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Aliases for C6orf62 Gene
Aliases for C6orf62 Gene
External Ids for C6orf62 Gene
- HGNC: 20998
- Entrez Gene: 81688
- Ensembl: ENSG00000112308
- UniProtKB: Q9GZU0
Previous GeneCards Identifiers for C6orf62 Gene
- GC06M024767
- GC06M024813
- GC06M024705
- GC06M024654
Summaries for C6orf62 Gene
GeneCards Summary for C6orf62 Gene
C6orf62 (Chromosome 6 Open Reading Frame 62) is a Protein Coding gene. Diseases associated with C6orf62 include Succinic Semialdehyde Dehydrogenase Deficiency and Gamma-Amino Butyric Acid Metabolism Disorder.
Additional gene information for C6orf62 Gene
- HGNC(20998)
- Entrez Gene(81688)
- Ensembl(ENSG00000112308)
- UniProtKB(Q9GZU0)
- Open Targets Platform(ENSG00000112308)
- Search for C6orf62 at DataMed
- Search for C6orf62 at HumanCyc
No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for C6orf62 Gene
Genomics for C6orf62 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for C6orf62 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around C6orf62 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for C6orf62
- Top Transcription factor binding sites by QIAGEN in the C6orf62 gene promoter:
-
- AML1a
- AP-2gamma
- ARP-1
- ATF-2
- CRE-BP1
- En-1
- Gfi-1
- HNF-1A
- POU2F1a
- Sp1
Genomic Locations for C6orf62 Gene
Genomic Locations for C6orf62 Gene
- chr6:24,704,299-24,720,920
- (GRCh38/hg38)
- Size:
- 16,622 bases
- Orientation:
- Minus strand
- chr6:24,705,089-24,721,064
- (GRCh37/hg19)
- Size:
- 15,976 bases
- Orientation:
- Minus strand
Genomic View for C6orf62 Gene
Genes around C6orf62 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 6p22.3 by HGNC
- 6p22.3 by Entrez Gene
- 6p22.3 by Ensembl
C6orf62 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for C6orf62 Gene
Proteins for C6orf62 Gene
-
Protein details for C6orf62 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9GZU0-CF062_HUMAN
- Recommended name:
- Uncharacterized protein C6orf62
- Protein Accession:
- Q9GZU0
- Q3LIB6
- Q5JVZ2
- Q5JVZ3
- Q6IA63
- Q9H1Z2
Protein attributes for C6orf62 Gene
- Size:
- 229 amino acids
- Molecular mass:
- 27083 Da
- Quaternary structure:
- No Data Available
Protein Expression for C6orf62 Gene
Post-translational modifications for C6orf62 Gene
Other Protein References for C6orf62 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for C6orf62
- Novus Biologicals Antibodies for C6orf62
-
Abcam antibodies for C6orf62
- Invitrogen Antibodies for C6orf62 (AFLGC-C6orf62)
- antibodies-online: Show 8 available C6ORF62 Antibodies ranked by validation data
-
Biorbyt antibodies for C6orf62
- Sino Biological Antibodies for C6orf62
Protein Products
-
OriGene Purified Proteins for C6orf62
- Search Origene for MassSpec and Protein Over-expression Lysates for C6orf62
- Origene Custom Protein Services for C6orf62
No data available for DME Specific Peptides for C6orf62 Gene
Domains & Families for C6orf62 Gene
Gene Families for C6orf62 Gene
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Suggested Antigen Peptide Sequences for C6orf62 Gene
- GenScript: Design optimal peptide antigens:
-
- cDNA FLJ52139 (B4DWX7_HUMAN)
- HBV XAg-transactivated protein 12 (CF062_HUMAN)
No data available for Graphical View of Domain Structure and UniProtKB/Swiss-Prot for C6orf62 Gene
Function for C6orf62 Gene
Phenotypes From GWAS Catalog for C6orf62 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003674 | molecular_function | ND | -- |
Phenotypes for C6orf62 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for C6orf62 - Select products 50% OFF >
- * C6orf62 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for C6orf62
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for C6orf62
-
Santa Cruz Biotechnology (SCBT) CRISPR for C6orf62
miRNA for C6orf62 Gene
- miRTarBase miRNAs that target C6orf62
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for C6orf62
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Clone Products
- Applied Biological Materials (abm): Clones for C6orf62 - Select products 50% OFF >
- * C6orf62 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for C6orf62
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Cell Line Products
-
Horizon Cell Lines for C6orf62
No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C6orf62 Gene
Localization for C6orf62 Gene
| Compartment | Confidence |
|---|---|
| nucleus | 2 |
| cytosol | 2 |
- Cytosol (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005622 | intracellular | IDA | -- |
No data available for Subcellular locations from UniProtKB/Swiss-Prot for C6orf62 Gene
Pathways & Interactions for C6orf62 Gene
Interacting Proteins for C6orf62 Gene
GPS-Prot Interaction Network for C6orf62
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0008150 | biological_process | ND | -- |
No data available for Pathways by source and SIGNOR curated interactions for C6orf62 Gene
Transcripts for C6orf62 Gene
mRNA/cDNA for C6orf62 Gene
- 1 REFSEQ mRNAs :
- 10 NCBI additional mRNA sequence :
- 2 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000378119 2452 nts (view in UCSC)
- ENST00000378102 741 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for C6orf62 - Select products 50% OFF >
- * C6orf62 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for C6orf62
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for C6orf62
-
Santa Cruz Biotechnology (SCBT) CRISPR for C6orf62
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for C6orf62
- Browse OriGene Inhibitory RNA Products For C6orf62
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for C6orf62
Clone Products
