Aliases for C7orf61 Gene

Aliases for C7orf61 Gene

  • Chromosome 7 Open Reading Frame 61 2 3 5
  • Uncharacterized Protein C7orf61 3 4
  • IMAGE:4839025 2
  • C7orf61 5

External Ids for C7orf61 Gene

Previous GeneCards Identifiers for C7orf61 Gene

  • GC07M099893
  • GC07M100054
  • GC07M094687

Summaries for C7orf61 Gene

GeneCards Summary for C7orf61 Gene

C7orf61 (Chromosome 7 Open Reading Frame 61) is a Protein Coding gene.

Additional gene information for C7orf61 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for C7orf61 Gene

Genomics for C7orf61 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for C7orf61 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around C7orf61 on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for C7orf61

Top Transcription factor binding sites by QIAGEN in the C7orf61 gene promoter:
  • ITF-2
  • PPAR-gamma1
  • PPAR-gamma2
  • SRF
  • SRF (504 AA)
  • Tal-1beta
  • YY1

Genomic Locations for C7orf61 Gene

Genomic Locations for C7orf61 Gene
7,641 bases
Minus strand
7,657 bases
Minus strand

Genomic View for C7orf61 Gene

Genes around C7orf61 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C7orf61 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C7orf61 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C7orf61 Gene

Proteins for C7orf61 Gene

  • Protein details for C7orf61 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Uncharacterized protein C7orf61
    Protein Accession:

    Protein attributes for C7orf61 Gene

    206 amino acids
    Molecular mass:
    23862 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C7orf61 Gene

Post-translational modifications for C7orf61 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C7orf61 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C7orf61 Gene

Domains & Families for C7orf61 Gene

Gene Families for C7orf61 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for C7orf61 Gene

genes like me logo Genes that share domains with C7orf61: view

No data available for Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for C7orf61 Gene

Function for C7orf61 Gene

Phenotypes From GWAS Catalog for C7orf61 Gene

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for C7orf61

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for C7orf61 Gene

Localization for C7orf61 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for C7orf61 gene
Compartment Confidence
nucleus 4
mitochondrion 2
golgi apparatus 1

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for C7orf61 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus HDA 21630459
genes like me logo Genes that share ontologies with C7orf61: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for C7orf61 Gene

Pathways & Interactions for C7orf61 Gene

PathCards logo

SuperPathways for C7orf61 Gene

No Data Available

Interacting Proteins for C7orf61 Gene

Gene Ontology (GO) - Biological Process for C7orf61 Gene


No data available for Pathways by source and SIGNOR curated interactions for C7orf61 Gene

Drugs & Compounds for C7orf61 Gene

No Compound Related Data Available

Transcripts for C7orf61 Gene

mRNA/cDNA for C7orf61 Gene

1 NCBI additional mRNA sequence :
2 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for C7orf61

Alternative Splicing Database (ASD) splice patterns (SP) for C7orf61 Gene

No ASD Table

Relevant External Links for C7orf61 Gene

GeneLoc Exon Structure for

Expression for C7orf61 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for C7orf61 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

  • Testis (Reproductive System)

mRNA differential expression in normal tissues according to GTEx for C7orf61 Gene

This gene is overexpressed in Testis (x17.3).

Protein differential expression in normal tissues from HIPED for C7orf61 Gene

This gene is overexpressed in Testis (65.5).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C7orf61 Gene

Protein tissue co-expression partners for C7orf61 Gene

- Elite partner

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for C7orf61

SOURCE GeneReport for Unigene cluster for C7orf61 Gene:


Evidence on tissue expression from TISSUES for C7orf61 Gene

  • Nervous system(3)
genes like me logo Genes that share expression patterns with C7orf61: view

Primer Products

No data available for mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for C7orf61 Gene

Orthologs for C7orf61 Gene

This gene was present in the common ancestor of mammals.

Orthologs for C7orf61 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia C7orf61 31
  • 100 (a)
C7H7orf61 30
  • 99.51 (n)
(Canis familiaris)
Mammalia C6H7orf61 30
  • 77.56 (n)
(Bos Taurus)
Mammalia C25H7orf61 30
  • 75.91 (n)
C7orf61 31
  • 64 (a)
(Rattus norvegicus)
Mammalia LOC100362783 30
  • 62.76 (n)
Species where no ortholog for C7orf61 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Lizard (Anolis carolinensis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Mouse (Mus musculus)
  • Oppossum (Monodelphis domestica)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Platypus (Ornithorhynchus anatinus)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Tropical Clawed Frog (Silurana tropicalis)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)
  • Zebrafish (Danio rerio)

Evolution for C7orf61 Gene

Gene Tree for C7orf61 (if available)
Gene Tree for C7orf61 (if available)

Paralogs for C7orf61 Gene

No data available for Paralogs for C7orf61 Gene

Variants for C7orf61 Gene

Additional dbSNP identifiers (rs#s) for C7orf61 Gene

Structural Variations from Database of Genomic Variants (DGV) for C7orf61 Gene

Variant ID Type Subtype PubMed ID
esv2734888 CNV deletion 23290073
nsv518432 CNV loss 19592680
nsv527050 CNV loss 19592680
nsv527107 CNV loss 19592680
nsv831071 CNV loss 17160897

Variation tolerance for C7orf61 Gene

Residual Variation Intolerance Score: 43.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.46; 9.97% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for C7orf61 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for C7orf61 Gene

Disorders for C7orf61 Gene

No disorders were found for C7orf61 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C7orf61 Gene

Publications for C7orf61 Gene

  1. Human chromosome 7: DNA sequence and biology. (PMID: 12690205) Scherer SW … Tsui LC (Science (New York, N.Y.) 2003) 2 3 4
  2. Estrogen-regulated feedback loop limits the efficacy of estrogen receptor-targeted breast cancer therapy. (PMID: 29987050) Xiao T … Brown M (Proceedings of the National Academy of Sciences of the United States of America 2018) 3
  3. Proteomic characterization of the human sperm nucleus. (PMID: 21630459) de Mateo S … Oliva R (Proteomics 2011) 3
  4. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PMID: 17207965) Lamesch P … Vidal M (Genomics 2007) 3
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 4

Products for C7orf61 Gene

Sources for C7orf61 Gene