Aliases for C6orf99 Gene

Subcategory (RNA class) for C6orf99 Gene

lncRNA

Number of RNA Genes sources:

3 / 14

Aliases for C6orf99 Gene

  • Chromosome 6 Open Reading Frame 99 2 3 5
  • Putative Uncharacterized Protein C6orf99 4
  • NONHSAG045268 92
  • HSALNG0054703 167
  • Lnc-SYTL3-2 168

External Ids for C6orf99 Gene

Previous GeneCards Identifiers for C6orf99 Gene

  • GC00U914191
  • GC06U900640
  • GC06P159211
  • GC06P159290
  • GC06P156780

Summaries for C6orf99 Gene

GeneCards Summary for C6orf99 Gene

C6orf99 (Chromosome 6 Open Reading Frame 99) is an RNA Gene, and is affiliated with the lncRNA class.

Additional gene information for C6orf99 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for C6orf99 Gene

Genomics for C6orf99 Gene

GeneHancer (GH) Regulatory Elements for C6orf99 Gene

Promoters and enhancers for C6orf99 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH06J158866 Promoter/Enhancer 1.9 Ensembl ENCODE CraniofacialAtlas dbSUPER 500.7 -0.9 -915 4.6 ZBTB40 CTCF ZSCAN5C NRF1 TCF12 SP1 JUND FOS ZFX ZNF639 C6orf99 lnc-EZR-4 EZR OSTCP1 lnc-EZR-1 RF00017-5918
GH06J158998 Promoter/Enhancer 2.4 EPDnew Ensembl ENCODE CraniofacialAtlas 4.6 +130.8 130786 6.8 FOXK2 ZBTB40 ZNF217 EP300 CTCF ZSCAN5C SIN3A NRF1 MYC USF1 RSPH3 lnc-FNDC1-10-001 WTAP C6orf99 LOC105378083
GH06J158923 Enhancer 0.9 Ensembl ENCODE 10.2 +54.5 54487 1.8 HNRNPK ZNF639 ZIC2 AFF1 TRIM28 MEF2A OSR2 PCBP1 KLF9 WT1 C6orf99 RSPH3 ENSG00000213076 LOC442272 RNU6-293P RF00026-983
GH06J158917 Enhancer 1 Ensembl ENCODE 9.1 +47.8 47787 1.6 TRIM28 CTBP1 TEAD1 ATF2 NFIC ZBTB17 ZNF184 TRIM24 CEBPG MAX C6orf99 SYNJ2-IT1 ENSG00000213076 LOC442272 piR-56037-043
GH06J158920 Enhancer 0.9 Ensembl ENCODE 9.3 +51.0 50987 1.6 ZBTB5 TEAD1 RELA CEBPB ZNF316 CEBPG ZNF592 ZNF395 ZNF384 NFE2 ENSG00000213076 LOC442272 C6orf99 RSPH3 piR-56037-043
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around C6orf99 on UCSC Golden Path with GeneCards custom track

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for C6orf99

Genomic Locations for C6orf99 Gene

Genomic Locations for C6orf99 Gene
chr6:158,869,814-158,919,105
(GRCh38/hg38)
Size:
49,292 bases
Orientation:
Plus strand
chr6:159,290,971-159,331,385
(GRCh37/hg19)
Size:
40,415 bases
Orientation:
Plus strand

Genomic View for C6orf99 Gene

Genes around C6orf99 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C6orf99 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C6orf99 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C6orf99 Gene

Proteins for C6orf99 Gene

  • Protein details for C6orf99 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q4VX62-CF099_HUMAN
    Recommended name:
    Putative uncharacterized protein C6orf99
    Protein Accession:
    Q4VX62
    Secondary Accessions:
    • Q4VX61

    Protein attributes for C6orf99 Gene

    Size:
    202 amino acids
    Molecular mass:
    22766 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for C6orf99 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for C6orf99 Gene

Post-translational modifications for C6orf99 Gene

No Post-translational modifications

No data available for DME Specific Peptides for C6orf99 Gene

Domains & Families for C6orf99 Gene

Protein Domains for C6orf99 Gene

ProtoNet:
genes like me logo Genes that share domains with C6orf99: view

No data available for Gene Families , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for C6orf99 Gene

Function for C6orf99 Gene

Phenotypes From GWAS Catalog for C6orf99 Gene

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for C6orf99 Gene

Localization for C6orf99 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for C6orf99 gene
Compartment Confidence
extracellular 2
peroxisome 1
nucleus 1
cytosol 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for C6orf99 Gene

Pathways & Interactions for C6orf99 Gene

PathCards logo

SuperPathways for C6orf99 Gene

No Data Available
;

Gene Ontology (GO) - Biological Process for C6orf99 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for C6orf99 Gene

Drugs & Compounds for C6orf99 Gene

No Compound Related Data Available

Transcripts for C6orf99 Gene

mRNA/cDNA for C6orf99 Gene

28 RNACentral transcripts :
14 REFSEQ mRNAs :
9 NCBI additional mRNA sequence :
15 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
5 NONCODE transcripts :
1 LncBook transcripts :
5 LNCipedia transcripts :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for C6orf99 Gene

No ASD Table

Relevant External Links for C6orf99 Gene

GeneLoc Exon Structure for
C6orf99

Expression for C6orf99 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for C6orf99 Gene

mRNA differential expression in normal tissues according to GTEx for C6orf99 Gene

This gene is overexpressed in Testis (x45.8).

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for C6orf99

SOURCE GeneReport for Unigene cluster for C6orf99 Gene:

Hs.32804
genes like me logo Genes that share expression patterns with C6orf99: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for C6orf99 Gene

Orthologs for C6orf99 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for C6orf99 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C6H6orf99 30
  • 96.94 (n)
C6orf99 31
  • 57 (a)
OneToOne
Species where no ortholog for C6orf99 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C6orf99 Gene

ENSEMBL:
Gene Tree for C6orf99 (if available)
TreeFam:
Gene Tree for C6orf99 (if available)

Paralogs for C6orf99 Gene

No data available for Paralogs for C6orf99 Gene

Variants for C6orf99 Gene

Additional dbSNP identifiers (rs#s) for C6orf99 Gene

Structural Variations from Database of Genomic Variants (DGV) for C6orf99 Gene

Variant ID Type Subtype PubMed ID
dgv1073n67 CNV loss 20364138
dgv1074n67 CNV loss 20364138
esv2677655 CNV deletion 23128226
esv2733019 CNV deletion 23290073
esv3611406 CNV loss 21293372
esv3611407 CNV loss 21293372
nsv442017 CNV gain+loss 18776908
nsv527528 CNV loss 19592680

Variation tolerance for C6orf99 Gene

Gene Damage Index Score: 0.58; 12.52% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for C6orf99 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
C6orf99

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for C6orf99 Gene

Disorders for C6orf99 Gene

Additional Disease Information for C6orf99

No disorders were found for C6orf99 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C6orf99 Gene

Publications for C6orf99 Gene

  1. The DNA sequence and analysis of human chromosome 6. (PMID: 14574404) Mungall AJ … Beck S (Nature 2003) 3 4 54
  2. E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins. (PMID: 29676528) Khanna R … Parnaik VK (The FEBS journal 2018) 3 54
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K … Sugano S (Genome research 2006) 3 54

Products for C6orf99 Gene

Sources for C6orf99 Gene