- Applied Biological Materials (abm): Clones for C6orf62 - Select products 50% OFF >
- * C6orf62 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for C6orf62
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for C6orf62
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | ^ | 5 | ^ | 6 | ^ | 7a | · | 7b | · | 7c |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | ||||||||||||||||||||||
| SP2: | - | - | - | ||||||||||||||||||||
| SP3: | - | - | |||||||||||||||||||||
| SP4: |
Relevant External Links for C6orf62 Gene
- GeneLoc Exon Structure for
- C6orf62
Expression for C6orf62 Gene
This gene is overexpressed in Bone marrow mesenchymal stem cell (69.0).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C6orf62 Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for C6orf62
SOURCE GeneReport for Unigene cluster for C6orf62 Gene:
Hs.744857Evidence on tissue expression from TISSUES for C6orf62 Gene
- Nervous system(4.6)
- Spleen(2.2)
Primer Products
-
OriGene qPCR primer pairs for C6orf62
-
OriGene qPCR primer pairs and template standards for C6orf62
Gene Expression Assay Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for C6orf62 Gene
Orthologs for C6orf62 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | C6orf62 31 |
|
OneToOne | |
| C6H6orf62 30 |
|
||||
| Dog (Canis familiaris) |
Mammalia | C6orf62 31 |
|
OneToOne | |
| C35H6orf62 30 |
|
||||
| Cow (Bos Taurus) |
Mammalia | C23H6ORF62 31 |
|
OneToOne | |
| C23H6orf62 30 |
|
||||
| Oppossum (Monodelphis domestica) |
Mammalia | C6orf62 31 |
|
OneToOne | |
| Mouse (Mus musculus) |
Mammalia | BC005537 30 17 31 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | C6orf62 31 |
|
OneToOne | |
| Chicken (Gallus gallus) |
Aves | C6orf62 31 |
|
OneToOne | |
| C2H6ORF62 30 |
|
||||
| Lizard (Anolis carolinensis) |
Reptilia | C6orf62 31 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | c6orf62 30 |
|
||
| Str.7520 30 |
|
||||
| African clawed frog (Xenopus laevis) |
Amphibia | Xl.24169 30 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | C19H6orf62 31 |
|
OneToOne | |
| zgc:111986 30 |
|
||||
| wufb59h04 30 |
|
||||
| Sea Squirt (Ciona savignyi) |
Ascidiacea | -- 31 |
|
OneToOne |
- Species where no ortholog for C6orf62 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rat (Rattus norvegicus)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
Paralogs for C6orf62 Gene
No data available for Paralogs for C6orf62 Gene
Variants for C6orf62 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for C6orf62 Gene
| SNP ID | Clinical significance and condition | Chr 06 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs34238213 | - | p.Trp116Cys | |||
| rs35050510 | - | p.Arg140Ser |
Residual Variation Intolerance Score:
30.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.42;
9.28% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for C6orf62 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- C6orf62
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C6orf62 Gene
Disorders for C6orf62 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| succinic semialdehyde dehydrogenase deficiency |
|
|
| gamma-amino butyric acid metabolism disorder |
|
|
Search C6orf62 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for C6orf62
- Genetic Association Database
- (GAD)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
No data available for UniProtKB/Swiss-Prot and Genatlas for C6orf62 Gene
Publications for C6orf62 Gene
- Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PMID: 11230166) Wiemann S … Poustka A (Genome research 2001) 2 3 4
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4
- The DNA sequence and analysis of human chromosome 6. (PMID: 14574404) Mungall AJ … Beck S (Nature 2003) 3 4
- Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3
ExternalLinks
Products for C6orf62 Gene
- Custom Antibody ServicesOriGene Antibodies for C6orf62
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for C6orf62
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- OriGene qPCR primer pairs for C6orf62
- OriGene qPCR primer pairs and template standards for C6orf62
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- Sino Biological Antibodies for C6orf62
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- High-throughput Antibody Production Service
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- Novus Biologicals proteins and lysates for C6orf62
- Browse Antibodies
- Browse Peptides and Proteins
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- Abcam antibodies for C6orf62
- Find your target
- Browse Primary Antibodies
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- Browse Proteins and Peptides
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- Browse Recombinant Antibodies
- Invitrogen Antibodies for C6orf62 (AFLGC-C6orf62)
- VectorBuilder Custom and pre-made DNA vectors for C6orf62 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for C6orf62 (ie. lentivirus, AAV, adenovirus)
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- VectorBuilder Virus packaging for C6orf62 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for C6orf62
- antibodies-online: Show 8 available C6ORF62 Antibodies ranked by validation data
- antibodies-online: Search results for available C6ORF62 related products ranked by validation data
- antibodies-online: Search results for available C6ORF62 related products ranked by validation data
- Horizon Cell Lines for C6orf62
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for C6orf62
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- Biorbyt antibodies for C6orf62
Sources for C6orf62 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB