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Aliases for C6orf201 Gene

Aliases for C6orf201 Gene

  • Chromosome 6 Open Reading Frame 201 2 3 5
  • Uncharacterized Protein C6orf201 3
  • Protein MGC87625 3
  • DJ1013A10.5 3

External Ids for C6orf201 Gene

Previous GeneCards Identifiers for C6orf201 Gene

  • GC00U914401
  • GC06U900580
  • GC06P004025
  • GC06P003955

Summaries for C6orf201 Gene

GeneCards Summary for C6orf201 Gene

C6orf201 (Chromosome 6 Open Reading Frame 201) is a Protein Coding gene. Among its related pathways are Mesodermal Commitment Pathway.

Additional gene information for C6orf201 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C6orf201 Gene

Genomics for C6orf201 Gene

GeneHancer (GH) Regulatory Elements for C6orf201 Gene

Promoters and enhancers for C6orf201 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH06I004079 Promoter 0.5 EPDnew 550.8 0.0 -16 0.1 C6orf201 GC06M004077 PSMG4 GC06P004077 FAM217A
GH06I004133 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 27.4 +56.0 56024 3.8 HDGF SMAD1 ZFP64 ARID4B SIN3A DMAP1 ZNF2 YY1 SLC30A9 POLR2B ECI2 ENSG00000254821 LOC100507506 C6orf201 FAM217A GC06P004132
GH06I004017 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 23.6 -58.7 -58680 7 MLX ZFP64 DMAP1 YY1 SLC30A9 ZNF213 E2F8 ZNF416 ZNF143 ZNF548 PRPF4B ENSG00000230648 ENSG00000272248 RIPK1 PSMG4 ENSG00000228170 C6orf201 ENSG00000272320 CDYL FAM50B
GH06I004316 Enhancer 1.7 FANTOM5 Ensembl ENCODE dbSUPER 19.2 +240.8 240836 7.6 PKNOX1 SMAD1 FOXA2 ARNT SIN3A FEZF1 ZNF2 ZNF766 ZNF213 E2F8 PRPF4B CDYL C6orf201 LYRM4-AS1 ENSG00000270504 PIR45023 GC06P004318 LOC101927888
GH06I003156 Promoter/Enhancer 2.8 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 11.3 -917.1 -917098 11.6 DMAP1 YY1 SLC30A9 ZNF213 E2F8 ZNF143 SP3 NFYC SSRP1 ZNF610 TUBB2A TUBB2B TUBB2BP1 PSMG4 PRPF4B C6orf201 RIPK1 BPHL LOC105374889 GC06P003150
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around C6orf201 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the C6orf201 gene promoter:

Genomic Locations for C6orf201 Gene

Genomic Locations for C6orf201 Gene
chr6:4,079,206-4,130,951
(GRCh38/hg38)
Size:
51,746 bases
Orientation:
Plus strand
chr6:4,079,440-4,131,185
(GRCh37/hg19)

Genomic View for C6orf201 Gene

Genes around C6orf201 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C6orf201 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C6orf201 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C6orf201 Gene

Proteins for C6orf201 Gene

  • Protein details for C6orf201 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q7Z4U5-CF201_HUMAN
    Recommended name:
    Uncharacterized protein C6orf201
    Protein Accession:
    Q7Z4U5
    Secondary Accessions:
    • A6NLI6
    • Q6NXN5

    Protein attributes for C6orf201 Gene

    Size:
    140 amino acids
    Molecular mass:
    16243 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for C6orf201 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for C6orf201 Gene

Post-translational modifications for C6orf201 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C6orf201 Gene

No data available for DME Specific Peptides for C6orf201 Gene

Domains & Families for C6orf201 Gene

Gene Families for C6orf201 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for C6orf201 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for C6orf201 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C6orf201: view

No data available for UniProtKB/Swiss-Prot for C6orf201 Gene

Function for C6orf201 Gene

Phenotypes From GWAS Catalog for C6orf201 Gene

genes like me logo Genes that share phenotypes with C6orf201: view

Animal Model Products

CRISPR Products

miRNA for C6orf201 Gene

Inhibitory RNA Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C6orf201 Gene

Localization for C6orf201 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for C6orf201 gene
Compartment Confidence
nucleus 3
cytosol 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for C6orf201 Gene

Pathways & Interactions for C6orf201 Gene

SuperPathways for C6orf201 Gene

SuperPathway Contained pathways
1 Mesodermal Commitment Pathway
genes like me logo Genes that share pathways with C6orf201: view

