Aliases for C7orf26 Gene

Aliases for C7orf26 Gene

  • Chromosome 7 Open Reading Frame 26 2 3 5
  • Uncharacterized Protein C7orf26 3 4

External Ids for C7orf26 Gene

Previous GeneCards Identifiers for C7orf26 Gene

  • GC07P006339
  • GC07P006374
  • GC07P006403
  • GC07P006596
  • GC07P006630
  • GC07P006635
  • GC07P006640
  • GC07P006644
  • GC07P006658
  • GC07P006590
  • GC07P006591
  • GC07P006594

Summaries for C7orf26 Gene

GeneCards Summary for C7orf26 Gene

C7orf26 (Chromosome 7 Open Reading Frame 26) is a Protein Coding gene.

Additional gene information for C7orf26 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for C7orf26 Gene

Genomics for C7orf26 Gene

GeneHancer (GH) Regulatory Elements for C7orf26 Gene

Promoters and enhancers for C7orf26 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around C7orf26 on UCSC Golden Path with GeneCards custom track

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for C7orf26

Top Transcription factor binding sites by QIAGEN in the C7orf26 gene promoter:
  • AML1a
  • AP-4
  • AREB6
  • C/EBPbeta
  • E47
  • HFH-1
  • Lmo2
  • Olf-1
  • p300
  • Tal-1beta

Genomic Locations for C7orf26 Gene

Genomic Locations for C7orf26 Gene
19,359 bases
Plus strand
18,710 bases
Plus strand

Genomic View for C7orf26 Gene

Genes around C7orf26 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C7orf26 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C7orf26 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C7orf26 Gene

Proteins for C7orf26 Gene

  • Protein details for C7orf26 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Uncharacterized protein C7orf26
    Protein Accession:
    Secondary Accessions:
    • Q9BQ43

    Protein attributes for C7orf26 Gene

    449 amino acids
    Molecular mass:
    50047 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for C7orf26 Gene


neXtProt entry for C7orf26 Gene

Post-translational modifications for C7orf26 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for C7orf26 Gene

Domains & Families for C7orf26 Gene

Gene Families for C7orf26 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for C7orf26 Gene

genes like me logo Genes that share domains with C7orf26: view

No data available for Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for C7orf26 Gene

Function for C7orf26 Gene

Phenotypes From GWAS Catalog for C7orf26 Gene

genes like me logo Genes that share phenotypes with C7orf26: view

Animal Model Products

CRISPR Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C7orf26 Gene

Localization for C7orf26 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for C7orf26 gene
Compartment Confidence
cytosol 2
plasma membrane 1
nucleus 1
peroxisome 0

Subcellular locations from the

Human Protein Atlas (HPA)
  • Cytosol (2)
  • Intermediate filaments (2)
  • Nucleoli (2)
  • Nucleoplasm (2)
See all subcellular structures

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C7orf26 Gene

Pathways & Interactions for C7orf26 Gene

PathCards logo

SuperPathways for C7orf26 Gene

No Data Available

Gene Ontology (GO) - Biological Process for C7orf26 Gene


No data available for Pathways by source and SIGNOR curated interactions for C7orf26 Gene

Drugs & Compounds for C7orf26 Gene

No Compound Related Data Available

Transcripts for C7orf26 Gene

mRNA/cDNA for C7orf26 Gene

6 NCBI additional mRNA sequence :
6 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for C7orf26 Gene

ExUns: 1a · 1b · 1c ^ 2a · 2b · 2c ^ 3a · 3b · 3c ^ 4 ^ 5a · 5b · 5c · 5d · 5e ^ 6 ^ 7a · 7b ^ 8 ^ 9a · 9b ^ 10a · 10b · 10c
SP1: - - - - - - - - - -
SP2: - - - - - -
SP3: - - -
SP4: - - - -
SP5: - - -
SP6: - - -
SP8: -
SP10: - - -

Relevant External Links for C7orf26 Gene

GeneLoc Exon Structure for

Expression for C7orf26 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for C7orf26 Gene

Protein differential expression in normal tissues from HIPED for C7orf26 Gene

This gene is overexpressed in Platelet (49.2) and CD4 Tcells (7.4).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for C7orf26 Gene

Protein tissue co-expression partners for C7orf26 Gene

- Elite partner

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for C7orf26

SOURCE GeneReport for Unigene cluster for C7orf26 Gene:


Evidence on tissue expression from TISSUES for C7orf26 Gene

  • Intestine(3)
  • Pancreas(3)
genes like me logo Genes that share expression patterns with C7orf26: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for C7orf26 Gene

Orthologs for C7orf26 Gene

This gene was present in the common ancestor of animals.

