Free for academic non-profit institutions. Other users need a Commercial license
Aliases for C4orf36 Gene
Aliases for C4orf36 Gene
External Ids for C4orf36 Gene
- HGNC: 28386
- Entrez Gene: 132989
- Ensembl: ENSG00000163633
- UniProtKB: Q96KX1
Previous GeneCards Identifiers for C4orf36 Gene
- GC04M088016
- GC04M087797
- GC04M083543
Summaries for C4orf36 Gene
GeneCards Summary for C4orf36 Gene
C4orf36 (Chromosome 4 Open Reading Frame 36) is a Protein Coding gene. An important paralog of this gene is ENSG00000285458.
Additional gene information for C4orf36 Gene
No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for C4orf36 Gene
Genomics for C4orf36 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for C4orf36 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around C4orf36 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for C4orf36
- Top Transcription factor binding sites by QIAGEN in the C4orf36 gene promoter:
-
- Chx10
- CUTL1
- E4BP4
- p53
- POU2F1
- POU2F1a
- S8
- YY1
Genomic Locations for C4orf36 Gene
Genomic Locations for C4orf36 Gene
- chr4:86,876,205-86,897,256
- (GRCh38/hg38)
- Size:
- 21,052 bases
- Orientation:
- Minus strand
- chr4:87,797,358-87,857,354
- (GRCh37/hg19)
- Size:
- 59,997 bases
- Orientation:
- Minus strand
Genomic View for C4orf36 Gene
Genes around C4orf36 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 4q21.3 by HGNC
- 4q21.3 by Entrez Gene
- 4q21.3 by Ensembl
C4orf36 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for C4orf36 Gene
Proteins for C4orf36 Gene
-
Protein details for C4orf36 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q96KX1-CD036_HUMAN
- Recommended name:
- Uncharacterized protein C4orf36
- Protein Accession:
- Q96KX1
Protein attributes for C4orf36 Gene
- Size:
- 117 amino acids
- Molecular mass:
- 13276 Da
- Quaternary structure:
- No Data Available
Protein Expression for C4orf36 Gene
Post-translational modifications for C4orf36 Gene
Other Protein References for C4orf36 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for C4orf36
- Invitrogen Antibodies for C4orf36 (AFLGC-C4orf36)
- antibodies-online: Show 4 available C4ORF36 Antibodies ranked by validation data
Protein Products
-
OriGene Purified Proteins for C4orf36
- Search Origene for MassSpec and Protein Over-expression Lysates for C4orf36
- Origene Custom Protein Services for C4orf36
No data available for DME Specific Peptides for C4orf36 Gene
Domains & Families for C4orf36 Gene
Gene Families for C4orf36 Gene
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
No data available for Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for C4orf36 Gene
Function for C4orf36 Gene
Phenotypes From GWAS Catalog for C4orf36 Gene
Phenotypes for C4orf36 Gene
- MGI mutant phenotypes for C4orf36:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for C4orf36:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for C4orf36 - Select products 50% OFF >
- * C4orf36 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for C4orf36
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for C4orf36
-
Santa Cruz Biotechnology (SCBT) CRISPR for C4orf36
miRNA for C4orf36 Gene
- miRTarBase miRNAs that target C4orf36
-
- hsa-miR-3674 (MIRT526467)
- hsa-miR-135b-3p (MIRT526468)
- hsa-miR-7156-3p (MIRT526469)
- hsa-miR-6516-3p (MIRT526470)
- hsa-miR-1206 (MIRT526471)
- hsa-miR-3121-5p (MIRT526472)
- hsa-miR-7845-5p (MIRT526473)
- hsa-miR-5692a (MIRT526474)
- hsa-miR-1238-3p (MIRT669244)
- hsa-miR-670-3p (MIRT669245)
- hsa-miR-3591-5p (MIRT669246)
- hsa-miR-6881-3p (MIRT669247)
- hsa-miR-6780a-3p (MIRT669248)
- hsa-miR-7111-3p (MIRT669249)
- hsa-miR-4473 (MIRT669250)
- hsa-miR-4671-3p (MIRT669251)
- hsa-miR-3185 (MIRT669252)
- hsa-miR-4778-3p (MIRT669253)
- hsa-miR-877-3p (MIRT669254)
- hsa-miR-513c-3p (MIRT669255)
- hsa-miR-513a-3p (MIRT669256)
- hsa-miR-3606-3p (MIRT669257)
- hsa-miR-301a-3p (MIRT669258)
- hsa-miR-130a-3p (MIRT669259)
- hsa-miR-130b-3p (MIRT669260)
- hsa-miR-301b-3p (MIRT669261)
- hsa-miR-3666 (MIRT669262)
- hsa-miR-4295 (MIRT669263)
- hsa-miR-454-3p (MIRT669264)
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for C4orf36
- Browse OriGene Inhibitory RNA Products For C4orf36
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for C4orf36
Clone Products
- Applied Biological Materials (abm): Clones for C4orf36 - Select products 50% OFF >
- * C4orf36 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for C4orf36
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for C4orf36
Cell Line Products
-
Horizon Cell Lines for C4orf36
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C4orf36 Gene
Localization for C4orf36 Gene
| Compartment | Confidence |
|---|---|
| extracellular | 1 |
| mitochondrion | 1 |
| nucleus | 0 |
| cytosol | 0 |
- Focal adhesion sites (2)
No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C4orf36 Gene
Transcripts for C4orf36 Gene
mRNA/cDNA for C4orf36 Gene
- 3 REFSEQ mRNAs :
- 4 NCBI additional mRNA sequence :
- 6 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000295898 908 nts (view in UCSC)
- ENST00000462714 1610 nts (view in UCSC)
- ENST00000506308 766 nts (view in UCSC)
- ENST00000512468 564 nts (view in UCSC)
- ENST00000504008 448 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for C4orf36 - Select products 50% OFF >
- * C4orf36 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for C4orf36
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for C4orf36
-
Santa Cruz Biotechnology (SCBT) CRISPR for C4orf36
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for C4orf36