Pathways by source for C6orf201 Gene

1 BioSystems pathway for C6orf201 Gene

Interacting Proteins for C6orf201 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
http://version10.5.string-db.org/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000420610%0d%0a9606.ENSP00000379901%0d%0a
Selected Interacting proteins: ENSP00000420610 Q7Z4U5-CF201_HUMAN for C6orf201 Gene via STRING IID

Gene Ontology (GO) - Biological Process for C6orf201 Gene

None

No data available for SIGNOR curated interactions for C6orf201 Gene

Drugs & Compounds for C6orf201 Gene

No Compound Related Data Available

Transcripts for C6orf201 Gene

Unigene Clusters for C6orf201 Gene

Chromosome 6 open reading frame 201:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Alternative Splicing Database (ASD) splice patterns (SP) for C6orf201 Gene

ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3 ^ 4a · 4b · 4c ^ 5a · 5b
SP1: -
SP2:
SP3: - - - -
SP4: - -

Relevant External Links for C6orf201 Gene

GeneLoc Exon Structure for
C6orf201
ECgene alternative splicing isoforms for
C6orf201

Expression for C6orf201 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for C6orf201 Gene

mRNA differential expression in normal tissues according to GTEx for C6orf201 Gene

This gene is overexpressed in Testis (x43.5).

Protein differential expression in normal tissues from HIPED for C6orf201 Gene

This gene is overexpressed in Pancreas (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C6orf201 Gene



Protein tissue co-expression partners for C6orf201 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of C6orf201 Gene:

C6orf201

SOURCE GeneReport for Unigene cluster for C6orf201 Gene:

Hs.716731
genes like me logo Genes that share expression patterns with C6orf201: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for C6orf201 Gene

Orthologs for C6orf201 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C6orf201 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C6H6orf201 33
  • 98.33 (n)
C6orf201 34
  • 80 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C35H6orf201 33
  • 77.89 (n)
C6orf201 34
  • 17 (a)
OneToOne
cow
(Bos Taurus)
Mammalia C23H6orf201 33
  • 66.67 (n)
C6orf201 34
  • 33 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia RGD1307537 33
  • 66.17 (n)
mouse
(Mus musculus)
Mammalia 4933417A18Rik 33 16 34
  • 64.51 (n)
oppossum
(Monodelphis domestica)
Mammalia C6orf201 34
  • 18 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia C6orf201 34
  • 18 (a)
OneToOne
Species where no ortholog for C6orf201 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C6orf201 Gene

ENSEMBL:
Gene Tree for C6orf201 (if available)
TreeFam:
Gene Tree for C6orf201 (if available)

Paralogs for C6orf201 Gene

No data available for Paralogs for C6orf201 Gene

Variants for C6orf201 Gene

Sequence variations from dbSNP and Humsavar for C6orf201 Gene

SNP ID Clin Chr 06 pos Variation AA Info Type
rs1000085707 -- 4,078,013(+) T/C upstream_transcript_variant
rs1000086065 -- 4,101,237(+) A/G intron_variant
rs1000217623 -- 4,110,985(+) A/G genic_downstream_transcript_variant, intron_variant
rs1000273393 -- 4,099,638(+) C/T intron_variant
rs1000428451 -- 4,084,728(+) T/C genic_upstream_transcript_variant, intron_variant

Structural Variations from Database of Genomic Variants (DGV) for C6orf201 Gene

Variant ID Type Subtype PubMed ID
esv2422231 CNV deletion 17116639
esv2422457 CNV deletion 17116639
esv3570734 CNV loss 25503493
nsv1140599 CNV deletion 24896259
nsv600860 CNV loss 21841781

Variation tolerance for C6orf201 Gene

Residual Variation Intolerance Score: 90.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 7.24; 81.14% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for C6orf201 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
C6orf201

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C6orf201 Gene

Disorders for C6orf201 Gene

Additional Disease Information for C6orf201

No disorders were found for C6orf201 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C6orf201 Gene

Publications for C6orf201 Gene

  1. Protein array based interactome analysis of amyloid-β indicates an inhibition of protein translation. (PMID: 21244100) Virok DP … Fülöp L (Journal of proteome research 2011) 3 58
  2. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PMID: 21832049) Oláh J … Ovádi J (The Journal of biological chemistry 2011) 3 58
  3. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PMID: 17207965) Lamesch P … Vidal M (Genomics 2007) 3 58
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 4 58
  5. The DNA sequence and analysis of human chromosome 6. (PMID: 14574404) Mungall AJ … Beck S (Nature 2003) 4 58

Products for C6orf201 Gene

Sources for C6orf201 Gene

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