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Aliases for C6orf203 Gene

Aliases for C6orf203 Gene

  • Chromosome 6 Open Reading Frame 203 2 3 5
  • Uncharacterized Protein C6orf203 3
  • HSPC230 3
  • PRED31 3

External Ids for C6orf203 Gene

Previous GeneCards Identifiers for C6orf203 Gene

  • GC06P107349
  • GC06P107394
  • GC06P107456
  • GC06P104921

Summaries for C6orf203 Gene

GeneCards Summary for C6orf203 Gene

C6orf203 (Chromosome 6 Open Reading Frame 203) is a Protein Coding gene.

Additional gene information for C6orf203 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C6orf203 Gene

Genomics for C6orf203 Gene

GeneHancer (GH) Regulatory Elements for C6orf203 Gene

Promoters and enhancers for C6orf203 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH06J107027 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 658.7 +0.2 217 1.6 HDGF PKNOX1 ARNT ARID4B SIN3A FEZF1 DMAP1 ZNF2 ZBTB7B YY1 C6orf203 RPL3P7 PIR49317
GH06J107060 Enhancer 0.7 Ensembl ENCODE 12.1 +33.4 33353 1.4 SOX13 ZNF316 FOXA2 IKZF1 RUNX3 MAFK C6orf203 PIR49317
GH06J106997 Enhancer 0.7 ENCODE 12 -30.1 -30053 1.9 CTCF IRF2 ZNF792 SAP130 ZNF644 ZNF2 ZNF48 RAD21 ZNF614 SMC3 C6orf203 RTN4IP1 QRSL1 CD24
GH06J107064 Enhancer 0.9 Ensembl ENCODE 0.3 +36.7 36695 0.7 IRF2 RB1 BATF POLR2A EED NR2F6 IKZF2 RUNX3 RXRA NFIA PIR49317 PIR52349 C6orf203 BEND3
GH06J107042 Enhancer 0.6 ENCODE 0.4 +14.5 14480 0.5 PKNOX1 ZNF687 NR2F1 EBF1 DPF2 BATF IKZF1 RCOR1 SPI1 CHD2 C6orf203 PIR49317
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around C6orf203 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the C6orf203 gene promoter:

Genomic Locations for C6orf203 Gene

Genomic Locations for C6orf203 Gene
23,415 bases
Plus strand

Genomic View for C6orf203 Gene

Genes around C6orf203 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C6orf203 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C6orf203 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C6orf203 Gene

Proteins for C6orf203 Gene

  • Protein details for C6orf203 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Uncharacterized protein C6orf203
    Protein Accession:
    Secondary Accessions:
    • B3KRG9

    Protein attributes for C6orf203 Gene

    240 amino acids
    Molecular mass:
    27941 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C6orf203 Gene

Post-translational modifications for C6orf203 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for C6orf203 Gene

Domains & Families for C6orf203 Gene

Gene Families for C6orf203 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for C6orf203 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C6orf203: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C6orf203 Gene

Function for C6orf203 Gene

Phenotypes From GWAS Catalog for C6orf203 Gene

genes like me logo Genes that share phenotypes with C6orf203: view

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for C6orf203 Gene

Localization for C6orf203 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for C6orf203 gene
Compartment Confidence
mitochondrion 5
extracellular 2
peroxisome 1
nucleus 1
endoplasmic reticulum 1
cytosol 1
golgi apparatus 1

Gene Ontology (GO) - Cellular Components for C6orf203 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005739 mitochondrion HDA 20833797
genes like me logo Genes that share ontologies with C6orf203: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from the Human Protein Atlas (HPA) for C6orf203 Gene

Pathways & Interactions for C6orf203 Gene

SuperPathways for C6orf203 Gene

No Data Available

Interacting Proteins for C6orf203 Gene

Selected Interacting proteins: Q9P0P8-CF203_HUMAN for C6orf203 Gene via IID MINT

Gene Ontology (GO) - Biological Process for C6orf203 Gene


No data available for Pathways by source and SIGNOR curated interactions for C6orf203 Gene

Drugs & Compounds for C6orf203 Gene

No Compound Related Data Available

Transcripts for C6orf203 Gene

mRNA/cDNA for C6orf203 Gene

Unigene Clusters for C6orf203 Gene

Chromosome 6 open reading frame 203:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for C6orf203 Gene