Orthologs for C7orf26 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia C7orf26 31
  • 100 (a)
C7H7orf26 30
  • 99.63 (n)
(Canis familiaris)
Mammalia C7orf26 31
  • 96 (a)
C6H7orf26 30
  • 91.22 (n)
(Bos Taurus)
Mammalia C25H7ORF26 31
  • 93 (a)
C25H7orf26 30
  • 88.52 (n)
(Rattus norvegicus)
Mammalia LOC683674 30
  • 88.47 (n)
(Mus musculus)
Mammalia E130309D02Rik 17 31 30
  • 88.1 (n)
(Monodelphis domestica)
Mammalia C7orf26 31
  • 84 (a)
(Ornithorhynchus anatinus)
Mammalia C7orf26 31
  • 77 (a)
(Gallus gallus)
Aves C7orf26 31
  • 84 (a)
C7ORF26 30
  • 79.36 (n)
(Anolis carolinensis)
Reptilia C7orf26 31
  • 70 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia c7orf26 30
  • 70.11 (n)
Str.18839 30
African clawed frog
(Xenopus laevis)
Amphibia MGC69165 30
(Danio rerio)
Actinopterygii zgc:56409 30
  • 63.78 (n)
C1H7orf26 31
  • 58 (a)
zgc56409 30
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP001655 30
  • 47.51 (n)
fruit fly
(Drosophila melanogaster)
Insecta CG5274 31 30
  • 46.33 (n)
Species where no ortholog for C7orf26 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for C7orf26 Gene

Gene Tree for C7orf26 (if available)
Gene Tree for C7orf26 (if available)

Paralogs for C7orf26 Gene

No data available for Paralogs for C7orf26 Gene

Variants for C7orf26 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for C7orf26 Gene

SNP ID Clinical significance and condition Chr 07 pos Variation AA Info Type
rs35534502 - p.Arg245Cys

Additional dbSNP identifiers (rs#s) for C7orf26 Gene

Structural Variations from Database of Genomic Variants (DGV) for C7orf26 Gene

Variant ID Type Subtype PubMed ID
dgv1090n67 CNV gain 20364138
dgv11172n54 CNV loss 21841781
dgv11173n54 CNV loss 21841781
esv1914954 OTHER inversion 16254605
esv2733932 CNV deletion 23290073
esv2733933 CNV deletion 23290073
nsv1020236 CNV gain 25217958
nsv436904 CNV insertion 17901297
nsv508444 CNV deletion 20534489
nsv515978 CNV loss 19592680
nsv606003 CNV loss 21841781
nsv7392 OTHER inversion 18451855
nsv830895 CNV loss 17160897
nsv950804 CNV deletion 24416366

Variation tolerance for C7orf26 Gene

Residual Variation Intolerance Score: 18.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.89; 48.57% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for C7orf26 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C7orf26 Gene

Disorders for C7orf26 Gene

Additional Disease Information for C7orf26

No disorders were found for C7orf26 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C7orf26 Gene

Publications for C7orf26 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 54
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 54
  3. Quantitative mapping of RNA-mediated nuclear estrogen receptor β interactome in human breast cancer cells. (PMID: 29509190) Giurato G … Tarallo R (Scientific data 2018) 3 54
  4. Panorama of ancient metazoan macromolecular complexes. (PMID: 26344197) Wan C … Emili A (Nature 2015) 3 54
  5. Interactome study suggests multiple cellular functions of hepatoma-derived growth factor (HDGF). (PMID: 21907836) Zhao J … Yang P (Journal of proteomics 2011) 3 54

Products for C7orf26 Gene

Sources for C7orf26 Gene