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Aliases for C7orf71 Gene

Aliases for C7orf71 Gene

  • Chromosome 7 Open Reading Frame 71 2 3 5

External Ids for C7orf71 Gene

Previous GeneCards Identifiers for C7orf71 Gene

  • GC07P026645
  • GC07P026558

Summaries for C7orf71 Gene

GeneCards Summary for C7orf71 Gene

C7orf71 (Chromosome 7 Open Reading Frame 71) is a Protein Coding gene.

Additional gene information for C7orf71 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C7orf71 Gene

Genomics for C7orf71 Gene

GeneHancer (GH) Regulatory Elements for C7orf71 Gene

Promoters and enhancers for C7orf71 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH07I026372 Promoter/Enhancer 1.9 UCNEbase Ensembl ENCODE 9.3 -262.6 -262553 5.6 HDGF ARID4B SIN3A FEZF1 ZNF2 ZNF302 ZNF143 ZNF548 SP3 REST LOC105375304 HNRNPA2B1 HOXA10-AS HOXA9 CBX3 KIAA0087 C7orf71 SNX10 LOC441204 GC07P026242
GH07I025845 Enhancer 1.8 FANTOM5 Ensembl ENCODE dbSUPER 9.3 -785.0 -784960 14.1 HDGF PKNOX1 CLOCK FOXA2 ARNT SIN3A FEZF1 ZNF2 POLR2B ZNF766 HNRNPA2B1 C7orf31 LOC646588 TSEN15P3 ENSG00000202233 C7orf71 LOC100506236 GC07M025774
GH07I026397 Promoter/Enhancer 1.5 Ensembl ENCODE 10.8 -238.9 -238881 2.9 HDGF PKNOX1 ARNT ZNF2 GLIS2 KLF7 ATF7 RUNX3 SP3 JUNB LOC441204 LOC105375304 C7orf71 LOC105375202 GC07P026242
GH07I026485 Enhancer 1.5 VISTA UCNEbase ENCODE 10.7 -152.0 -151959 1 MXI1 PKNOX1 JUN FEZF1 CTBP1 ZNF350 SMARCC2 RCOR1 CHD2 SMARCC1 LOC105375304 C7orf71 LOC441204 ENSG00000280255 LOC105375202 GC07P026242
GH07I025860 Enhancer 1.4 Ensembl ENCODE dbSUPER 9.3 -775.9 -775942 3 HDGF PKNOX1 SIN3A FEZF1 POLR2B ZNF213 ZNF207 ZNF143 FOS SP3 LOC100506236 LOC646588 C7orf71 GC07M025774
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around C7orf71 on UCSC Golden Path with GeneCards custom track

Genomic Locations for C7orf71 Gene

Genomic Locations for C7orf71 Gene
chr7:26,637,488-26,651,531
(GRCh38/hg38)
Size:
14,044 bases
Orientation:
Plus strand
chr7:26,677,490-26,686,924
(GRCh37/hg19)

Genomic View for C7orf71 Gene

Genes around C7orf71 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C7orf71 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C7orf71 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C7orf71 Gene

Proteins for C7orf71 Gene

  • Protein details for C7orf71 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A4D174-CG071_HUMAN
    Recommended name:
    Putative uncharacterized protein C7orf71
    Protein Accession:
    A4D174

    Protein attributes for C7orf71 Gene

    Size:
    169 amino acids
    Molecular mass:
    19096 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C7orf71 Gene

Post-translational modifications for C7orf71 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C7orf71 Gene

No data available for DME Specific Peptides for C7orf71 Gene

Domains & Families for C7orf71 Gene

Protein Domains for C7orf71 Gene

ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C7orf71: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C7orf71 Gene

Function for C7orf71 Gene

Phenotypes From GWAS Catalog for C7orf71 Gene

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for C7orf71 Gene

Localization for C7orf71 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for C7orf71 gene
Compartment Confidence
nucleus 2
cytosol 2
mitochondrion 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for C7orf71 Gene

