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Aliases for C4orf17 Gene

Aliases for C4orf17 Gene

  • Chromosome 4 Open Reading Frame 17 2 3 5
  • Uncharacterized Protein C4orf17 3

External Ids for C4orf17 Gene

Previous GeneCards Identifiers for C4orf17 Gene

  • GC04P100790
  • GC04P100651
  • GC04P100432
  • GC04P096170

Summaries for C4orf17 Gene

GeneCards Summary for C4orf17 Gene

C4orf17 (Chromosome 4 Open Reading Frame 17) is a Protein Coding gene.

Additional gene information for C4orf17 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C4orf17 Gene

Genomics for C4orf17 Gene

GeneHancer (GH) Regulatory Elements for C4orf17 Gene

Promoters and enhancers for C4orf17 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH04J099510 Promoter 0.5 EPDnew 650.7 0.0 -2 0.1 C4orf17 ENSG00000250300
GH04J099944 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 11.8 +437.1 437147 6.6 CLOCK MLX FEZF1 DMAP1 IRF4 YY1 ZNF213 E2F8 ZNF143 SP3 DNAJB14 LAMTOR3 LOC256880 H2AFZ LINC01218 LINC01216 PCNAP1 FAM177A1P1 C4orf17 DAPP1
GH04J099535 Enhancer 0.6 ENCODE 11.5 +25.5 25509 1.2 SOX5 SOX13 FOXA2 RXRA RARA NR2F2 POLR2A NR2F6 BCL6 FOXP1 MTTP C4orf17
GH04J099539 Enhancer 0.2 ENCODE 10.8 +29.2 29208 1.8 MTTP TRMT10A C4orf17 ADH1B
GH04J099561 Enhancer 1 Ensembl ENCODE 0.2 +50.3 50297 0.6 HDAC1 PKNOX1 ATF1 RAD21 CHAMP1 GTF3C2 POLR3A FOS RCOR1 CREM MTTP LOC100507053 TRMT10A C4orf17
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around C4orf17 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the C4orf17 gene promoter:

Genomic Locations for C4orf17 Gene

Genomic Locations for C4orf17 Gene
31,300 bases
Plus strand

Genomic View for C4orf17 Gene

Genes around C4orf17 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C4orf17 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C4orf17 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C4orf17 Gene

Proteins for C4orf17 Gene

  • Protein details for C4orf17 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Uncharacterized protein C4orf17
    Protein Accession:
    Secondary Accessions:
    • Q6FI84
    • Q6IS77
    • Q8NA78
    • Q9H0D9

    Protein attributes for C4orf17 Gene

    359 amino acids
    Molecular mass:
    39644 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for C4orf17 Gene


neXtProt entry for C4orf17 Gene

Post-translational modifications for C4orf17 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C4orf17 Gene

No data available for DME Specific Peptides for C4orf17 Gene

Domains & Families for C4orf17 Gene

Gene Families for C4orf17 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for C4orf17 Gene


Suggested Antigen Peptide Sequences for C4orf17 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C4orf17: view

No data available for UniProtKB/Swiss-Prot for C4orf17 Gene

Function for C4orf17 Gene

Phenotypes From GWAS Catalog for C4orf17 Gene

genes like me logo Genes that share phenotypes with C4orf17: view

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C4orf17 Gene

Localization for C4orf17 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for C4orf17 gene
Compartment Confidence
mitochondrion 2
nucleus 2
cytosol 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for C4orf17 Gene

Pathways & Interactions for C4orf17 Gene

SuperPathways for C4orf17 Gene

No Data Available

Interacting Proteins for C4orf17 Gene

Gene Ontology (GO) - Biological Process for C4orf17 Gene


No data available for Pathways by source and SIGNOR curated interactions for C4orf17 Gene

Drugs & Compounds for C4orf17 Gene

No Compound Related Data Available

Transcripts for C4orf17 Gene

mRNA/cDNA for C4orf17 Gene

(22) Selected AceView cDNA sequences:
(7) Additional mRNA sequences :
(2) REFSEQ mRNAs :
(4) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for C4orf17 Gene

Chromosome 4 open reading frame 17:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for C4orf17 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11
SP1: -
SP2: - -
SP4: - -

Relevant External Links for C4orf17 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C4orf17 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for C4orf17 Gene

mRNA differential expression in normal tissues according to GTEx for C4orf17 Gene

This gene is overexpressed in Testis (x51.7).

Protein differential expression in normal tissues from HIPED for C4orf17 Gene

This gene is overexpressed in Liver, secretome (66.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C4orf17 Gene

Protein tissue co-expression partners for C4orf17 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of C4orf17 Gene:


SOURCE GeneReport for Unigene cluster for C4orf17 Gene:

genes like me logo Genes that share expression patterns with C4orf17: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for C4orf17 Gene

Orthologs for C4orf17 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C4orf17 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia C4H4orf17 33
  • 99.26 (n)
C4orf17 34
  • 99 (a)
(Bos Taurus)
Mammalia C6H4orf17 33
  • 84.58 (n)
C4orf17 34
  • 76 (a)
(Canis familiaris)
Mammalia C32H4orf17 33
  • 84.37 (n)
C4orf17 34
  • 75 (a)
(Rattus norvegicus)
Mammalia RGD1309170 33
  • 73.12 (n)
(Mus musculus)
Mammalia 4930579F01Rik 16 34 33
  • 70.85 (n)
(Monodelphis domestica)
Mammalia C4orf17 34
  • 46 (a)
(Anolis carolinensis)
Reptilia C4orf17 34
  • 28 (a)
Species where no ortholog for C4orf17 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C4orf17 Gene

Gene Tree for C4orf17 (if available)
Gene Tree for C4orf17 (if available)

Paralogs for C4orf17 Gene

No data available for Paralogs for C4orf17 Gene

Variants for C4orf17 Gene

Sequence variations from dbSNP and Humsavar for C4orf17 Gene

SNP ID Clin Chr 04 pos Variation AA Info Type
rs10000018 -- 99,537,291(+) A/G intron_variant
rs1000064080 -- 99,525,759(+) T/C intron_variant
rs1000079019 -- 99,519,715(+) G/A intron_variant
rs1000102870 -- 99,516,605(+) G/C intron_variant
rs1000157121 -- 99,535,156(+) G/A intron_variant

Structural Variations from Database of Genomic Variants (DGV) for C4orf17 Gene

Variant ID Type Subtype PubMed ID
dgv51e213 CNV gain 24956385
dgv5345n100 CNV gain 25217958
esv3584519 CNV gain 24956385

Variation tolerance for C4orf17 Gene

Residual Variation Intolerance Score: 75.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 5.60; 72.48% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for C4orf17 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C4orf17 Gene

Disorders for C4orf17 Gene

Additional Disease Information for C4orf17

No disorders were found for C4orf17 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C4orf17 Gene

Publications for C4orf17 Gene

  1. Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PMID: 11230166) Wiemann S … Poustka A (Genome research 2001) 2 3 4 58
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
  4. Phospho-tyrosine dependent protein-protein interaction network. (PMID: 25814554) Grossmann A … Stelzl U (Molecular systems biology 2015) 3 58
  5. Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid. (PMID: 23319000) Luykx JJ … Ophoff RA (Molecular psychiatry 2014) 3 58

Products for C4orf17 Gene

Sources for C4orf17 Gene

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