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Aliases for C7orf26 Gene

Aliases for C7orf26 Gene

  • Chromosome 7 Open Reading Frame 26 2 3 5

External Ids for C7orf26 Gene

Previous GeneCards Identifiers for C7orf26 Gene

  • GC07P006339
  • GC07P006374
  • GC07P006403
  • GC07P006596
  • GC07P006630
  • GC07P006635
  • GC07P006640
  • GC07P006644
  • GC07P006658

Summaries for C7orf26 Gene

GeneCards Summary for C7orf26 Gene

C7orf26 (Chromosome 7 Open Reading Frame 26) is a Protein Coding gene.

Additional gene information for C7orf26 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C7orf26 Gene

Genomics for C7orf26 Gene

GeneHancer (GH) Regulatory Elements for C7orf26 Gene

Promoters and enhancers for C7orf26 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH07I006589 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 550.8 +0.9 907 2 PKNOX1 ATF1 ARNT ARID4B SIN3A DMAP1 ZNF2 ZNF48 ZNF121 ELK1 C7orf26 GC07M006595 GC07M006596 GC07M006597 PIR47452 PIR57330 PIR59362 PIR36976 PIR45743 PIR61044
GH07I005591 Promoter/Enhancer 2.6 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 43.8 -993.9 -993915 8.6 HDGF PKNOX1 SMAD1 ARNT ARID4B SIN3A DMAP1 ZNF2 IRF4 YY1 FSCN1 C7orf26 AP5Z1 USP42 TNRC18 ANKRD61 CCZ1 RNF216P1 RBAK RNF216
GH07I006446 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 36.2 -140.6 -140584 4.4 CLOCK MLX ZFP64 FEZF1 YY1 SLC30A9 ZNF213 E2F8 ZNF143 ZC3H11A DAGLB ZNF316 C7orf26 ZNF12 USP42 ANKRD61 ENSG00000198580 ENSG00000228010 KDELR2 PMS2
GH07I005780 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 41.2 -808.0 -808038 1.9 HDGF PKNOX1 ARNT ARID4B SIN3A DMAP1 ZNF2 ZBTB7B POLR2B ZNF213 RNF216 C7orf26 ZNF316 TNRC18 ZNF12 USP42 RNF216P1 ANKRD61 KDELR2 PIR40049
GH07I007562 Promoter/Enhancer 2.8 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 24.8 +977.5 977527 8.2 HDGF PKNOX1 FOXA2 SMAD1 NEUROD1 SIN3A FEZF1 YBX1 ZNF2 IRF4 ENSG00000272894 MIOS LOC101927391 ZNF12 ZNF316 C7orf26 COL28A1 RPA3 LOC100421597 CCZ1B
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around C7orf26 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the C7orf26 gene promoter:

Genomic Locations for C7orf26 Gene

Genomic Locations for C7orf26 Gene
19,359 bases
Plus strand

Genomic View for C7orf26 Gene

Genes around C7orf26 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C7orf26 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C7orf26 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C7orf26 Gene

Proteins for C7orf26 Gene

  • Protein details for C7orf26 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Uncharacterized protein C7orf26
    Protein Accession:
    Secondary Accessions:
    • Q9BQ43

    Protein attributes for C7orf26 Gene

    449 amino acids
    Molecular mass:
    50047 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for C7orf26 Gene


neXtProt entry for C7orf26 Gene

Post-translational modifications for C7orf26 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for C7orf26 Gene

Domains & Families for C7orf26 Gene

Gene Families for C7orf26 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for C7orf26 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C7orf26: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C7orf26 Gene

Function for C7orf26 Gene

Phenotypes From GWAS Catalog for C7orf26 Gene

genes like me logo Genes that share phenotypes with C7orf26: view

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C7orf26 Gene

Localization for C7orf26 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for C7orf26 gene
Compartment Confidence
plasma membrane 2
nucleus 2
cytosol 2
peroxisome 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Cytosol (2)
  • Intermediate filaments (2)
  • Nucleoli (2)
  • Nucleus (2)
See all subcellular structures

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C7orf26 Gene

Pathways & Interactions for C7orf26 Gene

SuperPathways for C7orf26 Gene

No Data Available

Gene Ontology (GO) - Biological Process for C7orf26 Gene


No data available for Pathways by source and SIGNOR curated interactions for C7orf26 Gene

Drugs & Compounds for C7orf26 Gene

No Compound Related Data Available

Transcripts for C7orf26 Gene

Unigene Clusters for C7orf26 Gene

Chromosome 7 open reading frame 26:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for C7orf26 Gene

ExUns: 1a · 1b · 1c ^ 2a · 2b · 2c ^ 3a · 3b · 3c ^ 4 ^ 5a · 5b · 5c · 5d · 5e ^ 6 ^ 7a · 7b ^ 8 ^ 9a · 9b ^ 10a · 10b · 10c
SP1: - - - - - - - - - -
SP2: - - - - - -
SP3: - - -
SP4: - - - -
SP5: - - -
SP6: - - -
SP8: -
SP10: - - -