- Browse OriGene Inhibitory RNA Products For C4orf36
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for C4orf36
Clone Products
- Applied Biological Materials (abm): Clones for C4orf36 - Select products 50% OFF >
- * C4orf36 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for C4orf36
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for C4orf36
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2a | · | 2b | ^ | 3a | · | 3b | ^ | 4a | · | 4b | · | 4c | ^ | 5a | · | 5b | ^ | 6 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | ||||||||||||||||||||||
| SP2: | - | ||||||||||||||||||||||||
| SP3: | - | - | - | ||||||||||||||||||||||
| SP4: | - | - |
Relevant External Links for C4orf36 Gene
- GeneLoc Exon Structure for
- C4orf36
Expression for C4orf36 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Testis (Reproductive System)
This gene is overexpressed in Uterus (8.3), Spleen (6.7), and Retina (6.1).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C4orf36 Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for C4orf36
SOURCE GeneReport for Unigene cluster for C4orf36 Gene:
Hs.339646Primer Products
-
OriGene qPCR primer pairs for C4orf36
-
OriGene qPCR primer pairs and template standards for C4orf36
Gene Expression Assay Products
No data available for mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for C4orf36 Gene
Orthologs for C4orf36 Gene
This gene was present in the common ancestor of mammals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | C4orf36 31 |
|
OneToOne | |
| C4H4orf36 30 |
|
||||
| Cow (Bos Taurus) |
Mammalia | C6H4orf36 30 |
|
||
| Dog (Canis familiaris) |
Mammalia | C4orf36 31 |
|
OneToOne | |
| Mouse (Mus musculus) |
Mammalia | 1700016H13Rik 30 17 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | LOC498330 30 |
|
||
| Oppossum (Monodelphis domestica) |
Mammalia | C4orf36 31 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | C4orf36 31 |
|
OneToOne |
- Species where no ortholog for C4orf36 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Lizard (Anolis carolinensis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Tropical Clawed Frog (Silurana tropicalis)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
- Zebrafish (Danio rerio)
Paralogs for C4orf36 Gene
Paralogs for C4orf36 Gene
Variants for C4orf36 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for C4orf36 Gene
| SNP ID | Clinical significance and condition | Chr 04 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs11938345 | - | p.Ser18Asn | |||
| rs1550931 | - | p.Ser36Tyr |
Residual Variation Intolerance Score:
82.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
6.50;
77.61% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for C4orf36 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- C4orf36
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C4orf36 Gene
Disorders for C4orf36 Gene
Additional Disease Information for C4orf36
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No disorders were found for C4orf36 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C4orf36 Gene
Publications for C4orf36 Gene
- A high-density genome-wide association screen of sporadic ALS in US veterans. (PMID: 22470424) Kwee LC … Hauser MA (PloS one 2012) 3 41
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose JE … Uhl GR (Molecular medicine (Cambridge, Mass.) 2010) 3 41
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 2 3
- Genetic variants associated with disordered eating. (PMID: 23568457) Wade TD … Martin NG (The International journal of eating disorders 2013) 3
ExternalLinks
Products for C4orf36 Gene
- Custom Antibody ServicesOriGene Antibodies for C4orf36
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for C4orf36
- Search Origene for MassSpec and Protein Over-expression Lysates for C4orf36
- Origene Custom Protein Services for C4orf36
- Origene shrna, sirna, and RNAi products in human, mouse, rat for C4orf36
- Browse OriGene Inhibitory RNA Products For C4orf36
- OriGene qPCR primer pairs for C4orf36
- OriGene qPCR primer pairs and template standards for C4orf36
- OriGene CRISPR knockouts for C4orf36
- OriGene ORF clones in human for C4orf36
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For C4orf36
- Sino Biological Human cDNA Clone for C4orf36
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse cDNA Clones
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for C4orf36
- Novus Biologicals proteins and lysates for C4orf36
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Invitrogen Antibodies for C4orf36 (AFLGC-C4orf36)
- VectorBuilder Custom and pre-made DNA vectors for C4orf36 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for C4orf36 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for C4orf36 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for C4orf36 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for C4orf36
- antibodies-online: Show 4 available C4ORF36 Antibodies ranked by validation data
- antibodies-online: Search results for available C4ORF36 related products ranked by validation data
- antibodies-online: Search results for available C4ORF36 related products ranked by validation data
- Horizon Cell Lines for C4orf36
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for C4orf36
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for C4orf36
- Search GeneCopoeia for miRNA 3'UTR Target clone products for C4orf36
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for C4orf36
Sources for C4orf36 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB