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Aliases for C6orf163 Gene

Aliases for C6orf163 Gene

  • Chromosome 6 Open Reading Frame 163 2 3 5

External Ids for C6orf163 Gene

Previous GeneCards Identifiers for C6orf163 Gene

  • GC06P088007
  • GC06P088061
  • GC06P088052
  • GC06P088114
  • GC06P088115
  • GC06P088054
  • GC06P085271
  • GC06P087344

Summaries for C6orf163 Gene

GeneCards Summary for C6orf163 Gene

C6orf163 (Chromosome 6 Open Reading Frame 163) is a Protein Coding gene.

Additional gene information for C6orf163 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C6orf163 Gene

Genomics for C6orf163 Gene

GeneHancer (GH) Regulatory Elements for C6orf163 Gene

Promoters and enhancers for C6orf163 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH06I087344 Promoter 0.6 EPDnew 550.8 +1.7 1719 0.1 RFX1 C6orf163 ENSG00000279616 LINC01590 SMIM8
GH06I087587 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 12.9 +246.6 246608 3.6 HDGF PKNOX1 MLX ARNT ARID4B SIN3A DMAP1 ZNF2 YY1 SLC30A9 RARS2 ORC3 GC06P087588 SLC35A1 C6orf163 ZNF292
GH06I087151 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 10 -188.7 -188680 6.4 CLOCK MLX ZFP64 FEZF1 DMAP1 YY1 SLC30A9 ZNF213 E2F8 ZNF416 ZNF292 ENSG00000272008 RARS2 SLC35A1 LINC01590 ORC3 SMIM8 CGA C6orf163
GH06I087472 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 10.4 +130.1 130102 2.1 PKNOX1 FOXA2 ARNT ARID4B SIN3A FEZF1 DMAP1 ZNF2 ZBTB7B IRF4 SLC35A1 RARS2 ZNF292 ENSG00000272008 ORC3 C6orf163 GC06P087489 ENSG00000213204
GH06I087722 Enhancer 1.7 FANTOM5 Ensembl ENCODE dbSUPER 5.6 +381.2 381213 4.3 PKNOX1 CLOCK FOXA2 ARNT ARID4B SIN3A DMAP1 IRF4 YY1 ZNF766 ZNF292 AKIRIN2 C6orf163 SLC35A1 SMIM8 RARS2 LINC01590 ENSG00000238628 GC06P087742
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around C6orf163 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the C6orf163 gene promoter:

Genomic Locations for C6orf163 Gene

Genomic Locations for C6orf163 Gene
chr6:87,343,080-87,365,553
(GRCh38/hg38)
Size:
22,474 bases
Orientation:
Plus strand
chr6:88,054,567-88,075,181
(GRCh37/hg19)

Genomic View for C6orf163 Gene

Genes around C6orf163 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C6orf163 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C6orf163 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C6orf163 Gene

Proteins for C6orf163 Gene

  • Protein details for C6orf163 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5TEZ5-CF163_HUMAN
    Recommended name:
    Uncharacterized protein C6orf163
    Protein Accession:
    Q5TEZ5

    Protein attributes for C6orf163 Gene

    Size:
    329 amino acids
    Molecular mass:
    38553 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=CAB71116.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

neXtProt entry for C6orf163 Gene

Post-translational modifications for C6orf163 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C6orf163 Gene

No data available for DME Specific Peptides for C6orf163 Gene

Domains & Families for C6orf163 Gene

Gene Families for C6orf163 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for C6orf163 Gene

ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C6orf163: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C6orf163 Gene

Function for C6orf163 Gene

Phenotypes From GWAS Catalog for C6orf163 Gene

Gene Ontology (GO) - Molecular Function for C6orf163 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003674 molecular_function ND --
genes like me logo Genes that share ontologies with C6orf163: view
genes like me logo Genes that share phenotypes with C6orf163: view

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for C6orf163 Gene

Localization for C6orf163 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for C6orf163 gene
Compartment Confidence
cytosol 3
nucleus 2
mitochondrion 1

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for C6orf163 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005575 cellular_component ND --
genes like me logo Genes that share ontologies with C6orf163: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for C6orf163 Gene