Pathways & Interactions for C7orf71 Gene

SuperPathways for C7orf71 Gene

No Data Available

Interacting Proteins for C7orf71 Gene

Gene Ontology (GO) - Biological Process for C7orf71 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C7orf71 Gene

Drugs & Compounds for C7orf71 Gene

No Compound Related Data Available

Transcripts for C7orf71 Gene

mRNA/cDNA for C7orf71 Gene

(7) REFSEQ mRNAs :
(4) Additional mRNA sequences :
(11) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for C7orf71 Gene

Chromosome 7 open reading frame 71:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for C7orf71 Gene

No ASD Table

Relevant External Links for C7orf71 Gene

GeneLoc Exon Structure for
C7orf71
ECgene alternative splicing isoforms for
C7orf71

Expression for C7orf71 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for C7orf71 Gene

mRNA differential expression in normal tissues according to GTEx for C7orf71 Gene

This gene is overexpressed in Testis (x37.9).

NURSA nuclear receptor signaling pathways regulating expression of C7orf71 Gene:

C7orf71

SOURCE GeneReport for Unigene cluster for C7orf71 Gene:

Hs.413394
genes like me logo Genes that share expression patterns with C7orf71: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for C7orf71 Gene

Orthologs for C7orf71 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for C7orf71 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C7H7orf71 33
  • 99.41 (n)
C7orf71 34
  • 99 (a)
OneToOne
Species where no ortholog for C7orf71 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C7orf71 Gene

ENSEMBL:
Gene Tree for C7orf71 (if available)
TreeFam:
Gene Tree for C7orf71 (if available)

Paralogs for C7orf71 Gene

No data available for Paralogs for C7orf71 Gene

Variants for C7orf71 Gene

Sequence variations from dbSNP and Humsavar for C7orf71 Gene

SNP ID Clin Chr 07 pos Variation AA Info Type
rs1000101135 -- 26,639,094(+) G/A 5_prime_UTR_variant, intron_variant
rs1000142347 -- 26,647,577(+) C/T downstream_transcript_variant
rs1000316133 -- 26,637,475(+) G/A 5_prime_UTR_variant, genic_upstream_transcript_variant, upstream_transcript_variant
rs1000592751 -- 26,636,222(+) C/A 5_prime_UTR_variant, genic_upstream_transcript_variant, upstream_transcript_variant
rs1000769459 -- 26,641,947(+) A/G intron_variant

Structural Variations from Database of Genomic Variants (DGV) for C7orf71 Gene

Variant ID Type Subtype PubMed ID
esv2734161 CNV deletion 23290073
esv3303956 CNV mobile element insertion 20981092
esv3310045 CNV mobile element insertion 20981092
esv3323424 CNV insertion 20981092
esv3397248 CNV insertion 20981092
nsv1020378 CNV gain 25217958
nsv1076611 CNV duplication 25765185
nsv1137204 CNV deletion 24896259
nsv1140755 CNV deletion 24896259
nsv7393 OTHER inversion 18451855
nsv830929 CNV gain 17160897

Variation tolerance for C7orf71 Gene

Gene Damage Index Score: 4.73; 66.36% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for C7orf71 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
C7orf71

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C7orf71 Gene

Disorders for C7orf71 Gene

Additional Disease Information for C7orf71

No disorders were found for C7orf71 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C7orf71 Gene

Publications for C7orf71 Gene

  1. Human chromosome 7: DNA sequence and biology. (PMID: 12690205) Scherer SW … Tsui LC (Science (New York, N.Y.) 2003) 3 4 58
  2. Heritability and genetic association analysis of cognition in the Diabetes Heart Study. (PMID: 24684796) Cox AJ … Bowden DW (Neurobiology of aging 2014) 3 58
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 58
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 4 58
  5. Expressed sequence tag analysis of human RPE/choroid for the NEIBank Project: over 6000 non-redundant transcripts, novel genes and splice variants. (PMID: 12107410) Wistow G … Peterson K (Molecular vision 2002) 3 58

Products for C7orf71 Gene

Sources for C7orf71 Gene

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