf44 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for C8orf44 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around C8orf44 on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for C8orf44

Top Transcription factor binding sites by QIAGEN in the C8orf44 gene promoter:
  • COUP
  • COUP-TF
  • COUP-TF1
  • CUTL1
  • FOXO1
  • FOXO1a
  • HNF-4alpha1
  • HNF-4alpha2
  • ITF-2
  • Tal-1beta

Genomic Locations for C8orf44 Gene

Genomic Locations for C8orf44 Gene
chr8:66,667,552-66,685,564
(GRCh38/hg38)
Size:
18,013 bases
Orientation:
Plus strand
chr8:67,579,787-67,597,799
(GRCh37/hg19)
Size:
18,013 bases
Orientation:
Plus strand

Genomic View for C8orf44 Gene

Genes around C8orf44 on UCSC Golden Path with GeneCards custom track
C8orf44 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
C8orf44 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C8orf44 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C8orf44 Gene

Proteins for C8orf44 Gene

  • Protein details for C8orf44 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96CB5-CH044_HUMAN
    Recommended name:
    Putative uncharacterized protein C8orf44
    Protein Accession:
    Q96CB5
    Secondary Accessions:
    • Q9NUM6

    Protein attributes for C8orf44 Gene

    Size:
    159 amino acids
    Molecular mass:
    18380 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C8orf44 Gene

Post-translational modifications for C8orf44 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C8orf44 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for C8orf44 Gene

Domains & Families for C8orf44 Gene

Gene Families for C8orf44 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for C8orf44 Gene

ProtoNet:
genes like me logo Genes that share domains with C8orf44: view

No data available for Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for C8orf44 Gene

Function for C8orf44 Gene

genes like me logo Genes that share phenotypes with C8orf44: view

Animal Model Products

CRISPR Products

miRNA for C8orf44 Gene

miRTarBase miRNAs that target C8orf44

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for C8orf44

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C8orf44 Gene

Localization for C8orf44 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for C8orf44 gene
Compartment Confidence
nucleus 4
extracellular 1
cytosol 1
plasma membrane 0

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for C8orf44 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005654 nucleoplasm IDA --
genes like me logo Genes that share ontologies with C8orf44: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for C8orf44 Gene

Pathways & Interactions for C8orf44 Gene

PathCards logo

SuperPathways for C8orf44 Gene

No Data Available

Gene Ontology (GO) - Biological Process for C8orf44 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for C8orf44 Gene

Drugs & Compounds for C8orf44 Gene

No Compound Related Data Available

Transcripts for C8orf44 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for C8orf44 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS0000E60A23_9606 lncRNA 2230 1

RefSeq: NR_161216,

URS0000E60A41_9606 lncRNA 1917 1

RefSeq: NR_161217,

URS0000EEEB82_9606 lncRNA 1835 1

Ensembl: ENST00000661636 (view in UCSC) ,

URS0000EF5DB4_9606 lncRNA 1817 1

Ensembl: ENST00000390159 (view in UCSC) ,

URS0000E60AC5_9606 lncRNA 654 1

RefSeq: NR_161218,

C8orf44 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Additional transcripts not in RNAcentral for C8orf44 Gene

1 REFSEQ mRNAs :
4 NCBI additional mRNA sequence :
3 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for C8orf44

Alternative Splicing Database (ASD) splice patterns (SP) for C8orf44 Gene

No ASD Table

Relevant External Links for C8orf44 Gene

GeneLoc Exon Structure for
C8orf44

Expression for C8orf44 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for C8orf44 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for C8orf44

SOURCE GeneReport for Unigene cluster for C8orf44 Gene:

Hs.661238

Evidence on tissue expression from TISSUES for C8orf44 Gene

  • Pancreas(4.2)
  • Nervous system(2.8)
genes like me logo Genes that share expression patterns with C8orf44: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for C8orf44 Gene

Orthologs for C8orf44 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for C8orf44 Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia C8H8orf44 30
  • 98.31 (n)
Species where no ortholog for C8orf44 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • Cow (Bos Taurus)
  • Dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Lizard (Anolis carolinensis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Mouse (Mus musculus)
  • Oppossum (Monodelphis domestica)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Platypus (Ornithorhynchus anatinus)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rat (Rattus norvegicus)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Tropical Clawed Frog (Silurana tropicalis)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)
  • Zebrafish (Danio rerio)

Evolution for C8orf44 Gene

ENSEMBL:
Gene Tree for C8orf44 (if available)
TreeFam:
Gene Tree for C8orf44 (if available)

Paralogs for C8orf44 Gene

(16) SIMAP similar genes for C8orf44 Gene using alignment to 2 proteins:

  • CH044_HUMAN
  • E5RJQ3_HUMAN
genes like me logo Genes that share paralogs with C8orf44: view

No data available for Paralogs for C8orf44 Gene

Variants for C8orf44 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for C8orf44 Gene

SNP ID Clinical significance and condition Chr 08 pos Variation AA Info Type
rs1057463 - p.Phe148Ser
rs1909534 - p.Gln131Arg

Additional dbSNP identifiers (rs#s) for C8orf44 Gene

Structural Variations from Database of Genomic Variants (DGV) for C8orf44 Gene

Variant ID Type Subtype PubMed ID
nsv831346 CNV loss 17160897

Variation tolerance for C8orf44 Gene

Residual Variation Intolerance Score: 78.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.50; 64.48% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for C8orf44 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
C8orf44

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C8orf44 Gene

Disorders for C8orf44 Gene

Additional Disease Information for C8orf44

No disorders were found for C8orf44 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C8orf44 Gene

Publications for C8orf44 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 2 3
  4. Dependence of Human Colorectal Cells Lacking the FBW7 Tumor Suppressor on the Spindle Assembly Checkpoint. (PMID: 26354767) Bailey ML … Hieter P (Genetics 2015) 3
  5. DNA sequence and analysis of human chromosome 8. (PMID: 16421571) Nusbaum C … Lander ES (Nature 2006) 4

Products for C8orf44 Gene

  • Signalway Proteins for C8orf44

Sources for C8orf44 Gene