Pathways & Interactions for C6orf163 Gene

SuperPathways for C6orf163 Gene

No Data Available

Interacting Proteins for C6orf163 Gene

Gene Ontology (GO) - Biological Process for C6orf163 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008150 biological_process ND --
genes like me logo Genes that share ontologies with C6orf163: view

No data available for Pathways by source and SIGNOR curated interactions for C6orf163 Gene

Drugs & Compounds for C6orf163 Gene

No Compound Related Data Available

Transcripts for C6orf163 Gene

mRNA/cDNA for C6orf163 Gene

(6) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(13) Selected AceView cDNA sequences:
(4) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for C6orf163 Gene

Chromosome 6 open reading frame 163:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for C6orf163 Gene

No ASD Table

Relevant External Links for C6orf163 Gene

GeneLoc Exon Structure for
C6orf163
ECgene alternative splicing isoforms for
C6orf163

Expression for C6orf163 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for C6orf163 Gene

mRNA differential expression in normal tissues according to GTEx for C6orf163 Gene

This gene is overexpressed in Testis (x8.4).

Protein differential expression in normal tissues from HIPED for C6orf163 Gene

This gene is overexpressed in Breast (64.1).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C6orf163 Gene



Protein tissue co-expression partners for C6orf163 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of C6orf163 Gene:

C6orf163

SOURCE GeneReport for Unigene cluster for C6orf163 Gene:

Hs.646309
genes like me logo Genes that share expression patterns with C6orf163: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for C6orf163 Gene

Orthologs for C6orf163 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C6orf163 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C6H6orf163 33
  • 99.39 (n)
C6orf163 34
  • 99 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C12H6orf163 33
  • 87.03 (n)
C6ORF163 34
  • 82 (a)
OneToOne
cow
(Bos Taurus)
Mammalia C9H6orf163 33 34
  • 84.09 (n)
rat
(Rattus norvegicus)
Mammalia RGD1563056 33
  • 79.31 (n)
mouse
(Mus musculus)
Mammalia Gm136 33 16 34
  • 78.15 (n)
platypus
(Ornithorhynchus anatinus)
Mammalia -- 34
  • 50 (a)
OneToMany
-- 34
  • 49 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia C6orf163 34
  • 47 (a)
OneToOne
chicken
(Gallus gallus)
Aves C6ORF163 33
  • 57.26 (n)
C6orf163 34
  • 39 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia C6orf163 34
  • 40 (a)
OneToOne
Species where no ortholog for C6orf163 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C6orf163 Gene

ENSEMBL:
Gene Tree for C6orf163 (if available)
TreeFam:
Gene Tree for C6orf163 (if available)

Paralogs for C6orf163 Gene

No data available for Paralogs for C6orf163 Gene

Variants for C6orf163 Gene

Sequence variations from dbSNP and Humsavar for C6orf163 Gene

SNP ID Clin Chr 06 pos Variation AA Info Type
rs1000627572 -- 87,345,969(+) A/C 5_prime_UTR_variant, genic_upstream_transcript_variant, intron_variant
rs1000900952 -- 87,346,214(+) T/C 5_prime_UTR_variant, genic_upstream_transcript_variant, intron_variant
rs1001008122 -- 87,360,850(+) G/A intron_variant
rs1001165892 -- 87,353,442(+) TT/T genic_upstream_transcript_variant, intron_variant
rs1001186237 -- 87,352,233(+) C/G genic_upstream_transcript_variant, intron_variant

Structural Variations from Database of Genomic Variants (DGV) for C6orf163 Gene

Variant ID Type Subtype PubMed ID
nsv830722 CNV gain 17160897

Variation tolerance for C6orf163 Gene

Gene Damage Index Score: 4.12; 61.24% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for C6orf163 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
C6orf163

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C6orf163 Gene

Disorders for C6orf163 Gene

Additional Disease Information for C6orf163

No disorders were found for C6orf163 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C6orf163 Gene

Publications for C6orf163 Gene

  1. The DNA sequence and analysis of human chromosome 6. (PMID: 14574404) Mungall AJ … Beck S (Nature 2003) 3 4 58
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 58
  3. FBXL13 directs the proteolysis of CEP192 to regulate centrosome homeostasis and cell migration. (PMID: 29348145) Fung E … D'Angiolella V (EMBO reports 2018) 3

Products for C6orf163 Gene

Sources for C6orf163 Gene

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