No ASD Table

Relevant External Links for C6orf203 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C6orf203 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for C6orf203 Gene

Protein differential expression in normal tissues from HIPED for C6orf203 Gene

This gene is overexpressed in Lung (7.6) and Peripheral blood mononuclear cells (7.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for C6orf203 Gene

Protein tissue co-expression partners for C6orf203 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of C6orf203 Gene:


SOURCE GeneReport for Unigene cluster for C6orf203 Gene:


Evidence on tissue expression from TISSUES for C6orf203 Gene

  • Nervous system(4.3)
  • Liver(4.2)
  • Blood(4.1)
  • Bone marrow(4.1)
genes like me logo Genes that share expression patterns with C6orf203: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for C6orf203 Gene

Orthologs for C6orf203 Gene

This gene was present in the common ancestor of animals.

Orthologs for C6orf203 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia C6orf203 34
  • 100 (a)
C6H6orf203 33
  • 99.45 (n)
(Canis familiaris)
Mammalia C12H6orf203 33
  • 86.19 (n)
C6orf203 34
  • 83 (a)
(Mus musculus)
Mammalia 1700021F05Rik 16 34 33
  • 80.61 (n)
(Rattus norvegicus)
Mammalia LOC683897 33
  • 79.78 (n)
(Monodelphis domestica)
Mammalia C6orf203 34
  • 69 (a)
(Bos Taurus)
Mammalia C9H6ORF203 34
  • 67 (a)
(Ornithorhynchus anatinus)
Mammalia C6orf203 34
  • 53 (a)
(Gallus gallus)
Aves C3H6ORF203 34 33
  • 66.22 (n)
(Anolis carolinensis)
Reptilia C6orf203 34
  • 51 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia c6orf203 33
  • 56.48 (n)
Str.16694 33
African clawed frog
(Xenopus laevis)
Amphibia Xl.19228 33
(Danio rerio)
Actinopterygii C13H6orf203 34
  • 40 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG4884 34
  • 30 (a)
Species where no ortholog for C6orf203 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for C6orf203 Gene

Gene Tree for C6orf203 (if available)
Gene Tree for C6orf203 (if available)

Paralogs for C6orf203 Gene Pseudogenes for C6orf203 Gene

genes like me logo Genes that share paralogs with C6orf203: view

No data available for Paralogs for C6orf203 Gene

Variants for C6orf203 Gene

Sequence variations from dbSNP and Humsavar for C6orf203 Gene

SNP ID Clin Chr 06 pos Variation AA Info Type
rs1000083621 -- 107,050,275(+) G/A intron_variant
rs1000193914 -- 107,043,079(+) C/G intron_variant
rs1000332643 -- 107,038,106(+) T/C intron_variant
rs1000660957 -- 107,032,509(+) G/A intron_variant
rs1001033002 -- 107,048,422(+) G/A intron_variant

Structural Variations from Database of Genomic Variants (DGV) for C6orf203 Gene

Variant ID Type Subtype PubMed ID
dgv6135n100 CNV gain 25217958
dgv87n68 CNV loss 17160897
esv2732546 CNV deletion 23290073
esv3610289 CNV loss 21293372
esv3610290 CNV loss 21293372
nsv508425 CNV deletion 20534489
nsv509145 CNV insertion 20534489
nsv510909 OTHER complex 20534489
nsv5431 CNV insertion 18451855

Variation tolerance for C6orf203 Gene

Residual Variation Intolerance Score: 73.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.15; 23.22% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for C6orf203 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C6orf203 Gene

Disorders for C6orf203 Gene

Additional Disease Information for C6orf203

No disorders were found for C6orf203 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C6orf203 Gene

Publications for C6orf203 Gene

  1. Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PMID: 11042152) Zhang QH … Chen Z (Genome research 2000) 2 3 4 58
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
  4. The DNA sequence and analysis of human chromosome 6. (PMID: 14574404) Mungall AJ … Beck S (Nature 2003) 3 4 58
  5. From PREDs and open reading frames to cDNA isolation: revisiting the human chromosome 21 transcription map. (PMID: 11707072) Reymond A … Antonarakis SE (Genomics 2001) 2 3 58

Products for C6orf203 Gene

Sources for C6orf203 Gene

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