Relevant External Links for C7orf26 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C7orf26 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for C7orf26 Gene

Protein differential expression in normal tissues from HIPED for C7orf26 Gene

This gene is overexpressed in Platelet (49.2) and CD4 Tcells (7.4).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for C7orf26 Gene

Protein tissue co-expression partners for C7orf26 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of C7orf26 Gene:


SOURCE GeneReport for Unigene cluster for C7orf26 Gene:


Evidence on tissue expression from TISSUES for C7orf26 Gene

  • Intestine(3)
  • Pancreas(3)
genes like me logo Genes that share expression patterns with C7orf26: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for C7orf26 Gene

Orthologs for C7orf26 Gene

This gene was present in the common ancestor of animals.

Orthologs for C7orf26 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia C7orf26 34
  • 100 (a)
C7H7orf26 33
  • 99.63 (n)
(Canis familiaris)
Mammalia C7orf26 34
  • 96 (a)
C6H7orf26 33
  • 91.22 (n)
(Bos Taurus)
Mammalia C25H7ORF26 34
  • 93 (a)
C25H7orf26 33
  • 88.52 (n)
(Rattus norvegicus)
Mammalia LOC683674 33
  • 88.47 (n)
(Mus musculus)
Mammalia E130309D02Rik 33 16 34
  • 88.1 (n)
(Monodelphis domestica)
Mammalia C7orf26 34
  • 84 (a)
(Ornithorhynchus anatinus)
Mammalia C7orf26 34
  • 77 (a)
(Gallus gallus)
Aves C7orf26 34
  • 84 (a)
C7ORF26 33
  • 79.36 (n)
(Anolis carolinensis)
Reptilia C7orf26 34
  • 70 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia c7orf26 33
  • 70.11 (n)
Str.18839 33
African clawed frog
(Xenopus laevis)
Amphibia MGC69165 33
(Danio rerio)
Actinopterygii zgc:56409 33
  • 63.78 (n)
C1H7orf26 34
  • 58 (a)
zgc56409 33
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP001655 33
  • 47.51 (n)
fruit fly
(Drosophila melanogaster)
Insecta CG5274 33 34
  • 46.33 (n)
Species where no ortholog for C7orf26 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for C7orf26 Gene

Gene Tree for C7orf26 (if available)
Gene Tree for C7orf26 (if available)

Paralogs for C7orf26 Gene

No data available for Paralogs for C7orf26 Gene

Variants for C7orf26 Gene

Sequence variations from dbSNP and Humsavar for C7orf26 Gene

SNP ID Clin Chr 07 pos Variation AA Info Type
rs1000049522 -- 6,599,365(+) A/C intron_variant
rs1000133121 -- 6,596,493(+) C/G intron_variant
rs1000196336 -- 6,591,045(+) C/G intron_variant
rs1000314922 -- 6,590,875(+) G/A intron_variant
rs1000343281 -- 6,604,291(+) G/A genic_downstream_transcript_variant, intron_variant

Structural Variations from Database of Genomic Variants (DGV) for C7orf26 Gene

Variant ID Type Subtype PubMed ID
dgv1090n67 CNV gain 20364138
dgv11172n54 CNV loss 21841781
dgv11173n54 CNV loss 21841781
esv1914954 OTHER inversion 16254605
esv2733932 CNV deletion 23290073
esv2733933 CNV deletion 23290073
nsv1020236 CNV gain 25217958
nsv436904 CNV insertion 17901297
nsv508444 CNV deletion 20534489
nsv515978 CNV loss 19592680
nsv606003 CNV loss 21841781
nsv7392 OTHER inversion 18451855
nsv830895 CNV loss 17160897
nsv950804 CNV deletion 24416366

Variation tolerance for C7orf26 Gene

Residual Variation Intolerance Score: 18.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.89; 48.57% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for C7orf26 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C7orf26 Gene

Disorders for C7orf26 Gene

Additional Disease Information for C7orf26

No disorders were found for C7orf26 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C7orf26 Gene

Publications for C7orf26 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
  3. Panorama of ancient metazoan macromolecular complexes. (PMID: 26344197) Wan C … Emili A (Nature 2015) 3 58
  4. Interactome study suggests multiple cellular functions of hepatoma-derived growth factor (HDGF). (PMID: 21907836) Zhao J … Yang P (Journal of proteomics 2011) 3 58
  5. Streamlined analysis schema for high-throughput identification of endogenous protein complexes. (PMID: 20133760) Malovannaya A … Qin J (Proceedings of the National Academy of Sciences of the United States of America 2010) 3 58

Products for C7orf26 Gene

Sources for C7orf26 Gene

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