Aliases for C5orf66-AS1 Gene

Subcategory (RNA class) for C5orf66-AS1 Gene

lncRNA

Number of RNA Genes sources:

3 / 14

Aliases for C5orf66-AS1 Gene

  • C5orf66 Antisense RNA 1 2 3 5
  • Esophagus Epithelial Intergenic Specific Transcript 2 3
  • C5orf66-AS1 2 168
  • NONHSAG041602 92
  • HSALNG0045015 167
  • Epist 3

External Ids for C5orf66-AS1 Gene

Previous GeneCards Identifiers for C5orf66-AS1 Gene

  • GC05M134375

Summaries for C5orf66-AS1 Gene

GeneCards Summary for C5orf66-AS1 Gene

C5orf66-AS1 (C5orf66 Antisense RNA 1) is an RNA Gene, and is affiliated with the lncRNA class. Diseases associated with C5orf66-AS1 include Gastric Cardia Adenocarcinoma and Squamous Cell Carcinoma.

Additional gene information for C5orf66-AS1 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for C5orf66-AS1 Gene

Genomics for C5orf66-AS1 Gene

GeneHancer (GH) Regulatory Elements for C5orf66-AS1 Gene

Promoters and enhancers for C5orf66-AS1 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around C5orf66-AS1 on UCSC Golden Path with GeneCards custom track

Genomic Locations for C5orf66-AS1 Gene

Genomic Locations for C5orf66-AS1 Gene
chr5:135,038,830-135,040,048
(GRCh38/hg38)
Size:
1,219 bases
Orientation:
Minus strand
chr5:134,374,528-134,375,737
(GRCh37/hg19)
Size:
1,210 bases
Orientation:
Minus strand

Genomic View for C5orf66-AS1 Gene

Genes around C5orf66-AS1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C5orf66-AS1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C5orf66-AS1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C5orf66-AS1 Gene

Proteins for C5orf66-AS1 Gene

Post-translational modifications for C5orf66-AS1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for C5orf66-AS1 Gene

Domains & Families for C5orf66-AS1 Gene

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for C5orf66-AS1 Gene

Function for C5orf66-AS1 Gene

Phenotypes From GWAS Catalog for C5orf66-AS1 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for C5orf66-AS1 Gene

Localization for C5orf66-AS1 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for C5orf66-AS1 gene
Compartment Confidence
nucleus 1
cytosol 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for C5orf66-AS1 Gene

Pathways & Interactions for C5orf66-AS1 Gene

PathCards logo

SuperPathways for C5orf66-AS1 Gene

No Data Available
;

Gene Ontology (GO) - Biological Process for C5orf66-AS1 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for C5orf66-AS1 Gene

Drugs & Compounds for C5orf66-AS1 Gene

No Compound Related Data Available

Transcripts for C5orf66-AS1 Gene

mRNA/cDNA for C5orf66-AS1 Gene

6 RNACentral transcripts :
2 REFSEQ mRNAs :
3 NCBI additional mRNA sequence :
2 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
3 NONCODE transcripts :
2 LncBook transcripts :
4 LNCipedia transcripts :

Alternative Splicing Database (ASD) splice patterns (SP) for C5orf66-AS1 Gene

No ASD Table

Relevant External Links for C5orf66-AS1 Gene

GeneLoc Exon Structure for
C5orf66-AS1

Expression for C5orf66-AS1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for C5orf66-AS1 Gene

mRNA differential expression in normal tissues according to GTEx for C5orf66-AS1 Gene

This gene is overexpressed in Esophagus - Mucosa (x19.2), Pituitary (x8.3), Minor Salivary Gland (x6.3), and Vagina (x6.3).

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for C5orf66-AS1

genes like me logo Genes that share expression patterns with C5orf66-AS1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for C5orf66-AS1 Gene

Orthologs for C5orf66-AS1 Gene

Evolution for C5orf66-AS1 Gene

ENSEMBL:
Gene Tree for C5orf66-AS1 (if available)
TreeFam:
Gene Tree for C5orf66-AS1 (if available)

No data available for Orthologs for C5orf66-AS1 Gene

Paralogs for C5orf66-AS1 Gene

No data available for Paralogs for C5orf66-AS1 Gene

Variants for C5orf66-AS1 Gene

Additional dbSNP identifiers (rs#s) for C5orf66-AS1 Gene

Structural Variations from Database of Genomic Variants (DGV) for C5orf66-AS1 Gene

Variant ID Type Subtype PubMed ID
dgv969n67 CNV gain 20364138
nsv462458 CNV loss 19166990
nsv599744 CNV loss 21841781
nsv823239 CNV gain 20364138
nsv823240 CNV gain 20364138
nsv830495 CNV loss 17160897

Additional Variant Information for C5orf66-AS1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
C5orf66-AS1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for C5orf66-AS1 Gene

Disorders for C5orf66-AS1 Gene

MalaCards: The human disease database

(7) MalaCards diseases for C5orf66-AS1 Gene - From: LncRNADisease and DISEASES

Disorder Aliases PubMed IDs
gastric cardia adenocarcinoma
  • adenocarcinoma of cardia of stomach
squamous cell carcinoma
  • epidermoid carcinoma
squamous cell carcinoma, head and neck
  • hnscc
bladder cancer
  • bladder cancer, somatic
esophageal cancer
  • esophageal cancer, somatic
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for C5orf66-AS1

genes like me logo Genes that share disorders with C5orf66-AS1: view

No data available for UniProtKB/Swiss-Prot and Genatlas for C5orf66-AS1 Gene

Publications for C5orf66-AS1 Gene

  1. Transcriptome profiling of esophageal squamous cell carcinoma reveals a long noncoding RNA acting as a tumor suppressor. (PMID: 26158411) Wei G … Chen R (Oncotarget 2015) 2 3 54
  2. Long non-coding RNA C5orf66-AS1 promotes cell proliferation in cervical cancer by targeting miR-637/RING1 axis. (PMID: 30518760) Rui X … Jiang J (Cell death & disease 2018) 3 54
  3. Aberrant methylation-mediated silencing of lncRNA CTC-276P9.1 is associated with malignant progression of esophageal squamous cell carcinoma. (PMID: 29524086) Guo W … Shan B (Clinical & experimental metastasis 2018) 3 54
  4. Long non-coding RNA C5orf66-AS1 is downregulated in pituitary null cell adenomas and is associated with their invasiveness. (PMID: 28656268) Yu G … Zhang Y (Oncology reports 2017) 3 54
  5. Genomic annotation of 15,809 ESTs identified from pooled early gestation human eyes. (PMID: 16368877) Choy KW … Pang CP (Physiological genomics 2006) 3 54

Products for C5orf66-AS1 Gene

Sources for C5orf66-AS1 Gene